5W52
MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257
Summary for 5W52
| Entry DOI | 10.2210/pdb5w52/pdb |
| Related | 5W50 |
| EMDB information | 8765 |
| Descriptor | TAR DNA-binding protein 43 (1 entity in total) |
| Functional Keywords | amyloid, steric zipper, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 1209.48 |
| Authors | Guenther, E.L.,Sawaya, M.R.,Cascio, D.,Eisenberg, D.S. (deposition date: 2017-06-13, release date: 2018-02-21, Last modification date: 2024-04-03) |
| Primary citation | Guenther, E.L.,Ge, P.,Trinh, H.,Sawaya, M.R.,Cascio, D.,Boyer, D.R.,Gonen, T.,Zhou, Z.H.,Eisenberg, D.S. Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25:311-319, 2018 Cited by PubMed: 29531287DOI: 10.1038/s41594-018-0045-5 PDB entries with the same primary citation |
| Experimental method | ELECTRON CRYSTALLOGRAPHY (1.4 Å) |
Structure validation
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