1A2N

STRUCTURE OF THE C115A MUTANT OF MURA COMPLEXED WITH THE FLUORINATED ANALOG OF THE REACTION TETRAHEDRAL INTERMEDIATE

Summary for 1A2N

Entry DOI	10.2210/pdb1a2n/pdb
Descriptor	UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE, URIDINE-DIPHOSPHATE-2(N-ACETYLGLUCOSAMINYL-3-FLUORO-2-PHOSPHONOOXY)PROPIONIC ACID (3 entities in total)
Functional Keywords	transferase, peptidoglycan synthesis, enolpyruvyl transferase, udp-n-acetylglucosamine
Biological source	Escherichia coli
Total number of polymer chains	1
Total formula weight	45632.86
Authors	Skarzynski, T. (deposition date: 1998-01-06, release date: 1998-04-29, Last modification date: 2023-08-02)
Primary citation	Skarzynski, T.,Kim, D.H.,Lees, W.J.,Walsh, C.T.,Duncan, K. Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant of MurA Biochemistry, 37:2572-2577, 1998 Cited by PubMed: 9485407 DOI: 10.1021/bi9722608 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation