Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1Q3G

MurA (Asp305Ala) liganded with tetrahedral reaction intermediate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005737	cellular_component	cytoplasm
A	0008360	biological_process	regulation of cell shape
A	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
A	0051301	biological_process	cell division
A	0071555	biological_process	cell wall organization
B	0003824	molecular_function	catalytic activity
B	0005737	cellular_component	cytoplasm
B	0008360	biological_process	regulation of cell shape
B	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
B	0009252	biological_process	peptidoglycan biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
B	0051301	biological_process	cell division
B	0071555	biological_process	cell wall organization
C	0003824	molecular_function	catalytic activity
C	0005737	cellular_component	cytoplasm
C	0008360	biological_process	regulation of cell shape
C	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
C	0009252	biological_process	peptidoglycan biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
C	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
C	0051301	biological_process	cell division
C	0071555	biological_process	cell wall organization
D	0003824	molecular_function	catalytic activity
D	0005737	cellular_component	cytoplasm
D	0008360	biological_process	regulation of cell shape
D	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
D	0009252	biological_process	peptidoglycan biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
D	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
D	0051301	biological_process	cell division
D	0071555	biological_process	cell wall organization
E	0003824	molecular_function	catalytic activity
E	0005737	cellular_component	cytoplasm
E	0008360	biological_process	regulation of cell shape
E	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
E	0009252	biological_process	peptidoglycan biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
E	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
E	0051301	biological_process	cell division
E	0071555	biological_process	cell wall organization
F	0003824	molecular_function	catalytic activity
F	0005737	cellular_component	cytoplasm
F	0008360	biological_process	regulation of cell shape
F	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
F	0009252	biological_process	peptidoglycan biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
F	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
F	0051301	biological_process	cell division
F	0071555	biological_process	cell wall organization
G	0003824	molecular_function	catalytic activity
G	0005737	cellular_component	cytoplasm
G	0008360	biological_process	regulation of cell shape
G	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
G	0009252	biological_process	peptidoglycan biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
G	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
G	0051301	biological_process	cell division
G	0071555	biological_process	cell wall organization
H	0003824	molecular_function	catalytic activity
H	0005737	cellular_component	cytoplasm
H	0008360	biological_process	regulation of cell shape
H	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
H	0009252	biological_process	peptidoglycan biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
H	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
H	0051301	biological_process	cell division
H	0071555	biological_process	cell wall organization
I	0003824	molecular_function	catalytic activity
I	0005737	cellular_component	cytoplasm
I	0008360	biological_process	regulation of cell shape
I	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
I	0009252	biological_process	peptidoglycan biosynthetic process
I	0016740	molecular_function	transferase activity
I	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
I	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
I	0051301	biological_process	cell division
I	0071555	biological_process	cell wall organization
J	0003824	molecular_function	catalytic activity
J	0005737	cellular_component	cytoplasm
J	0008360	biological_process	regulation of cell shape
J	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
J	0009252	biological_process	peptidoglycan biosynthetic process
J	0016740	molecular_function	transferase activity
J	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
J	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
J	0051301	biological_process	cell division
J	0071555	biological_process	cell wall organization
K	0003824	molecular_function	catalytic activity
K	0005737	cellular_component	cytoplasm
K	0008360	biological_process	regulation of cell shape
K	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
K	0009252	biological_process	peptidoglycan biosynthetic process
K	0016740	molecular_function	transferase activity
K	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
K	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
K	0051301	biological_process	cell division
K	0071555	biological_process	cell wall organization
L	0003824	molecular_function	catalytic activity
L	0005737	cellular_component	cytoplasm
L	0008360	biological_process	regulation of cell shape
L	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
L	0009252	biological_process	peptidoglycan biosynthetic process
L	0016740	molecular_function	transferase activity
L	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
L	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
L	0051301	biological_process	cell division
L	0071555	biological_process	cell wall organization
W	0003824	molecular_function	catalytic activity
W	0005737	cellular_component	cytoplasm
W	0008360	biological_process	regulation of cell shape
W	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
W	0009252	biological_process	peptidoglycan biosynthetic process
W	0016740	molecular_function	transferase activity
W	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
W	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
W	0051301	biological_process	cell division
W	0071555	biological_process	cell wall organization
X	0003824	molecular_function	catalytic activity
X	0005737	cellular_component	cytoplasm
X	0008360	biological_process	regulation of cell shape
X	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
X	0009252	biological_process	peptidoglycan biosynthetic process
X	0016740	molecular_function	transferase activity
X	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
X	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
X	0051301	biological_process	cell division
X	0071555	biological_process	cell wall organization
Y	0003824	molecular_function	catalytic activity
Y	0005737	cellular_component	cytoplasm
Y	0008360	biological_process	regulation of cell shape
Y	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
Y	0009252	biological_process	peptidoglycan biosynthetic process
Y	0016740	molecular_function	transferase activity
Y	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
Y	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
Y	0051301	biological_process	cell division
Y	0071555	biological_process	cell wall organization
Z	0003824	molecular_function	catalytic activity
Z	0005737	cellular_component	cytoplasm
Z	0008360	biological_process	regulation of cell shape
Z	0008760	molecular_function	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
Z	0009252	biological_process	peptidoglycan biosynthetic process
Z	0016740	molecular_function	transferase activity
Z	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
Z	0019277	biological_process	UDP-N-acetylgalactosamine biosynthetic process
Z	0051301	biological_process	cell division
Z	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	BINDING SITE FOR RESIDUE UDA A 1450

Chain	Residue
A	LYS22
A	LYS160
A	SER162
A	VAL163
A	GLY164
A	THR304
A	ALA305
A	ILE327
A	PHE328
A	ARG331
A	LEU370
A	ASN23
A	ARG371
A	ARG397
A	HOH427
A	HOH431
A	HOH435
A	HOH442
A	HOH443
A	HOH795
A	HOH1096
A	EDO1470
A	TRP95
A	ARG120
A	PRO121
A	VAL122
A	ASP123
A	LEU124
A	HIS125

site_id	AC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE UDA B 1451

Chain	Residue
B	LYS22
B	ASN23
B	TRP95
B	ARG120
B	PRO121
B	VAL122
B	ASP123
B	LEU124
B	HIS125
B	LYS160
B	SER162
B	VAL163
B	GLY164
B	GLU188
B	THR304
B	ALA305
B	ILE327
B	PHE328
B	ARG331
B	LEU370
B	ARG371
B	HOH422
B	HOH430
B	HOH442
B	HOH561
B	HOH1202
B	EDO1471

site_id	AC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE UDA C 1452

Chain	Residue
C	LYS22
C	ASN23
C	TRP95
C	ARG120
C	PRO121
C	VAL122
C	ASP123
C	LEU124
C	HIS125
C	LYS160
C	SER162
C	VAL163
C	GLY164
C	THR304
C	ALA305
C	ILE327
C	PHE328
C	ARG331
C	LEU370
C	ARG371
C	ARG397
C	HOH434
C	HOH590
C	HOH789
C	HOH853
C	HOH1098
C	HOH1147
C	EDO1472

site_id	AC4
Number of Residues	29
Details	BINDING SITE FOR RESIDUE UDA D 1453

Chain	Residue
D	ILE327
D	PHE328
D	ARG331
D	LEU370
D	ARG371
D	ARG397
D	HOH423
D	HOH434
D	HOH452
D	HOH456
D	HOH640
D	HOH734
D	HOH969
D	EDO1473
D	LYS22
D	ASN23
D	TRP95
D	ARG120
D	PRO121
D	VAL122
D	ASP123
D	LEU124
D	HIS125
D	LYS160
D	SER162
D	VAL163
D	GLY164
D	THR304
D	ALA305

site_id	AC5
Number of Residues	29
Details	BINDING SITE FOR RESIDUE UDA E 1454

Chain	Residue
E	LYS22
E	ASN23
E	TRP95
E	ARG120
E	PRO121
E	VAL122
E	ASP123
E	LEU124
E	HIS125
E	LYS160
E	SER162
E	VAL163
E	GLY164
E	THR304
E	ALA305
E	ILE327
E	PHE328
E	ARG331
E	LEU370
E	ARG371
E	ARG397
E	HOH421
E	HOH439
E	HOH443
E	HOH444
E	HOH448
E	HOH549
E	HOH1046
E	EDO1474

