5C6H

Mcl-1 complexed with Mule

Summary for 5C6H

Entry DOI	10.2210/pdb5c6h/pdb
Descriptor	Induced myeloid leukemia cell differentiation protein Mcl-1, Mule BH3 peptide from E3 ubiquitin-protein ligase HUWE1 (3 entities in total)
Functional Keywords	complex. mcl-1, mule, bh3, apoptosis-apoptosis regulator complex, apoptosis/apoptosis regulator
Biological source	Homo sapiens (Human) More
Cellular location	Membrane ; Single-pass membrane protein : Q07820 Cytoplasm : Q7Z6Z7
Total number of polymer chains	24
Total formula weight	250735.57
Authors	Song, T.,Wang, Z.,Ji, F.,Chai, G.,Liu, Y.,Li, X.,Li, Z.,Fan, Y.,Zhang, Z. (deposition date: 2015-06-23, release date: 2016-08-03, Last modification date: 2024-03-20)
Primary citation	Song, T.,Wang, Z.,Ji, F.,Chai, G.,Liu, Y.,Li, X.,Li, Z.,Fan, Y.,Zhang, Z. Structure of Mcl-1 complexed with Mule at 2.05 Angstroms resolution To Be Published,
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation