3ISS

Crystal structure of enolpyruvyl-UDP-GlcNAc synthase (MurA):UDP-N-acetylmuramic acid:phosphite from Escherichia coli

Summary for 3ISS

• Entry DOI: 10.2210/pdb3iss/pdb
• Related: 1A2N 1DLG 1EYN 1Q3G 1UAE 2Z2C
• Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, PHOSPHITE ION, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL) BUTYRIC ACID, ... (4 entities in total)
• Functional Keywords: protein-ligand, cell cycle, cell division, cell shape, cell wall biogenesis/degradation, peptidoglycan synthesis, transferase
• Biological source: Escherichia coli K-12
• Cellular location: Cytoplasm (Probable): P0A749
• Total number of polymer chains: 12
• Total formula weight: 545997.34

Authors

Jackson, S.G.,Zhang, F.,Chindemi, P.,Junop, M.S.,Berti, P.J. (deposition date: 2009-08-27, release date: 2009-11-24, Last modification date: 2023-09-06)

• Primary citation: Jackson, S.G.,Zhang, F.,Chindemi, P.,Junop, M.S.,Berti, P.J.; Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions .; Biochemistry, 48:11715-11723, 2009; PubMed: 19899805; DOI: 10.1021/bi901524q

Experimental method

X-RAY DIFFRACTION (2.5 Å)