site_id	AC6
Number of Residues	27
Details	BINDING SITE FOR RESIDUE UDA F 1455

Chain	Residue
F	LYS22
F	ASN23
F	TRP95
F	ARG120
F	PRO121
F	VAL122
F	ASP123
F	LEU124
F	HIS125
F	LYS160
F	SER162
F	VAL163
F	GLY164
F	GLU188
F	THR304
F	ALA305
F	ILE327
F	PHE328
F	ARG331
F	LEU370
F	ARG371
F	HOH450
F	HOH541
F	HOH575
F	HOH677
F	HOH722
F	EDO1475

site_id	AC7
Number of Residues	32
Details	BINDING SITE FOR RESIDUE UDA G 1456

Chain	Residue
G	LYS22
G	ASN23
G	TRP95
G	ARG120
G	PRO121
G	VAL122
G	ASP123
G	LEU124
G	HIS125
G	LYS160
G	SER162
G	VAL163
G	GLY164
G	GLU188
G	THR304
G	ALA305
G	ILE327
G	PHE328
G	ARG331
G	LEU370
G	ARG371
G	ARG397
G	HOH422
G	HOH424
G	HOH462
G	HOH468
G	HOH683
G	HOH744
G	HOH956
G	HOH1169
G	HOH1242
G	EDO1476

site_id	AC8
Number of Residues	28
Details	BINDING SITE FOR RESIDUE UDA H 1457

Chain	Residue
H	LYS22
H	ASN23
H	TRP95
H	ARG120
H	PRO121
H	VAL122
H	ASP123
H	LEU124
H	HIS125
H	SER162
H	VAL163
H	GLY164
H	THR304
H	ALA305
H	ILE327
H	PHE328
H	ARG331
H	LEU370
H	ARG371
H	ARG397
H	HOH420
H	HOH427
H	HOH430
H	HOH435
H	HOH612
H	HOH778
H	HOH935
H	EDO1477

site_id	AC9
Number of Residues	27
Details	BINDING SITE FOR RESIDUE UDA I 1458

Chain	Residue
I	LYS22
I	ASN23
I	TRP95
I	ARG120
I	PRO121
I	VAL122
I	ASP123
I	LEU124
I	HIS125
I	LYS160
I	SER162
I	VAL163
I	GLY164
I	THR304
I	ALA305
I	ILE327
I	PHE328
I	ARG331
I	LEU370
I	ARG371
I	ARG397
I	HOH420
I	HOH424
I	HOH434
I	HOH441
I	HOH518
I	EDO1478

site_id	BC1
Number of Residues	26
Details	BINDING SITE FOR RESIDUE UDA J 1459

Chain	Residue
J	LYS22
J	ASN23
J	TRP95
J	ARG120
J	PRO121
J	VAL122
J	ASP123
J	LEU124
J	HIS125
J	LYS160
J	SER162
J	VAL163
J	GLY164
J	THR304
J	ALA305
J	ILE327
J	PHE328
J	ARG331
J	LEU370
J	ARG371
J	ARG397
J	HOH422
J	HOH426
J	HOH616
J	HOH840
J	EDO1479

site_id	BC2
Number of Residues	29
Details	BINDING SITE FOR RESIDUE UDA K 1460

Chain	Residue
K	LYS22
K	ASN23
K	TRP95
K	ARG120
K	PRO121
K	VAL122
K	ASP123
K	LEU124
K	HIS125
K	LYS160
K	SER162
K	VAL163
K	GLY164
K	THR304
K	ALA305
K	ILE327
K	PHE328
K	ARG331
K	LEU370
K	ARG371
K	HOH424
K	HOH428
K	HOH429
K	HOH435
K	HOH437
K	HOH439
K	HOH740
K	HOH1309
K	EDO1480

site_id	BC3
Number of Residues	28
Details	BINDING SITE FOR RESIDUE UDA L 1461

Chain	Residue
L	LYS22
L	ASN23
L	TRP95
L	ARG120
L	PRO121
L	VAL122
L	ASP123
L	LEU124
L	HIS125
L	LYS160
L	SER162
L	VAL163
L	GLY164
L	GLU188
L	THR304
L	ALA305
L	ILE327
L	PHE328
L	ARG331
L	LEU370
L	ARG371
L	ARG397
L	HOH583
L	HOH831
L	HOH851
L	HOH1023
L	HOH1276
L	EDO1481

