5KQL

Co-crystal structure of LMW-PTP in complex with 2-oxo-1-phenyl-2-(phenylamino)ethanesulfonic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Low molecular weight phosphotyrosine protein phosphatase	polymer	178	20236.9	1	UniProt (P24666) Pfam (PF01451)	Homo sapiens (Human)	LMW-PTPase,Adipocyte acid phosphatase,Low molecular weight cytosolic acid phosphatase,Red cell acid phosphatase 1
2	B (A)	(1~{S})-2-oxidanylidene-1-phenyl-2-phenylazanyl-ethanesulfonic acid	non-polymer		291.3	1	Chemie (6VY)
3	C (A)	water	water		18.0	268	Chemie (HOH)

Sequence modifications

A: 0 - 157 (UniProt: P24666)

PDB	External Database	Details
Met -20	-	initiating methionine
Gly -19	-	expression tag
Ser -18	-	expression tag
Ser -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
Ser -10	-	expression tag
Ser -9	-	expression tag
Gly -8	-	expression tag
Leu -7	-	expression tag
Val -6	-	expression tag
Pro -5	-	expression tag
Arg -4	-	expression tag
Gly -3	-	expression tag
Ser -2	-	expression tag
His -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	20236.9
Non-Polymers*	Number of molecules	1
	Total formula weight	291.3
All*	Total formula weight	20528.2

*Water molecules are not included.