5KQL

Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003993	molecular_function	acid phosphatase activity
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0004726	molecular_function	non-membrane spanning protein tyrosine phosphatase activity
A	0005515	molecular_function	protein binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006470	biological_process	protein dephosphorylation
A	0007268	biological_process	chemical synaptic transmission
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0017124	molecular_function	SH3 domain binding
A	0042383	cellular_component	sarcolemma
A	0045202	cellular_component	synapse
A	0070062	cellular_component	extracellular exosome

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 6VY A 200

Chain	Residue
A	CYS12
A	ASP56
A	ARG97
A	ASP129
A	TYR131
A	LEU13
A	GLY14
A	ASN15
A	ILE16
A	CYS17
A	ARG18
A	TYR49
A	PRO54

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P11064","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"UniProtKB","id":"P11064","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P11064","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"9038134","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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