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5C6H

Mcl-1 complexed with Mule

Functional Information from GO Data
ChainGOidnamespacecontents
A0042981biological_processregulation of apoptotic process
C0042981biological_processregulation of apoptotic process
E0042981biological_processregulation of apoptotic process
G0042981biological_processregulation of apoptotic process
I0042981biological_processregulation of apoptotic process
K0042981biological_processregulation of apoptotic process
M0042981biological_processregulation of apoptotic process
O0042981biological_processregulation of apoptotic process
Q0042981biological_processregulation of apoptotic process
S0042981biological_processregulation of apoptotic process
U0042981biological_processregulation of apoptotic process
W0042981biological_processregulation of apoptotic process
Functional Information from PROSITE/UniProt
site_idPS01080
Number of Residues20
DetailsBH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. VFsDGvtNWGRIVTLIsFGA
ChainResidueDetails
AVAL253-ALA272

site_idPS01258
Number of Residues12
DetailsBH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WLvkqRGWDgFV
ChainResidueDetails
ATRP305-VAL316

site_idPS01259
Number of Residues15
DetailsBH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. AletLRrVGDGVQRN
ChainResidueDetails
AALA209-ASN223

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues168
DetailsMotif: {"description":"BH3"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues240
DetailsMotif: {"description":"BH1"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues180
DetailsMotif: {"description":"BH2"}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues36
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)"}
ChainResidueDetails

239803

PDB entries from 2025-08-06

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