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PDB: 27 件

7MDS
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Crystal structure of AtDHDPS1 in complex with MBDTA-2
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, CHLORIDE ION, ...
著者Hall, C.J, Soares da Costa, T.P, Panjikar, S.
登録日2021-04-06
公開日2021-08-04
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.295 Å)
主引用文献Towards novel herbicide modes of action by inhibiting lysine biosynthesis in plants.
Elife, 10, 2021
3TCM
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BU of 3tcm by Molmil
Crystal Structure of Alanine Aminotransferase from Hordeum vulgare
分子名称: Alanine aminotransferase 2, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE
著者Rydel, T.J, Sturman, E.J, Halls, C, Chen, S, Zeng, J, Evdokimov, A, Duff, S.M.G.
登録日2011-08-09
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献The Enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure.
Arch.Biochem.Biophys., 528, 2012
6OVB
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BU of 6ovb by Molmil
Crystal structure of a Bacillus thuringiensis Cry1Da tryptic core variant
分子名称: Active core crystal toxin protein 1D
著者Rydel, T.J, Halls, C, Evdokimov, A.G, Beishir, S.C.
登録日2019-05-07
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.611 Å)
主引用文献Bacillus thuringiensis Cry1Da_7 and Cry1B.868 Protein Interactions with Novel Receptors Allow Control of Resistant Fall Armyworms, Spodoptera frugiperda (J.E. Smith).
Appl.Environ.Microbiol., 85, 2019
6D3J
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BU of 6d3j by Molmil
FT_T dioxygenase holoenzyme
分子名称: 2-OXOGLUTARIC ACID, COBALT (II) ION, FT_T dioxygenase
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D3M
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FT_T dioxygenase with bound quizalofop
分子名称: (2R)-2-{4-[(6-chloroquinoxalin-2-yl)oxy]phenoxy}propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D3I
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ftv7 dioxygenase with 2,4-D bound
分子名称: (2,4-DICHLOROPHENOXY)ACETIC ACID, 2-OXOGLUTARIC ACID, COBALT (II) ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.196 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D3H
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BU of 6d3h by Molmil
FT_T dioxygenase with bound dichlorprop
分子名称: (2R)-2-(2,4-dichlorophenoxy)propanoic acid, 2-OXOGLUTARIC ACID, CHLORIDE ION, ...
著者Rydel, T.J, Halls, C.E.
登録日2018-04-16
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6D1O
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BU of 6d1o by Molmil
FT_5 dioxygenase apoenzyme
分子名称: (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase
著者Rydel, T.J, Halls, C.E.
登録日2018-04-12
公開日2018-08-15
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops.
Pest Manag. Sci., 75, 2019
6VVI
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BU of 6vvi by Molmil
Arabidopsis thaliana dihydrodipicolinate synthase isoform 1 (DHDPS1)
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, GLYCEROL, ...
著者Lee, M, Hall, C.J.
登録日2020-02-18
公開日2021-02-24
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.145 Å)
主引用文献Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.
Febs J., 288, 2021
6VVH
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Arabidopsis thaliana dihydrodipicolinate synthase isoform 1 (DHDPS1) in complex with lysine
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-hydroxy-tetrahydrodipicolinate synthase 1, chloroplastic, ...
著者Lee, M, Hall, C.J.
登録日2020-02-18
公開日2021-02-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.792 Å)
主引用文献Differential lysine-mediated allosteric regulation of plant dihydrodipicolinate synthase isoforms.
Febs J., 288, 2021
6P90
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Crystal structure of PaDHDPS2-H56Q mutant
分子名称: 4-hydroxy-tetrahydrodipicolinate synthase, CHLORIDE ION, GLYCEROL
著者Impey, R.E, Panjikar, S, Hall, C.J, Bock, L.J, Sutton, J.M, Perugini, M.A, Soares da Costa, T.P.
登録日2019-06-08
公開日2019-08-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Identification of two dihydrodipicolinate synthase isoforms from Pseudomonas aeruginosa that differ in allosteric regulation.
Febs J., 287, 2020
8EZ0
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BU of 8ez0 by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Symmetric conformation
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
8EYX
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BU of 8eyx by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S; denoted as IR-3CS) Asymmetric conformation 1
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
8EYY
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BU of 8eyy by Molmil
