1MQW
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![BU of 1mqw by Molmil](/molmil-images/mine/1mqw) | Structure of the MT-ADPRase in complex with three Mn2+ ions and AMPCPR, a Nudix enzyme | 分子名称: | ADPR pyrophosphatase, ALPHA-BETA METHYLENE ADP-RIBOSE, MANGANESE (II) ION | 著者 | Kang, L.-W, Gabelli, S.B, Bianchet, M.A, Cunningham, J.E, O'Handley, S.F, Amzel, L.M. | 登録日 | 2002-09-17 | 公開日 | 2003-08-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11, 2003
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2BRA
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![BU of 2bra by Molmil](/molmil-images/mine/2bra) | Structure of N-Terminal FAD Binding motif of mouse MICAL | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, NEDD9 INTERACTING PROTEIN WITH CALPONIN HOMOLOGY AND LIM DOMAINS | 著者 | Nadella, M, Bianchet, M.A, Gabelli, S.B, Amzel, L.M. | 登録日 | 2005-05-04 | 公開日 | 2005-11-01 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and activity of the axon guidance protein MICAL. Proc. Natl. Acad. Sci. U.S.A., 102, 2005
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7STF
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![BU of 7stf by Molmil](/molmil-images/mine/7stf) | Structure of KRAS G12V/HLA-A*03:01 in complex with antibody fragment V2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A alpha chain, ... | 著者 | Wright, K.M, Gabelli, S.B, Miller, M. | 登録日 | 2021-11-12 | 公開日 | 2023-05-31 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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8DVG
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![BU of 8dvg by Molmil](/molmil-images/mine/8dvg) | Structure of KRAS WT(7-16)-HLA-A*03:01 | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, HLA class I histocompatibility antigen, ... | 著者 | Wright, K.M, Miller, M, Gabelli, S.B. | 登録日 | 2022-07-28 | 公開日 | 2023-07-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.594 Å) | 主引用文献 | Hydrophobic interactions dominate the recognition of a KRAS G12V neoantigen. Nat Commun, 14, 2023
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8STL
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![BU of 8stl by Molmil](/molmil-images/mine/8stl) | Crystal Structure of Nanobody PIK3_Nb16 against wild-type PI3Kalpha | 分子名称: | Nanobody PIK3_Nb16, SULFATE ION | 著者 | Nwafor, J.N, Srinivasan, L, Chen, Z, Gabelli, S.B, Iheanacho, A, Alzogaray, V, Klinke, S. | 登録日 | 2023-05-10 | 公開日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Development of isoform specific nanobodies for Class I PI3Ks To be published
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7U1B
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![BU of 7u1b by Molmil](/molmil-images/mine/7u1b) | |
7UDA
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![BU of 7uda by Molmil](/molmil-images/mine/7uda) | Structure of the EstG | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Beta-lactamase domain-containing protein, SODIUM ION | 著者 | Chen, Z, Gabelli, S.B. | 登録日 | 2022-03-18 | 公開日 | 2023-01-11 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | 主引用文献 | EstG is a novel esterase required for cell envelope integrity in Caulobacter. Curr.Biol., 33, 2023
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1N8Y
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![BU of 1n8y by Molmil](/molmil-images/mine/1n8y) | Crystal structure of the extracellular region of rat HER2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, protooncoprotein | 著者 | Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J. | 登録日 | 2002-11-21 | 公開日 | 2003-02-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Extracellular Region of HER2 Alone and in complex with the Herceptin Fab Nature, 421, 2003
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1N8Z
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![BU of 1n8z by Molmil](/molmil-images/mine/1n8z) | Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Herceptin Fab (antibody) - heavy chain, Herceptin Fab (antibody) - light chain, ... | 著者 | Cho, H.-S, Mason, K, Ramyar, K.X, Stanley, A.M, Gabelli, S.B, Denney Jr, D.W, Leahy, D.J. | 登録日 | 2002-11-21 | 公開日 | 2003-02-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Structure of the Extracellular Region of HER2 Alone and in Complex with the Herceptin Fab Nature, 421, 2003
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4K10
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![BU of 4k10 by Molmil](/molmil-images/mine/4k10) | Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM and Mg2+ | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-FLUORO-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, ACETATE ION, ... | 著者 | Aripirala, S, Gabelli, S, Amzel, L.M. | 登録日 | 2013-04-04 | 公開日 | 2014-04-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr.,Sect.D, 70, 2014
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4JZB
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![BU of 4jzb by Molmil](/molmil-images/mine/4jzb) | Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)-3-PHENYLPYRIDINIUM, IPP and Ca2+ | 分子名称: | 1-(2-hydroxy-2,2-diphosphonoethyl)-3-phenylpyridinium, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ... | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S. | 登録日 | 2013-04-02 | 公開日 | 2014-02-12 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr.,Sect.D, 70, 2014
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7UTT
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![BU of 7utt by Molmil](/molmil-images/mine/7utt) | |
4JZX
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![BU of 4jzx by Molmil](/molmil-images/mine/4jzx) | Crystal Structure of Leshmaniasis major Farnesyl diphosphate synthase in complex with 3-BUTYL-1-(2,2-DIPHOSPHONOETHYL)PYRIDINIUM, IPP and Ca2+ | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, 3-butyl-1-(2,2-diphosphonoethyl)pyridinium, CALCIUM ION, ... | 著者 | Aripirala, S, Gabelli, S, Amzel, L.M. | 登録日 | 2013-04-03 | 公開日 | 2014-03-05 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and thermodynamic basis of the inhibition of Leishmania major farnesyl diphosphate synthase by nitrogen-containing bisphosphonates. Acta Crystallogr.,Sect.D, 70, 2014
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6B09
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6NCI
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![BU of 6nci by Molmil](/molmil-images/mine/6nci) | Crystal structure of CDP-Chase: Vector data collection | 分子名称: | D-ribose, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | 著者 | Miller, M.S, Shi, W, Gabelli, S.B. | 登録日 | 2018-12-11 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
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6NCH
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![BU of 6nch by Molmil](/molmil-images/mine/6nch) | Crystal structure of CDP-Chase: Raster data collection | 分子名称: | D-ribose, PHOSPHATE ION, Phosphohydrolase (MutT/nudix family protein), ... | 著者 | Miller, M.S, Shi, W, Gabelli, S.B. | 登録日 | 2018-12-11 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
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6NCT
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![BU of 6nct by Molmil](/molmil-images/mine/6nct) | Structure of p110alpha/niSH2 - vector data collection | 分子名称: | Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, SULFATE ION, ... | 著者 | Miller, M.S, Maheshwari, S, Amzel, L.M, Gabelli, S.B. | 登録日 | 2018-12-12 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
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6NCK
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![BU of 6nck by Molmil](/molmil-images/mine/6nck) | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) | 分子名称: | COPPER (II) ION, NICKEL (II) ION, Peptidyl-glycine alpha-amidating monooxygenase | 著者 | Miller, M.S, Maheshwari, S, Gabelli, S.B. | 登録日 | 2018-12-11 | 公開日 | 2019-02-06 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Getting the Most Out of Your Crystals: Data Collection at the New High-Flux, Microfocus MX Beamlines at NSLS-II. Molecules, 24, 2019
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6O9B
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![BU of 6o9b by Molmil](/molmil-images/mine/6o9b) | |
6O9C
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![BU of 6o9c by Molmil](/molmil-images/mine/6o9c) | |
6ALA
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![BU of 6ala by Molmil](/molmil-images/mine/6ala) | Crystal structure of H108A peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with citrate | 分子名称: | CITRATE ANION, COPPER (II) ION, GLYCEROL, ... | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | 登録日 | 2017-08-07 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase. Commun Biol, 1, 2018
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4DWG
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![BU of 4dwg by Molmil](/molmil-images/mine/4dwg) | Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-heptylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, Farnesyl pyrophosphate synthase, ... | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S.B. | 登録日 | 2012-02-24 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
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4DZW
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![BU of 4dzw by Molmil](/molmil-images/mine/4dzw) | Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ | 分子名称: | 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... | 著者 | Aripirala, S, Amzel, L.M, Gabelli, S.B. | 登録日 | 2012-03-01 | 公開日 | 2013-01-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
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7JUL
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![BU of 7jul by Molmil](/molmil-images/mine/7jul) | Crystal structure of non phosphorylated PTEN (n-crPTEN-13sp-T1, SDTTDSDPENEG) | 分子名称: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | 著者 | Dempsey, D, Phan, K, Cole, P, Gabelli, S.B. | 登録日 | 2020-08-20 | 公開日 | 2021-08-11 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.53 Å) | 主引用文献 | The structural basis of PTEN regulation by multi-site phosphorylation. Nat.Struct.Mol.Biol., 28, 2021
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5WJA
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![BU of 5wja by Molmil](/molmil-images/mine/5wja) | Crystal structure of H107A peptidylglycine alpha-hydroxylating monooxygenase (PHM) in complex with citrate | 分子名称: | CITRATE ANION, COPPER (II) ION, GLYCEROL, ... | 著者 | Maheshwari, S, Rudzka, K, Gabelli, S.B, Amzel, L.M. | 登録日 | 2017-07-21 | 公開日 | 2018-07-18 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Effects of copper occupancy on the conformational landscape of peptidylglycine alpha-hydroxylating monooxygenase. Commun Biol, 1, 2018
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