1Q3G

MurA (Asp305Ala) liganded with tetrahedral reaction intermediate

Summary for 1Q3G

Entry DOI	10.2210/pdb1q3g/pdb
Related	1a2n 1ejc 1ejd 1eyn 1naw 1q36 1uae
Descriptor	UDP-N-acetylglucosamine 1-carboxyvinyltransferase, 3'-1-CARBOXY-1-PHOSPHONOOXY-ETHOXY-URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	inside-out alpha-beta barrel, transferase
Biological source	Enterobacter cloacae
Cellular location	Cytoplasm : P33038
Total number of polymer chains	16
Total formula weight	729965.79
Authors	Eschenburg, S.,Kabsch, W.,Healy, M.L.,Schonbrunn, E. (deposition date: 2003-07-29, release date: 2003-12-16, Last modification date: 2023-08-16)
Primary citation	Eschenburg, S.,Kabsch, W.,Healy, M.L.,Schonbrunn, E. A New View of the Mechanisms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA) and 5-Enolpyruvylshikimate-3-phosphate Synthase (AroA) Derived from X-ray Structures of Their Tetrahedral Reaction Intermediate States. J.Biol.Chem., 278:49215-49222, 2003 Cited by PubMed: 13129913 DOI: 10.1074/jbc.M309741200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.65 Å)

Structure validation