Cryo-EM structure of 4 insulins bound full-length mouse IR mutant with physically decoupled alpha CTs (C684S/C685S/C687S, denoted as IR-3CS) Asymmetric conformation 2
分子名称: Insulin, Insulin receptor
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-29
公開日2022-11-09
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
8EYR
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BU of 8eyr by Molmil
Cryo-EM structure of two IGF1 bound full-length mouse IGF1R mutant (four glycine residues inserted in the alpha-CT; IGF1R-P674G4): symmetric conformation
分子名称: Insulin-like growth factor 1 receptor, Insulin-like growth factor I
著者Li, J, Wu, J.Y, Hall, C, Bai, X.C, Choi, E.
登録日2022-10-28
公開日2022-11-09
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular basis for the role of disulfide-linked alpha CTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
Elife, 11, 2022
8SBD
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BU of 8sbd by Molmil
Cryo-EM structure of insulin amyloid-like fibril that is composed of two antiparallel protofilaments
分子名称: Insulin A chain, Insulin B chain
著者Wang, L.W, Hall, C, Uchikawa, E, Chen, D.L, Choi, E, Zhang, X.W, Bai, X.C.
登録日2023-04-03
公開日2023-08-30
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of insulin fibrillation.
Sci Adv, 9, 2023
7TYJ
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BU of 7tyj by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was focused on one of two halves with C1 symmetry applied
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
7TYK
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BU of 7tyk by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in apo-state captured at pH 7. The 3D refinement was applied with C2 symmetry
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2023-05-31
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
7TYM
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BU of 7tym by Molmil
Cryo-EM Structure of insulin receptor-related receptor (IRR) in active-state captured at pH 9. The 3D refinement was applied with C2 symmetry
分子名称: Insulin receptor-related protein
著者Wang, L.W, Hall, C, Li, J, Choi, E, Bai, X.C.
登録日2022-02-13
公開日2023-02-15
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of the alkaline pH-dependent activation of insulin receptor-related receptor.
Nat.Struct.Mol.Biol., 30, 2023
2KH2
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BU of 2kh2 by Molmil
Solution structure of a scFv-IL-1B complex
分子名称: Interleukin-1 beta, scFv
著者Wilkinson, I.C, Hall, C.J, Veverka, V, Muskett, F.W, Stephens, P.E, Taylor, R.J, Henry, A.J, Carr, M.D.
登録日2009-03-23
公開日2009-09-08
最終更新日2024-10-30
実験手法SOLUTION NMR
主引用文献High resolution NMR-based model for the structure of a scFv-IL-1beta complex: potential for NMR as a key tool in therapeutic antibody design and development.
J.Biol.Chem., 284, 2009
8DTM
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BU of 8dtm by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 component 2
分子名称: Insulin mimetic peptide S597 component 2, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-26
公開日2022-09-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
8DTL
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BU of 8dtl by Molmil
Cryo-EM structure of insulin receptor (IR) bound with S597 peptide
分子名称: Insulin mimetic peptide S597, Insulin receptor
著者Park, J, Li, J, Mayer, J.P, Ball, K.A, Wu, J.Y, Hall, C, Accili, D, Stowell, M.H.B, Bai, X.C, Choi, E.
登録日2022-07-25
公開日2022-09-07
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Activation of the insulin receptor by an insulin mimetic peptide.
Nat Commun, 13, 2022
8U4B
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BU of 8u4b by Molmil
Cryo-EM structure of long form insulin receptor (IR-B) in the apo state
分子名称: Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2023-09-10
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8VJB
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Cryo-EM structure of short form insulin receptor (IR-A) with four IGF2 bound, symmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-04-03
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024
8VJC
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Cryo-EM structure of short form insulin receptor (IR-A) with three IGF2 bound, asymmetric conformation.
分子名称: Insulin-like growth factor II, Isoform Short of Insulin receptor
著者An, W, Hall, C, Li, J, Huang, A, Wu, J, Park, J, Bai, X.C, Choi, E.
登録日2024-01-06
公開日2024-03-27
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Activation of the insulin receptor by insulin-like growth factor 2.
Nat Commun, 15, 2024

 

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