2Z2C

MURA inhibited by unag-cnicin adduct

Summary for 2Z2C

• Entry DOI: 10.2210/pdb2z2c/pdb
• Related: 1A2N 1EJD 1NAW 1Q3G 1UAE 1YBG
• Descriptor: UDP-N-acetylglucosamine 1-carboxyvinyltransferase, URIDINE-5'-DIPHOSPHATE, 2-acetamido-3-O-[(2S,3S)-2-carboxy-3,4-dihydroxybutan-2-yl]-2-deoxy-alpha-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: peptidoglycan, transferase, udp-n-acetylglucosamine, cnicin, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Escherichia coli
• Total number of polymer chains: 4
• Total formula weight: 184386.40

Authors

Steinbach, A.,Skarzynski, T.,Scheidig, A.J.,Klein, C.D. (deposition date: 2007-05-17, release date: 2008-05-20, Last modification date: 2023-11-01)

• Primary citation: Steinbach, A.,Skarzynski, T.,Scheidig, A.J.,Klein, C.D.; The Antibacterial Target Enzyme Mura Synthesizes its Own Non-Covalent Suicide Inhibitor from the Natural Product Cnicin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.05 Å)