5YAK

The crystal structure of human IYD Thr239 mutant with ligand 3-Fluorotyrosine (F-Tyr)

Summary for 5YAK

Entry DOI	10.2210/pdb5yak/pdb
Descriptor	Iodotyrosine deiodinase 1, FLAVIN MONONUCLEOTIDE, 3-FLUOROTYROSINE, ... (4 entities in total)
Functional Keywords	hiyd, fmn, mft, t239a mutant, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	6
Total formula weight	187160.84
Authors	Hu, J.M.,Rokita, S.E.,Schlessman, J. (deposition date: 2017-09-01, release date: 2018-08-08, Last modification date: 2023-11-22)
Primary citation	Hu, J.,Su, Q.,Schlessman, J.L.,Rokita, S.E. Redox control of iodotyrosine deiodinase Protein Sci., 28:68-78, 2019 Cited by PubMed: 30052294 DOI: 10.1002/pro.3479 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation