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8STL

Crystal Structure of Nanobody PIK3_Nb16 against wild-type PI3Kalpha

Summary for 8STL
Entry DOI10.2210/pdb8stl/pdb
DescriptorNanobody PIK3_Nb16, SULFATE ION (3 entities in total)
Functional Keywordsnanobody, pi3k, vhh, antibody, chaperone, immune system
Biological sourceLama glama
Total number of polymer chains4
Total formula weight63205.73
Authors
Nwafor, J.N.,Srinivasan, L.,Chen, Z.,Gabelli, S.B.,Iheanacho, A.,Alzogaray, V.,Klinke, S. (deposition date: 2023-05-10, release date: 2024-05-22)
Primary citationNwafor, J.N.,Srinivasan, L.,Chen, Z.,Gabelli, S.B.
Development of isoform specific nanobodies for Class I PI3Ks
To be published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

221051

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