site_id	BC4
Number of Residues	30
Details	BINDING SITE FOR RESIDUE UDA W 1462

Chain	Residue
W	LYS22
W	ASN23
W	TRP95
W	ARG120
W	PRO121
W	VAL122
W	ASP123
W	LEU124
W	HIS125
W	LYS160
W	SER162
W	VAL163
W	GLY164
W	THR304
W	ALA305
W	ILE327
W	PHE328
W	ARG331
W	LEU370
W	ARG371
W	ARG397
W	HOH420
W	HOH434
W	HOH439
W	HOH704
W	HOH731
W	HOH1061
W	HOH1137
W	HOH1214
W	EDO1482

site_id	BC5
Number of Residues	23
Details	BINDING SITE FOR RESIDUE UDA X 1463

Chain	Residue
X	LYS22
X	ASN23
X	TRP95
X	ARG120
X	PRO121
X	VAL122
X	ASP123
X	LEU124
X	HIS125
X	LYS160
X	SER162
X	VAL163
X	GLY164
X	THR304
X	ALA305
X	ILE327
X	ARG331
X	LEU370
X	ARG371
X	ARG397
X	HOH550
X	HOH1048
X	EDO1483

site_id	BC6
Number of Residues	25
Details	BINDING SITE FOR RESIDUE UDA Y 1464

Chain	Residue
Y	LYS22
Y	ASN23
Y	TRP95
Y	ARG120
Y	PRO121
Y	VAL122
Y	ASP123
Y	LEU124
Y	HIS125
Y	SER162
Y	VAL163
Y	GLY164
Y	THR304
Y	ALA305
Y	ILE327
Y	PHE328
Y	ARG331
Y	LEU370
Y	ARG371
Y	HOH433
Y	HOH435
Y	HOH686
Y	HOH1178
Y	HOH1387
Y	EDO1484

site_id	BC7
Number of Residues	26
Details	BINDING SITE FOR RESIDUE UDA Z 1465

Chain	Residue
Z	LYS22
Z	ASN23
Z	TRP95
Z	ARG120
Z	PRO121
Z	VAL122
Z	ASP123
Z	LEU124
Z	HIS125
Z	LYS160
Z	SER162
Z	VAL163
Z	GLY164
Z	THR304
Z	ALA305
Z	ILE327
Z	PHE328
Z	ARG331
Z	LEU370
Z	ARG371
Z	HOH424
Z	HOH429
Z	HOH432
Z	HOH643
Z	HOH775
Z	EDO1485

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1470

Chain	Residue
A	ARG120
A	HIS125
A	GLY164
A	UDA1450

site_id	BC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO B 1471

Chain	Residue
B	ARG91
B	GLY164
B	HOH430
B	UDA1451

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO C 1472

Chain	Residue
C	ARG91
C	ARG120
C	GLY164
C	HOH590
C	UDA1452

site_id	CC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO D 1473

Chain	Residue
D	HIS125
D	GLY164
D	HOH433
D	HOH1319
D	UDA1453

site_id	CC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO E 1474

Chain	Residue
E	ALA92
E	ILE94
E	TRP95
E	ARG120
E	GLY164
E	HOH448
E	UDA1454

site_id	CC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO F 1475

Chain	Residue
F	HIS125
F	GLY164
F	UDA1455

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO G 1476

Chain	Residue
G	ARG91
G	ARG120
G	GLY164
G	HOH422
G	UDA1456

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO H 1477

Chain	Residue
H	GLY164
H	HOH427
H	UDA1457

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO I 1478

Chain	Residue
I	ARG91
I	ARG120
I	GLY164
I	UDA1458

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO J 1479

Chain	Residue
J	GLY164
J	HOH426
J	UDA1459

site_id	CC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO K 1480

Chain	Residue
K	ARG91
K	TRP95
K	ARG120
K	GLY164
K	HOH429
K	UDA1460

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO L 1481

Chain	Residue
L	ARG91
L	GLY164
L	UDA1461

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO W 1482

Chain	Residue
W	ARG91
W	TRP95
W	ARG120
W	GLY164
W	UDA1462

site_id	DC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO X 1483

Chain	Residue
X	TRP95
X	ARG120
X	GLY164
X	HOH550
X	HOH885
X	UDA1463

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO Y 1484

Chain	Residue
Y	ARG91
Y	GLY164
Y	UDA1464

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO Z 1485

Chain	Residue
Z	ARG91
Z	ARG120
Z	GLY164
Z	UDA1465

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	ACT_SITE: Proton donor => ECO:0000269\|PubMed:20392080, ECO:0000269\|PubMed:22378791, ECO:0007744\|PDB:3LTH

