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PDB: 272 件
8FNF
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BU of 8fnf by Molmil
Cryo-EM structure of RNase-untreated RESC-C in trypanosomal RNA editing
分子名称: Mitochondrial RNA binding complex 1 subunit, Mitochondrial RNA binding protein, Phytanoyl-CoA dioxygenase family protein, ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FNI
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BU of 8fni by Molmil
Cryo-EM structure of RNase-treated RESC-B in trypanosomal RNA editing
分子名称: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
8FNK
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BU of 8fnk by Molmil
Cryo-EM structure of RNase-untreated RESC-B in trypanosomal RNA editing
分子名称: RNA-editing substrate-binding complex protein 10 (RESC10), RNA-editing substrate-binding complex protein 11 (RESC11), RNA-editing substrate-binding complex protein 13 (RESC13), ...
著者Liu, S, Wang, H, Li, X, Zhang, F, Lee, J.K.J, Li, Z, Yu, C, Zhao, X, Hu, J.J, Suematsu, T, Alvarez-Cabrera, A.L, Liu, Q, Zhang, L, Huang, L, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
登録日2022-12-27
公開日2023-07-19
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of gRNA stabilization and mRNA recognition in trypanosomal RNA editing.
Science, 381, 2023
3H4P
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BU of 3h4p by Molmil
Proteasome 20S core particle from Methanocaldococcus jannaschii
分子名称: Proteasome subunit alpha, Proteasome subunit beta
著者Jeffrey, P.D, Zhang, F, Hu, M, Tian, G, Zhang, P, Finley, D, Shi, Y.
登録日2009-04-20
公開日2009-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4.1 Å)
主引用文献Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschii.
Mol.Cell, 34, 2009
7VT1
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BU of 7vt1 by Molmil
Acyltransferase from the 9th Module of Salinomycin Polyketide Synthase
分子名称: Type I modular polyketide synthase
著者Feng, Y, Zhang, F, Zheng, J.
登録日2021-10-27
公開日2022-06-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural visualization of transient interactions between the cis-acting acyltransferase and acyl carrier protein of the salinomycin modular polyketide synthase.
Acta Crystallogr D Struct Biol, 78, 2022
3E64
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BU of 3e64 by Molmil
Fragment based discovery of JAK-2 inhibitors
分子名称: 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide, Tyrosine-protein kinase JAK2
著者Antonysamy, S, Fang, W, Hirst, G, Park, F, Russell, M, Smyth, L, Sprengeler, P, Stappenbeck, F, Steensma, R, Thompson, D.A, Wilson, M, Wong, M, Zhang, A, Zhang, F.
登録日2008-08-14
公開日2008-10-14
最終更新日2012-02-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Fragment-based discovery of JAK-2 inhibitors.
Bioorg.Med.Chem.Lett., 19, 2009
2P1G
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BU of 2p1g by Molmil
Crystal structure of a putative xylanase from Bacteroides fragilis
分子名称: Putative xylanase
著者Bonanno, J.B, Freeman, J, Bain, K.T, Zhang, F, Sridhar, V, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-05
公開日2007-03-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a putative xylanase from Bacteroides fragilis
To be Published
1MR1
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BU of 1mr1 by Molmil
Crystal Structure of a Smad4-Ski Complex
分子名称: Mothers against decapentaplegic homolog 4, Ski oncogene, ZINC ION
著者Wu, J.-W, Krawitz, A.R, Chai, J, Li, W, Zhang, F, Luo, K, Shi, Y.
登録日2002-09-17
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski: Insights on Ski-mediated Repression of TGF-beta Signaling
Cell(Cambridge,Mass.), 111, 2002
8GKH
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BU of 8gkh by Molmil
Structure of the Spizellomyces punctatus Fanzor (SpuFz) in complex with omega RNA and target DNA
分子名称: DNA (35-MER), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ...
著者Xu, P, Saito, M, Zhang, F.
登録日2023-03-19
公開日2023-07-05
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Fanzor is a eukaryotic programmable RNA-guided endonuclease.
Nature, 620, 2023
8GH6
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BU of 8gh6 by Molmil
Bombyx mori R2 retrotransposon initiating target-primed reverse transcription
分子名称: 28S DNA bottom strand, 3' side, 5' side (priming strand), ...
著者Wilkinson, M.E, Zhang, F.
登録日2023-03-09
公開日2023-04-05
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.08 Å)
主引用文献Structure of the R2 non-LTR retrotransposon initiating target-primed reverse transcription.
Science, 380, 2023
2P2U
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BU of 2p2u by Molmil
Crystal structure of putative host-nuclease inhibitor protein Gam from Desulfovibrio vulgaris
分子名称: Host-nuclease inhibitor protein Gam, putative
著者Bonanno, J.B, Rutter, M, Bain, K.T, Zhang, F, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-03-07
公開日2007-03-27
最終更新日2021-02-03
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of putative host-nuclease inhibitor protein Gam from Desulfovibrio vulgaris
To be Published
8FC7
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BU of 8fc7 by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with GSK2798745
分子名称: 1-({(5S,7S)-3-[5-(2-hydroxypropan-2-yl)pyrazin-2-yl]-7-methyl-2-oxo-1-oxa-3-azaspiro[4.5]decan-7-yl}methyl)-1H-benzimidazole-6-carbonitrile, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
8FC9
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BU of 8fc9 by Molmil
Cryo-EM structure of the human TRPV4 - RhoA, apo condition
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Transforming protein RhoA, ...
