4DEN
Structural insightsinto potent, specific anti-HIV property of actinohivin; Crystal structure of actinohivin in complex with alpha(1-2) mannobiose moiety of high-mannose type glycan of gp120
Summary for 4DEN
Entry DOI | 10.2210/pdb4den/pdb |
Related | 3A07 |
Related PRD ID | PRD_900111 |
Descriptor | Actinohivin, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose, POTASSIUM ION, ... (4 entities in total) |
Functional Keywords | anti-hiv lectin, molecular recognition, high-mannose type glycan, antiviral protein |
Biological source | Actinomycete |
Total number of polymer chains | 1 |
Total formula weight | 13676.68 |
Authors | Hoque, M.M.,Suzuki, K.,Tsunoda, M.,Jiang, J.,Zhang, F.,Takahashi, A.,Naomi, O.,Zhang, X.,Sekiguchi, T.,Tanaka, H.,Omura, S.,Takenaka, A. (deposition date: 2012-01-20, release date: 2012-11-28, Last modification date: 2023-11-08) |
Primary citation | Hoque, M.M.,Suzuki, K.,Tsunoda, M.,Jiang, J.,Zhang, F.,Takahashi, A.,Ohbayashi, N.,Zhang, X.,Tanaka, H.,Omura, S.,Takenaka, A. Structural insights into the specific anti-HIV property of actinohivin: structure of its complex with the alpha(1–2)mannobiose moiety of gp120 Acta Crystallogr.,Sect.D, 68:1671-1679, 2012 Cited by PubMed: 23151632DOI: 10.1107/S0907444912040498 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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