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PDB: 183 results

3H84
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BU of 3h84 by Molmil
Crystal structure of GET3
Descriptor: ATPase GET3, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Hu, J, Li, J, Qian, X, Sha, B.
Deposit date:2009-04-28
Release date:2009-12-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion.
Plos One, 4, 2009
9B8Y
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BU of 9b8y by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and decavanadate at 37 degrees Celsius
Descriptor: CALCIUM ION, DECAVANADATE, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
6DWB
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BU of 6dwb by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome needle filament
Descriptor: Protein PrgI
Authors:Hu, J, Hong, C, Worrall, L.J, Vuckovic, M, Yu, Z, Strynadka, N.C.J.
Deposit date:2018-06-26
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV3
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BU of 6dv3 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
4TZ7
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BU of 4tz7 by Molmil
Crystal structure of type I phosphatidylinositol 4-phosphate 5-kinase alpha from Zebrafish
Descriptor: Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
Authors:Hu, J, Qin, Y, Wang, J, Li, L, Wu, D, Ha, Y.
Deposit date:2014-07-09
Release date:2015-09-02
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.31 Å)
Cite:Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.
Nat Commun, 6, 2015
8F3D
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BU of 8f3d by Molmil
3-methylcrotonyl-CoA carboxylase in filament, beta-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase alpha-subunit, 3-methylcrotonyl-CoA carboxylase beta-subunit, 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-09
Release date:2023-01-11
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
6PEP
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BU of 6pep by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgIJ from the Salmonella SPI-1 injectisome needle complex
Descriptor: Protein InvG, Protein PrgH, Protein PrgI, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEE
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BU of 6pee by Molmil
InvG secretin domain beta-barrel from Salmonella SPI-1 injectisome NC-base
Descriptor: LAURYL DIMETHYLAMINE-N-OXIDE, Protein InvG
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.42 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6PEM
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BU of 6pem by Molmil
Focussed refinement of InvGN0N1:SpaPQR:PrgHK from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-06-20
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q15
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BU of 6q15 by Molmil
Structure of the Salmonella SPI-1 injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (5.15 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q14
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BU of 6q14 by Molmil
Structure of the Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
6Q16
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BU of 6q16 by Molmil
Focussed refinement of InvGN0N1:PrgHK:SpaPQR:PrgIJ from Salmonella SPI-1 injectisome NC-base
Descriptor: Lipoprotein PrgK, Protein InvG, Protein PrgH, ...
Authors:Hu, J, Worrall, L.J, Strynadka, N.C.J.
Deposit date:2019-08-02
Release date:2019-10-23
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:T3S injectisome needle complex structures in four distinct states reveal the basis of membrane coupling and assembly.
Nat Microbiol, 4, 2019
8F41
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BU of 8f41 by Molmil
3-methylcrotonyl-CoA carboxylase in filament, alpha-subunit centered
Descriptor: 3-methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit, ...
Authors:Hu, J.J, Lee, J.K.J, Liu, Y.T, Yu, C, Huang, L, Afasizheva, I, Afasizhev, R, Zhou, Z.H.
Deposit date:2022-11-10
Release date:2023-01-11
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Discovery, structure, and function of filamentous 3-methylcrotonyl-CoA carboxylase.
Structure, 31, 2023
6DV6
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BU of 6dv6 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG (residues 176-end) in the open gate state
Descriptor: Protein InvG
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DUZ
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BU of 6duz by Molmil
Structure of the periplasmic domains of PrgH and PrgK from the assembled Salmonella type III secretion injectisome needle complex
Descriptor: Lipoprotein PrgK, Protein PrgH
Authors:Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
Deposit date:2018-06-22
Release date:2018-10-03
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
1RQQ
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BU of 1rqq by Molmil
Crystal Structure of the Insulin Receptor Kinase in Complex with the SH2 Domain of APS
Descriptor: BISUBSTRATE INHIBITOR, Insulin receptor, MANGANESE (II) ION, ...
Authors:Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
Deposit date:2003-12-06
Release date:2003-12-30
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
3IO3
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BU of 3io3 by Molmil
GEt3 with ADP from D. Hansenii in Closed form
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DEHA2D07832p, GLYCEROL, ...
Authors:Hu, J, Li, J, Qian, X, Sha, B.
Deposit date:2009-08-13
Release date:2009-12-22
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structures of yeast Get3 suggest a mechanism for tail-anchored protein membrane insertion
Plos One, 4, 2009
1RPY
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BU of 1rpy by Molmil
CRYSTAL STRUCTURE OF THE DIMERIC SH2 DOMAIN OF APS
Descriptor: SULFATE ION, adaptor protein APS
Authors:Hu, J, Liu, J, Ghirlando, R, Saltiel, A.R, Hubbard, S.R.
Deposit date:2003-12-03
Release date:2003-12-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for recruitment of the adaptor protein APS to the activated insulin receptor.
Mol.Cell, 12, 2003
1YVH
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BU of 1yvh by Molmil
Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide
Descriptor: 13-mer fragment of SH2 and PH domain-containing adapter protein APS, CBL E3 ubiquitin protein ligase, MAGNESIUM ION
Authors:Hu, J, Hubbard, S.R.
Deposit date:2005-02-15
Release date:2005-03-08
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Characterization of a Novel Cbl Phosphotyrosine Recognition Motif in the APS Family of Adapter Proteins
J.Biol.Chem., 280, 2005
2AXL
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BU of 2axl by Molmil
Solution structure of a multifunctional DNA- and protein-binding domain of human Werner syndrome protein
Descriptor: Werner syndrome
Authors:Hu, J.-S, Feng, H, Zeng, W, Lin, G.-X, Xi, X.G.
Deposit date:2005-09-05
Release date:2005-12-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein.
Proc.Natl.Acad.Sci.Usa, 102, 2005
5YAK
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BU of 5yak by Molmil
The crystal structure of human IYD Thr239 mutant with ligand 3-Fluorotyrosine (F-Tyr)
Descriptor: 3-FLUOROTYROSINE, FLAVIN MONONUCLEOTIDE, Iodotyrosine deiodinase 1
Authors:Hu, J.M, Rokita, S.E, Schlessman, J.
Deposit date:2017-09-01
Release date:2018-08-08
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Redox control of iodotyrosine deiodinase
Protein Sci., 28, 2019
8I99
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BU of 8i99 by Molmil
N-carbamoyl-D-amino-acid hydrolase mutant - M4Th3
Descriptor: N-carbamoyl-D-amino-acid hydrolase
Authors:Hu, J.M, Ni, Y, Xu, G.C.
Deposit date:2023-02-06
Release date:2023-03-22
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan.
J.Agric.Food Chem., 71, 2023
9B90
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BU of 9b90 by Molmil
Cryo-EM structure of the human TRPM4 channel in complex with calcium and ATP at 37 degrees Celsius
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B8W
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BU of 9b8w by Molmil
Cryo-EM structure of the human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-15
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024
9B94
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BU of 9b94 by Molmil
Cryo-EM structure of the E396A mutant of human TRPM4 in complex with calcium at 37 degrees Celsius
Descriptor: CALCIUM ION, Transient receptor potential cation channel subfamily M member 4
Authors:Hu, J, Lu, W, Du, J.
Deposit date:2024-04-01
Release date:2024-05-22
Last modified:2024-06-26
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Physiological temperature drives TRPM4 ligand recognition and gating.
Nature, 630, 2024

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