Chain	Residue	Details
A	CYS115
J	CYS115
K	CYS115
L	CYS115
W	CYS115
X	CYS115
Y	CYS115
Z	CYS115
B	CYS115
C	CYS115
D	CYS115
E	CYS115
F	CYS115
G	CYS115
H	CYS115
I	CYS115

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000305\|PubMed:22378791, ECO:0007744\|PDB:3SWQ

Chain	Residue	Details
A	LYS22
J	LYS22
K	LYS22
L	LYS22
W	LYS22
X	LYS22
Y	LYS22
Z	LYS22
B	LYS22
C	LYS22
D	LYS22
E	LYS22
F	LYS22
G	LYS22
H	LYS22
I	LYS22

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00111

Chain	Residue	Details
A	ARG91
J	ARG91
K	ARG91
L	ARG91
W	ARG91
X	ARG91
Y	ARG91
Z	ARG91
B	ARG91
C	ARG91
D	ARG91
E	ARG91
F	ARG91
G	ARG91
H	ARG91
I	ARG91

site_id	SWS_FT_FI4
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269\|PubMed:20392080, ECO:0000269\|PubMed:22378791, ECO:0007744\|PDB:3LTH, ECO:0007744\|PDB:3SWQ

Chain	Residue	Details
A	ARG120
D	ARG120
D	ALA305
D	ILE327
E	ARG120
E	ALA305
E	ILE327
F	ARG120
F	ALA305
F	ILE327
G	ARG120
A	ALA305
G	ALA305
G	ILE327
H	ARG120
H	ALA305
H	ILE327
I	ARG120
I	ALA305
I	ILE327
J	ARG120
J	ALA305
A	ILE327
J	ILE327
K	ARG120
K	ALA305
K	ILE327
L	ARG120
L	ALA305
L	ILE327
W	ARG120
W	ALA305
W	ILE327
B	ARG120
X	ARG120
X	ALA305
X	ILE327
Y	ARG120
Y	ALA305
Y	ILE327
Z	ARG120
Z	ALA305
Z	ILE327
B	ALA305
B	ILE327
C	ARG120
C	ALA305
C	ILE327

site_id	SWS_FT_FI5
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269\|PubMed:22378791, ECO:0007744\|PDB:3SWQ

Chain	Residue	Details
A	LYS160
J	LYS160
K	LYS160
L	LYS160
W	LYS160
X	LYS160
Y	LYS160
Z	LYS160
B	LYS160
C	LYS160
D	LYS160
E	LYS160
F	LYS160
G	LYS160
H	LYS160
I	LYS160

site_id	SWS_FT_FI6
Number of Residues	16
Details	MOD_RES: 2-(S-cysteinyl)pyruvic acid O-phosphothioketal => ECO:0000269\|PubMed:22378791

Chain	Residue	Details
A	CYS115
J	CYS115
K	CYS115
L	CYS115
W	CYS115
X	CYS115
Y	CYS115
Z	CYS115
B	CYS115
C	CYS115
D	CYS115
E	CYS115
F	CYS115
G	CYS115
H	CYS115
I	CYS115

Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
A	ALA305
A	ARG397
A	CYS115
A	ASN23

site_id	CSA10
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
J	ALA305
J	ARG397
J	CYS115
J	ASN23

site_id	CSA11
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
K	ALA305
K	ARG397
K	CYS115
K	ASN23

site_id	CSA12
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
L	ALA305
L	ARG397
L	CYS115
L	ASN23

site_id	CSA13
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
W	ALA305
W	ARG397
W	CYS115
W	ASN23

site_id	CSA14
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
X	ALA305
X	ARG397
X	CYS115
X	ASN23

site_id	CSA15
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
Y	ALA305
Y	ARG397
Y	CYS115
Y	ASN23

site_id	CSA16
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
Z	ALA305
Z	ARG397
Z	CYS115
Z	ASN23

