4WOY
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![BU of 4woy by Molmil](/molmil-images/mine/4woy) | Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1 | 分子名称: | Mitochondrial dynamics protein MID49 | 著者 | Loson, O.C, Meng, S, Ngo, H.B, Liu, R, Kaiser, J.T, Chan, D.C. | 登録日 | 2014-10-17 | 公開日 | 2015-01-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure and functional analysis of MiD49, a receptor for the mitochondrial fission protein Drp1. Protein Sci., 24, 2015
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6E15
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![BU of 6e15 by Molmil](/molmil-images/mine/6e15) | Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD | 分子名称: | Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ... | 著者 | Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H. | 登録日 | 2018-07-09 | 公開日 | 2018-10-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (6.2 Å) | 主引用文献 | Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD. Nature, 562, 2018
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6QYW
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![BU of 6qyw by Molmil](/molmil-images/mine/6qyw) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - nisin ring A | 分子名称: | ILE-DBU-DAL-ILE-DHA-LEU-CYS-ALA | 著者 | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | 登録日 | 2019-03-09 | 公開日 | 2019-09-11 | 最終更新日 | 2019-10-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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2W0J
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![BU of 2w0j by Molmil](/molmil-images/mine/2w0j) | Crystal structure of Chk2 in complex with NSC 109555, a specific inhibitor | 分子名称: | 4,4'-DIACETYLDIPHENYLUREA-BIS(GUANYLHYDRAZONE), NITRATE ION, SERINE/THREONINE-PROTEIN KINASE CHK2 | 著者 | Lountos, G.T, Tropea, J.E, Zhang, D, Jobson, A.G, Pommier, Y, Shoemaker, R.H, Waugh, D.S. | 登録日 | 2008-08-18 | 公開日 | 2009-02-10 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal Structure of Checkpoint Kinase 2 in Complex with Nsc 109555, a Potent and Selective Inhibitor Protein Sci., 18, 2009
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8P3Z
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![BU of 8p3z by Molmil](/molmil-images/mine/8p3z) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 2 | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | 著者 | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | 登録日 | 2023-05-18 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | 主引用文献 | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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8P3Y
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![BU of 8p3y by Molmil](/molmil-images/mine/8p3y) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3 | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | 著者 | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | 登録日 | 2023-05-18 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.55 Å) | 主引用文献 | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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6QYV
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![BU of 6qyv by Molmil](/molmil-images/mine/6qyv) | Solution NMR of synthetic analogues of nisin and mutacin ring A and ring B - Mutacin I Ring A (Ser2, Ala5, Ala8) analogue | 分子名称: | PHE-SER-DAL-LEU-ALA-LEU-CYS-ALA | 著者 | Dickman, R, Mitchell, S.A, Figueiredo, A, Hansen, D.F, Tabor, A.B. | 登録日 | 2019-03-09 | 公開日 | 2019-09-11 | 最終更新日 | 2019-10-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular Recognition of Lipid II by Lantibiotics: Synthesis and Conformational Studies of Analogues of Nisin and Mutacin Rings A and B. J.Org.Chem., 84, 2019
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6M24
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![BU of 6m24 by Molmil](/molmil-images/mine/6m24) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-2 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-26 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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6M2J
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![BU of 6m2j by Molmil](/molmil-images/mine/6m2j) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-1 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-27 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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4YH3
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![BU of 4yh3 by Molmil](/molmil-images/mine/4yh3) | Crystal structure of human BRD4(1) in complex with 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19a) | 分子名称: | 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one, Bromodomain-containing protein 4 | 著者 | White, A, Lakshminarasimhan, D, Suto, R.K. | 登録日 | 2015-02-26 | 公開日 | 2016-01-13 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design. Bioorg.Med.Chem.Lett., 25, 2015
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6M2K
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![BU of 6m2k by Molmil](/molmil-images/mine/6m2k) | Uncommon structural features of rabbit MHC class I (RLA-A1) complexed with rabbit haemorrhagic disease virus (RHDV) derived peptide, VP60-10 | 分子名称: | Beta-2-microglobulin, RLA class I histocompatibility antigen, alpha chain 19-1, ... | 著者 | Zhang, Q.X, Liu, K.F, Yue, C, Zhang, D, Lu, D, Xiao, W.L, Liu, P.P, Zhao, Y.Z, Gao, G.L, Ding, C.M, Lyu, J.X, Liu, W.J. | 登録日 | 2020-02-27 | 公開日 | 2020-07-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1. J.Virol., 94, 2020
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7TV9
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![BU of 7tv9 by Molmil](/molmil-images/mine/7tv9) | HUMAN COMPLEMENT COMPONENT C3B IN COMPLEX WITH APL-1030 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, APL-1030 Nanofitin, Complement C3 beta chain, ... | 著者 | Fontano, E, Nadupalli, A, Lakshminarasimhan, D, White, A, Garlish, J, Cinier, M, Chevrel, A, Perrocheau, A, Eyerman, D, Orme, M, Kitten, O, Scheibler, L. | 登録日 | 2022-02-04 | 公開日 | 2022-03-30 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Discovery of APL-1030, a Novel, High-Affinity Nanofitin Inhibitor of C3-Mediated Complement Activation. Biomolecules, 12, 2022
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8P3X
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![BU of 8p3x by Molmil](/molmil-images/mine/8p3x) | Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 1 | 分子名称: | Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit | 著者 | Krieger, J.M, Zhang, D, Yamashita, K, Greger, I.H. | 登録日 | 2023-05-18 | 公開日 | 2023-08-30 | 最終更新日 | 2023-10-11 | 実験手法 | ELECTRON MICROSCOPY (3.36 Å) | 主引用文献 | Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor. Nature, 621, 2023
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6E4A
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![BU of 6e4a by Molmil](/molmil-images/mine/6e4a) | Crystal structure of human BRD4(1) in complex with CN750 | 分子名称: | 5-(4-{[(3-chlorophenyl)methyl]amino}-2-{4-[2-(dimethylamino)ethyl]piperazin-1-yl}quinazolin-6-yl)-1-methylpyridin-2(1H)-one, Bromodomain-containing protein 4, GLYCEROL | 著者 | Fontano, E, White, A, Lakshminarasimhan, D, Suto, R.K. | 登録日 | 2018-07-17 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.26 Å) | 主引用文献 | Discovery and lead identification of quinazoline-based BRD4 inhibitors. Bioorg. Med. Chem. Lett., 28, 2018
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6E14
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![BU of 6e14 by Molmil](/molmil-images/mine/6e14) | Handover mechanism of the growing pilus by the bacterial outer membrane usher FimD | 分子名称: | Chaperone protein FimC, Fimbrial biogenesis outer membrane usher protein, Protein FimF, ... | 著者 | Du, M, Yuan, Z, Yu, H, Henderson, N, Sarowar, S, Zhao, G, Werneburg, G.T, Thanassi, D.G, Li, H. | 登録日 | 2018-07-09 | 公開日 | 2018-10-17 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Handover mechanism of the growing pilus by the bacterial outer-membrane usher FimD. Nature, 562, 2018
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6VQN
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![BU of 6vqn by Molmil](/molmil-images/mine/6vqn) | Co-crystal structure of human PD-L1 complexed with Compound A | 分子名称: | N,N'-(2,2'-dimethyl[1,1'-biphenyl]-3,3'-diyl)bis(5-{[(2-hydroxyethyl)amino]methyl}pyridine-2-carboxamide), Programmed cell death 1 ligand 1 | 著者 | White, A, Lakshminarasimhan, D, Leo, C, Suto, R.K. | 登録日 | 2020-02-05 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Checkpoint inhibition through small molecule-induced internalization of programmed death-ligand 1. Nat Commun, 12, 2021
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6VJV
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![BU of 6vjv by Molmil](/molmil-images/mine/6vjv) | Crystal structure of the Prochlorococcus phage (myovirus P-SSM2) ferredoxin at 1.6 Angstroms | 分子名称: | ACETATE ION, FE2/S2 (INORGANIC) CLUSTER, Ferredoxin, ... | 著者 | Olmos Jr, J.L, Campbell, I.J, Miller, M.D, Xu, W, Kahanda, D, Atkinson, J.T, Sparks, N, Bennett, G.N, Silberg, J.J, Phillips Jr, G.N. | 登録日 | 2020-01-17 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Prochlorococcusphage ferredoxin: structural characterization and electron transfer to cyanobacterial sulfite reductases. J.Biol.Chem., 295, 2020
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6K7T
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![BU of 6k7t by Molmil](/molmil-images/mine/6k7t) | Crystal structure of bat (Pteropus Alecto) MHC class I Ptal-N*01:01 in complex with Hendra virus-derived peptide HeV1--human beta-2 microglobulin | 分子名称: | Beta-2-microglobulin, HeV1, MHC class I antigen | 著者 | Lu, D, Liu, K.F, Zhang, D, Yue, C, Lu, Q, Cheng, H, Chai, Y, Qi, J.X, Gao, F.G, Liu, W.J. | 登録日 | 2019-06-08 | 公開日 | 2019-11-06 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Peptide presentation by bat MHC class I provides new insight into the antiviral immunity of bats. Plos Biol., 17, 2019
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7XF3
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![BU of 7xf3 by Molmil](/molmil-images/mine/7xf3) | The structure of HLA-B*1501/BM58-66AF9 | 分子名称: | 9-mer peptide from Matrix protein 1, Beta-2-microglobulin, MHC class I antigen | 著者 | Zhao, Y.Z, Xiao, W.L, Wu, Y.N, Fan, W.F, Yue, C, Zhang, Q.X, Zhang, D.N, Yuan, X.J, Yao, S.J, Liu, S, Li, M, Wang, P.Y, Zhang, H.J, Zhang, J, Zhao, M, Zheng, X.Q, Liu, W.J, Gao, G.F, Liu, W.L. | 登録日 | 2022-03-31 | 公開日 | 2023-02-08 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | Parallel T Cell Immunogenic Regions in Influenza B and A Viruses with Distinct Nuclear Export Signal Functions: The Balance between Viral Life Cycle and Immune Escape. J Immunol., 210, 2023
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3P2M
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![BU of 3p2m by Molmil](/molmil-images/mine/3p2m) | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis | 分子名称: | POSSIBLE HYDROLASE | 著者 | Zheng, X.D, Guo, J, Xu, L, Li, H, Zhang, D, Zhang, K, Sun, F, Wen, T, Liu, S, Pang, H. | 登録日 | 2010-10-03 | 公開日 | 2011-07-06 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of a Novel Esterase Rv0045c from Mycobacterium tuberculosis Plos One, 6, 2011
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6DEY
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8SSK
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![BU of 8ssk by Molmil](/molmil-images/mine/8ssk) | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains | 分子名称: | ACETATE ION, CALCIUM ION, Contact-dependent inhibitor A, ... | 著者 | Cuthbert, B.J, Goulding, C.W, Hayes, C.S, Nhan, D.Q. | 登録日 | 2023-05-08 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains To Be Published
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8SSM
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7Y78
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![BU of 7y78 by Molmil](/molmil-images/mine/7y78) | Crystal structure of Cry78Aa | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, Toxin | 著者 | Cao, B.B, Nie, Y.F, Wang, N.C, Guan, Z.Y, Zhang, D.L, Zhang, J. | 登録日 | 2022-06-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | The crystal structure of Cry78Aa from Bacillus thuringiensis provides insights into its insecticidal activity. Commun Biol, 5, 2022
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7DWV
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![BU of 7dwv by Molmil](/molmil-images/mine/7dwv) | Cryo-EM structure of amyloid fibril formed by familial prion disease-related mutation E196K | 分子名称: | Major prion protein | 著者 | Wang, L.Q, Zhao, K, Yuan, H.Y, Li, X.N, Dang, H.B, Ma, Y.Y, Wang, Q, Wang, C, Sun, Y.P, Chen, J, Li, D, Zhang, D.L, Yin, P, Liu, C, Liang, Y. | 登録日 | 2021-01-18 | 公開日 | 2021-10-13 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Genetic prion disease-related mutation E196K displays a novel amyloid fibril structure revealed by cryo-EM. Sci Adv, 7, 2021
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