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.75 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
4G1R
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BU of 4g1r by Molmil
Crystal structure of anti-HIV actinohivin in complex with alphs-1,2-mannobiose (Form II)
分子名称: Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A.
登録日2012-07-11
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Matured structure of anti-HIV lectin actinohivin in complex with alpha-1,2-mannobiose
To be Published
8FC8
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BU of 8fc8 by Molmil
Cryo-EM structure of the human TRPV4 in complex with GSK1016790A
分子名称: CHOLESTEROL HEMISUCCINATE, N-[(2S)-1-{4-[N-(2,4-dichlorobenzene-1-sulfonyl)-L-seryl]piperazin-1-yl}-4-methyl-1-oxopentan-2-yl]-1-benzothiophene-2-carboxamide, Transient receptor potential cation channel subfamily V member 4
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
4DEN
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BU of 4den by Molmil
Structural insightsinto potent, specific anti-HIV property of actinohivin; Crystal structure of actinohivin in complex with alpha(1-2) mannobiose moiety of high-mannose type glycan of gp120
分子名称: Actinohivin, POTASSIUM ION, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A.
登録日2012-01-20
公開日2012-11-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the alpha(1–2)mannobiose moiety of gp120
Acta Crystallogr.,Sect.D, 68, 2012
8FCA
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BU of 8fca by Molmil
Cryo-EM structure of the human TRPV4 - RhoA in complex with 4alpha-Phorbol 12,13-didecanoate
分子名称: (1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-9a-(decanoyloxy)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1a,1b,4,4a,5,7a,7b,8,9,9a-decahydro-1H-cyclopropa[3,4]benzo[1,2-e]azulen-9-yl decanoate, CHOLESTEROL HEMISUCCINATE, Transient receptor potential cation channel subfamily V member 4
著者Kwon, D.H, Lee, S.-Y, Zhang, F.
登録日2022-12-01
公開日2023-07-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献TRPV4-Rho GTPase complex structures reveal mechanisms of gating and disease.
Nat Commun, 14, 2023
5T0Q
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BU of 5t0q by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 Jas domain [166-192] from arabidopsis
分子名称: Protein TIFY 9, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
登録日2016-08-16
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5T0F
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BU of 5t0f by Molmil
Crystal structure of the Myc3 N-terminal domain [44-242] in complex with JAZ10 CMID domain [16-58] from arabidopsis
分子名称: Protein TIFY 9, Transcription factor MYC3
著者Ke, J, Zhang, F, Brunzelle, J.S, He, S.Y, Xu, H.E, Melcher, K.
登録日2016-08-16
公開日2017-01-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural insights into alternative splicing-mediated desensitization of jasmonate signaling.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4END
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BU of 4end by Molmil
Crystal structure of anti-HIV actinohivin in complex with alpha-1,2-mannobiose (P 2 21 21 form)
分子名称: ACETONITRILE, Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose
著者Hoque, M.M, Suzuki, K, Tsunoda, M, Jiang, J, Zhang, F, Takahashi, A, Naomi, O, Zhang, X, Sekiguchi, T, Tanaka, H, Omura, S, Takenaka, A.
登録日2012-04-13
公開日2013-07-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Matured structure of anti-HIV lectin actinohivin in complex with 1,2-mannobiose
To be Published
3ISS
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BU of 3iss by Molmil
Crystal structure of enolpyruvyl-UDP-GlcNAc synthase (MurA):UDP-N-acetylmuramic acid:phosphite from Escherichia coli
分子名称: PHOSPHITE ION, UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID
著者Jackson, S.G, Zhang, F, Chindemi, P, Junop, M.S, Berti, P.J.
登録日2009-08-27
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions .
Biochemistry, 48, 2009
6RPJ
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BU of 6rpj by Molmil
A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, A non-blocking CTLA-4 nanobody, Cytotoxic T-lymphocyte protein 4, ...
著者Gao, H, Zhou, A, Zhang, F.
登録日2019-05-14
公開日2020-07-08
最終更新日2020-11-11
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献A Non-blocking anti-CTLA-4 Nanobody complexed with CTLA-4
To Be Published
5GYL
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BU of 5gyl by Molmil
Structure of Cicer arietinum 11S gloubulin
分子名称: legumin-like protein
著者Zhou, A, Zhang, F.
登録日2016-09-22
公開日2017-10-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallization and crystallographic studies of a novel chickpea 11S globulin.
Acta Crystallogr.,Sect.F, 78, 2022
4YM6
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BU of 4ym6 by Molmil
Crystal structure of the human nucleosome containing 6-4PP (outside)
分子名称: 145-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Osakabe, A, Tachiwana, H, Kagawa, W, Horikoshi, N, Matsumoto, S, Hasegawa, M, Matsumoto, N, Toga, T, Yamamoto, J, Hanaoka, F, Thoma, N.H, Sugasawa, K, Iwai, S, Kurumizaka, H.
登録日2015-03-06
公開日2015-12-02
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.514 Å)
主引用文献Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome
Sci Rep, 5, 2015
5XXY
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BU of 5xxy by Molmil
Crystal structure of PD-L1 complexed with atezolizumab fab at 2.9A
分子名称: Programmed cell death 1 ligand 1, heavy chain of atezolizumab fab, light chain of atezolizumab fab
著者Zhou, A, Zhang, F.
登録日2017-07-05
公開日2017-09-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of the therapeutic anti-PD-L1 antibody atezolizumab.
Oncotarget, 8, 2017

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