4ZNN
MicroED structure of the segment, GVVHGVTTVA, from the A53T familial mutant of Parkinson's disease protein, alpha-synuclein residues 47-56
Summary for 4ZNN
Entry DOI | 10.2210/pdb4znn/pdb |
Related | 4RIL |
EMDB information | 3001 |
Descriptor | Alpha-synuclein (2 entities in total) |
Functional Keywords | amyloid, alpha-synuclein, parkinson's disease, toxic core, nacore, lipid binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 940.07 |
Authors | Rodriguez, J.A.,Ivanova, M.,Sawaya, M.R.,Cascio, D.,Reyes, F.,Shi, D.,Johnson, L.,Guenther, E.,Sangwan, S.,Hattne, J.,Nannenga, B.,Brewster, A.S.,Messerschmidt, M.,Boutet, S.,Sauter, N.K.,Gonen, T.,Eisenberg, D.S. (deposition date: 2015-05-05, release date: 2015-09-09, Last modification date: 2024-03-06) |
Primary citation | Rodriguez, J.A.,Ivanova, M.I.,Sawaya, M.R.,Cascio, D.,Reyes, F.E.,Shi, D.,Sangwan, S.,Guenther, E.L.,Johnson, L.M.,Zhang, M.,Jiang, L.,Arbing, M.A.,Nannenga, B.L.,Hattne, J.,Whitelegge, J.,Brewster, A.S.,Messerschmidt, M.,Boutet, S.,Sauter, N.K.,Gonen, T.,Eisenberg, D.S. Structure of the toxic core of alpha-synuclein from invisible crystals. Nature, 525:486-490, 2015 Cited by PubMed: 26352473DOI: 10.1038/nature15368 PDB entries with the same primary citation |
Experimental method | ELECTRON CRYSTALLOGRAPHY (1.41 Å) |
Structure validation
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