8P3Y

Homomeric GluA2 flip R/G-edited Q/R-edited F231A mutant in tandem with TARP gamma-2, desensitized conformation 3

Summary for 8P3Y

• Entry DOI: 10.2210/pdb8p3y/pdb
• EMDB information: 17399
• Descriptor: Glutamate receptor 2, Voltage-dependent calcium channel gamma-2 subunit (2 entities in total)
• Functional Keywords: ampa-type glutamate neurotransmitter receptor, auxiliary subunit complex, agonist, desensitized, membrane protein
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 8
• Total formula weight: 538377.67

Authors

Krieger, J.M.,Zhang, D.,Yamashita, K.,Greger, I.H. (deposition date: 2023-05-18, release date: 2023-08-30, Last modification date: 2023-10-11)

• Primary citation: Zhang, D.,Ivica, J.,Krieger, J.M.,Ho, H.,Yamashita, K.,Stockwell, I.,Baradaran, R.,Cais, O.,Greger, I.H.; Structural mobility tunes signalling of the GluA1 AMPA glutamate receptor.; Nature, 621:877-882, 2023; PubMed: 37704721; DOI: 10.1038/s41586-023-06528-0

Experimental method

ELECTRON MICROSCOPY (3.55 Å)