5KQL

Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid

Summary for 5KQL

Entry DOI	10.2210/pdb5kql/pdb
Related	5KQG 5KQM 5KQP
Descriptor	Low molecular weight phosphotyrosine protein phosphatase, (1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid (3 entities in total)
Functional Keywords	lmw-ptp, inhibitor, complex, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm: P24666
Total number of polymer chains	1
Total formula weight	20528.20
Authors	Wang, J.,Zhang, Z.-Y.,Yu, Z.-H. (deposition date: 2016-07-06, release date: 2016-10-12, Last modification date: 2023-10-04)
Primary citation	He, R.,Wang, J.,Yu, Z.H.,Zhang, R.Y.,Liu, S.,Wu, L.,Zhang, Z.Y. Inhibition of low molecular weight protein tyrosine phosphatase by an induced-fit mechanism. J.Med.Chem., 2016 Cited by PubMed: 27676368 DOI: 10.1021/acs.jmedchem.6b00993 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation