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PDB: 16 件
4RIK
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BU of 4rik by Molmil
Amyloid forming segment, AVVTGVTAV, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 69-77
分子名称: Alpha-synuclein
著者Guenther, E.L, Sawaya, M.R, Ivanova, M, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.854 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
6CFH
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BU of 6cfh by Molmil
SWGMMGMLASQ segment from the low complexity domain of TDP-43
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Rodriguez, J.A, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-15
公開日2018-05-23
最終更新日2021-10-13
実験手法ELECTRON CRYSTALLOGRAPHY (1.5 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CB9
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BU of 6cb9 by Molmil
Segment AALQSS from the low complexity domain of TDP-43, residues 328-333
分子名称: AALQSS
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-02
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CEW
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BU of 6cew by Molmil
Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326
分子名称: AMMAAA
著者Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-12
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
6CF4
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BU of 6cf4 by Molmil
Segment NFGTFS, with familial mutation A315T and phosphorylated threonine, from the low complexity domain of TDP-43, residues 312-317
分子名称: NFGTFS
著者Guenther, E.L, Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S.
登録日2018-02-13
公開日2018-05-23
最終更新日2021-06-30
実験手法ELECTRON CRYSTALLOGRAPHY (0.75 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WIA
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BU of 5wia by Molmil
Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-18
公開日2018-04-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.002 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5W50
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BU of 5w50 by Molmil
Crystal structure of the segment, LIIKGI, from the RRM2 of TDP-43, residues 248-253
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S.
登録日2017-06-13
公開日2018-02-21
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5W7V
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BU of 5w7v by Molmil
CryoEM structure of the segment, DLIIKGISVHI, assembled into a triple-helical fibril
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Ge, P, Eisenberg, D.S.
登録日2017-06-20
公開日2018-03-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WKD
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BU of 5wkd by Molmil
Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-25
公開日2018-04-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WHN
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BU of 5whn by Molmil
Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317
分子名称: Segment of TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-17
公開日2018-04-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WHP
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BU of 5whp by Molmil
Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: Segment of TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-17
公開日2018-05-23
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5WIQ
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BU of 5wiq by Molmil
Crystal structure of the segment, GFNGGFG, from the low complexity domain of TDP-43, residues 396-402
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Eisenberg, D.S.
登録日2017-07-19
公開日2018-04-18
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
5W52
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BU of 5w52 by Molmil
MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-06-13
公開日2018-02-21
最終更新日2024-04-03
実験手法ELECTRON CRYSTALLOGRAPHY (1.4 Å)
主引用文献Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2.
Nat. Struct. Mol. Biol., 25, 2018
5WKB
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BU of 5wkb by Molmil
MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317
分子名称: TAR DNA-binding protein 43
著者Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S.
登録日2017-07-24
公開日2018-05-23
最終更新日2024-03-13
実験手法ELECTRON CRYSTALLOGRAPHY (1 Å)
主引用文献Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation.
Nat. Struct. Mol. Biol., 25, 2018
4RIL
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BU of 4ril by Molmil
Structure of the amyloid forming segment, GAVVTGVTAVA, from the NAC domain of Parkinson's disease protein alpha-synuclein, residues 68-78, determined by electron diffraction
分子名称: Alpha-synuclein
著者Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S.
登録日2014-10-06
公開日2015-08-26
最終更新日2023-09-20
実験手法ELECTRON CRYSTALLOGRAPHY (1.43 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015
4ZNN
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BU of 4znn by Molmil
MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56
分子名称: Alpha-synuclein
著者Rodriguez, J.A, Ivanova, M, Sawaya, M.R, Cascio, D, Reyes, F, Shi, D, Johnson, L, Guenther, E, Sangwan, S, Hattne, J, Nannenga, B, Brewster, A.S, Messerschmidt, M, Boutet, S, Sauter, N.K, Gonen, T, Eisenberg, D.S.
登録日2015-05-05
公開日2015-09-09
最終更新日2024-03-06
実験手法ELECTRON CRYSTALLOGRAPHY (1.41 Å)
主引用文献Structure of the toxic core of alpha-synuclein from invisible crystals.
Nature, 525, 2015

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