2BOX
 
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium. | | 分子名称: | CACODYLATE ION, CHLORIDE ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, ... | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-14 | | 公開日 | 2006-10-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
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4CUF
 | | Human Notch1 EGF domains 11-13 mutant T466S | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-03-18 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2BO2
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with calcium. | | 分子名称: | CACODYLATE ION, CALCIUM ION, EGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-07 | | 公開日 | 2006-08-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
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2BOU
 | | EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with barium. | | 分子名称: | BARIUM ION, CACODYLATE ION, CALCIUM ION, ... | | 著者 | Abbott, R.J.M, Spendlove, I, Roversi, P, Teriete, P, Knott, V, Handford, P.A, McDonnell, J.M, Lea, S.M. | | 登録日 | 2005-04-14 | | 公開日 | 2006-10-18 | | 最終更新日 | 2017-01-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282, 2007
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4D0F
 | | Human Notch1 EGF domains 11-13 mutant T466A | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | | 登録日 | 2014-04-25 | | 公開日 | 2014-05-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2JMG
 | | Solution structure of V7R mutant of HIV-1 myristoylated matrix protein | | 分子名称: | Gag polyprotein, MYRISTIC ACID | | 著者 | Saad, J.S, Loeliger, E, Luncsford, P, Liriano, M, Tai, J, Kim, A, Miller, J, Joshi, A, Freed, E.O, Summers, M.F. | | 登録日 | 2006-11-11 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-12-20 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Point mutations in the HIV-1 matrix protein turn off the myristyl switch.
J.Mol.Biol., 366, 2007
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1IXA
 | | THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A | | 分子名称: | EGF-LIKE MODULE OF HUMAN FACTOR IX | | 著者 | Baron, M, Norman, D.G, Harvey, T.S, Hanford, P.A, Mayhew, M, Tse, A.G.D, Brownlee, G.G, Campbell, I.D.C. | | 登録日 | 1991-11-14 | | 公開日 | 1993-10-31 | | 最終更新日 | 2022-02-23 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha.
Protein Sci., 1, 1992
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2M74
 | | 1H, 13C and 15N assignments of the four N-terminal domains of human fibrillin-1 | | 分子名称: | Fibrillin-1 | | 著者 | Yadin, D.A, Robertson, I.B, Jensen, S.A, Handford, P.A, Redfield, C. | | 登録日 | 2013-04-17 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly.
Structure, 21, 2013
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2VJ2
 | | Human Jagged-1, domains DSL and EGFs1-3 | | 分子名称: | D-MALATE, JAGGED-1 | | 著者 | Johnson, S, Cordle, J, Tay, J.Z, Roversi, P, Handford, P.A, Lea, S.M. | | 登録日 | 2007-12-06 | | 公開日 | 2008-07-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | A Conserved Face of the Jagged/Serrate Dsl Domain is Involved in Notch Trans-Activation and Cis-Inhibition.