site_id	CSA2
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
B	ALA305
B	ARG397
B	CYS115
B	ASN23

site_id	CSA3
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
C	ALA305
C	ARG397
C	CYS115
C	ASN23

site_id	CSA4
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
D	ALA305
D	ARG397
D	CYS115
D	ASN23

site_id	CSA5
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
E	ALA305
E	ARG397
E	CYS115
E	ASN23

site_id	CSA6
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
F	ALA305
F	ARG397
F	CYS115
F	ASN23

site_id	CSA7
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
G	ALA305
G	ARG397
G	CYS115
G	ASN23

site_id	CSA8
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
H	ALA305
H	ARG397
H	CYS115
H	ASN23

site_id	CSA9
Number of Residues	4
Details	Annotated By Reference To The Literature 1uae

Chain	Residue	Details
I	ALA305
I	ARG397
I	CYS115
I	ASN23

site_id	MCSA1
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
A	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
A	ASN23	electrostatic stabiliser, hydrogen bond donor
A	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
A	ARG120	electrostatic stabiliser, proton acceptor, proton donor
A	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA10
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
J	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
J	ASN23	electrostatic stabiliser, hydrogen bond donor
J	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
J	ARG120	electrostatic stabiliser, proton acceptor, proton donor
J	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
J	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA11
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
K	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
K	ASN23	electrostatic stabiliser, hydrogen bond donor
K	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
K	ARG120	electrostatic stabiliser, proton acceptor, proton donor
K	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
K	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA12
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
L	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
L	ASN23	electrostatic stabiliser, hydrogen bond donor
L	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
L	ARG120	electrostatic stabiliser, proton acceptor, proton donor
L	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
L	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA13
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
W	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
W	ASN23	electrostatic stabiliser, hydrogen bond donor
W	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
W	ARG120	electrostatic stabiliser, proton acceptor, proton donor
W	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
W	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA14
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
X	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
X	ASN23	electrostatic stabiliser, hydrogen bond donor
X	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
X	ARG120	electrostatic stabiliser, proton acceptor, proton donor
X	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
X	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA15
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
Y	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
Y	ASN23	electrostatic stabiliser, hydrogen bond donor
Y	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
Y	ARG120	electrostatic stabiliser, proton acceptor, proton donor
Y	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
Y	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA16
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
Z	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
Z	ASN23	electrostatic stabiliser, hydrogen bond donor
Z	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
Z	ARG120	electrostatic stabiliser, proton acceptor, proton donor
Z	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
Z	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA2
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
B	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
B	ASN23	electrostatic stabiliser, hydrogen bond donor
B	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
B	ARG120	electrostatic stabiliser, proton acceptor, proton donor
B	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA3
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
C	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
C	ASN23	electrostatic stabiliser, hydrogen bond donor
C	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
C	ARG120	electrostatic stabiliser, proton acceptor, proton donor
C	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
C	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA4
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
D	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
D	ASN23	electrostatic stabiliser, hydrogen bond donor
D	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
D	ARG120	electrostatic stabiliser, proton acceptor, proton donor
D	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
D	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA5
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
E	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
E	ASN23	electrostatic stabiliser, hydrogen bond donor
E	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
E	ARG120	electrostatic stabiliser, proton acceptor, proton donor
E	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
E	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA6
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
F	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
F	ASN23	electrostatic stabiliser, hydrogen bond donor
F	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
F	ARG120	electrostatic stabiliser, proton acceptor, proton donor
F	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
F	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA7
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
G	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
G	ASN23	electrostatic stabiliser, hydrogen bond donor
G	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
G	ARG120	electrostatic stabiliser, proton acceptor, proton donor
G	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
G	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA8
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
H	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
H	ASN23	electrostatic stabiliser, hydrogen bond donor
H	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
H	ARG120	electrostatic stabiliser, proton acceptor, proton donor
H	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
H	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

site_id	MCSA9
Number of Residues	6
Details	M-CSA 369

Chain	Residue	Details
I	LYS22	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor
I	ASN23	electrostatic stabiliser, hydrogen bond donor
I	CYS115	activator, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor, proton relay
I	ARG120	electrostatic stabiliser, proton acceptor, proton donor
I	ALA305	activator, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
I	ARG397	electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)