Nat.Struct.Mol.Biol., 15, 2008
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4CC1
 | | Notch ligand, Jagged-1, contains an N-terminal C2 domain | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | | 登録日 | 2013-10-17 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
Cell Rep., 5, 2013
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1HG7
 | | High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus | | 分子名称: | HPLC-12 TYPE III ANTIFREEZE PROTEIN, SULFATE ION | | 著者 | Antson, A.A, Smith, D.J, Roper, D.I, Lewis, S, Caves, L.S.D, Verma, C.S, Buckley, S.L, Lillford, P.J, Hubbard, R.E. | | 登録日 | 2000-12-13 | | 公開日 | 2001-01-31 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Understanding the Mechanism of Ice Binding by Type III Antifreeze Protein
J.Mol.Biol., 305, 2001
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1HJ7
 | | NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures | | 分子名称: | CALCIUM ION, LDL RECEPTOR | | 著者 | Saha, S, Handford, P.A, Campbell, I.D, Downing, A.K. | | 登録日 | 2001-01-09 | | 公開日 | 2001-07-11 | | 最終更新日 | 2018-02-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Ldl Receptor Egf-Ab Pair: A Paradigm for the Assembly of Tandem Calcium Binding Egf Domains
Structure, 9, 2001
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3N5N
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4CBZ
 | | Notch ligand, Jagged-1, contains an N-terminal C2 domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN JAGGED-1, alpha-L-fucopyranose | | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | | 登録日 | 2013-10-17 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
Cell Rep., 5, 2013
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1TOZ
 | | NMR structure of the human NOTCH-1 ligand binding region | | 分子名称: | Neurogenic locus notch homolog protein 1 | | 著者 | Hambleton, S, Valeyev, N.Y, Muranyi, A, Knott, V, Werner, J.M, Mcmichael, A.J, Handford, P.A, Downing, A.K. | | 登録日 | 2004-06-15 | | 公開日 | 2004-10-12 | | 最終更新日 | 2021-11-10 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and functional properties of the human notch-1 ligand binding region
STRUCTURE, 12, 2004
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1KSQ
 | | NMR Study of the Third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1 | | 分子名称: | LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1 | | 著者 | Lack, J, O'leary, J.M, Knott, V, Yuan, X, Rifkin, D.B, Handford, P.A, Downing, A.K. | | 登録日 | 2002-01-14 | | 公開日 | 2003-08-26 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly
of the Large Latent Complex that Sequesters Latent TGF-beta.
J.Mol.Biol., 334, 2003
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1UZJ
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | | 分子名称: | CALCIUM ION, FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-12 | | 公開日 | 2004-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
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1UPH
 | | HIV-1 Myristoylated Matrix | | 分子名称: | GAG POLYPROTEIN | | 著者 | Tang, C, Loeliger, E, Luncsford, P, Kinde, I, Beckett, D, Summers, M.F. | | 登録日 | 2003-10-01 | | 公開日 | 2004-01-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Entropic Switch Regulates Myristate Exposure in the HIV-1 Matrix Protein
Proc.Natl.Acad.Sci.USA, 101, 2004
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4CC0
 | | Notch ligand, Jagged-1, contains an N-terminal C2 domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN JAGGED-1, ... | | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | | 登録日 | 2013-10-17 | | 公開日 | 2013-11-27 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands
Cell Rep., 5, 2013
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2APS
 | | CU/ZN SUPEROXIDE DISMUTASE FROM ACTINOBACILLUS PLEUROPNEUMONIAE | | 分子名称: | COPPER (II) ION, PROTEIN (CU,ZN SUPEROXIDE DISMUTASE), ZINC ION | | 著者 | Forest, K.T, Langford, P.R, Kroll, J.S, Getzoff, E.D. | | 登録日 | 1999-02-11 | | 公開日 | 1999-02-25 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface.
J.Mol.Biol., 296, 2000
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1APJ
 | | NMR STUDY OF THE TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN-LIKE DOMAIN (TB MODULE/8-CYS DOMAIN), NMR, 21 STRUCTURES | | 分子名称: | FIBRILLIN | | 著者 | Yuan, X, Downing, A.K, Knott, V, Handford, P.A. | | 登録日 | 1997-07-22 | | 公開日 | 1998-01-28 | | 最終更新日 | 2021-11-03 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils.
EMBO J., 16, 1997
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1UZK
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only | | 分子名称: | CALCIUM ION, FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-13 | | 公開日 | 2006-05-24 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
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1UZP
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only. | | 分子名称: | FIBRILLIN-1, SAMARIUM (III) ION | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-15 | | 公開日 | 2004-04-08 | | 最終更新日 | 2019-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
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1UZQ
 | | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only. | | 分子名称: | FIBRILLIN-1 | | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | | 登録日 | 2004-03-15 | | 公開日 | 2004-04-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization
Structure, 12, 2004
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2W86
 | | Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form | | 分子名称: | CALCIUM ION, FIBRILLIN-1, IODIDE ION | | 著者 | Jensen, S.A, Iqbal, S, Lowe, E.D, Redfield, C, Handford, P.A. | | 登録日 | 2009-01-09 | | 公開日 | 2009-05-26 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17, 2009
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