2M74
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![BU of 2m74 by Molmil](/molmil-images/mine/2m74) | 1H, 13C and 15N assignments of the four N-terminal domains of human fibrillin-1 | 分子名称: | Fibrillin-1 | 著者 | Yadin, D.A, Robertson, I.B, Jensen, S.A, Handford, P.A, Redfield, C. | 登録日 | 2013-04-17 | 公開日 | 2013-09-25 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Fibrillin-1 N-Terminal Domains Suggests that Heparan Sulfate Regulates the Early Stages of Microfibril Assembly. Structure, 21, 2013
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5AM6
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![BU of 5am6 by Molmil](/molmil-images/mine/5am6) | Native FGFR1 with an inhibitor | 分子名称: | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one, CHLORIDE ION, FIBROBLAST GROWTH FACTOR RECEPTOR 1 | 著者 | Bunney, T.D, Wan, S, Thiyagarajan, N, Sutto, L, Williams, S.V, Ashford, P, Koss, H, Knowles, M.A, Gervasio, F.L, Coveney, P.V, Katan, M. | 登録日 | 2015-03-10 | 公開日 | 2015-03-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine, 2, 2015
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4CUF
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![BU of 4cuf by Molmil](/molmil-images/mine/4cuf) | Human Notch1 EGF domains 11-13 mutant T466S | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-03-18 | 公開日 | 2014-05-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4D0E
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![BU of 4d0e by Molmil](/molmil-images/mine/4d0e) | Human Notch1 EGF domains 11-13 mutant GlcNAc-fucose disaccharide modified at T466 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-04-25 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CUD
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![BU of 4cud by Molmil](/molmil-images/mine/4cud) | Human Notch1 EGF domains 11-13 mutant fucosylated at T466 | 分子名称: | CALCIUM ION, NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1, alpha-L-fucopyranose | 著者 | Taylor, P, Takeuchi, H, Sheppard, D, Chillakuri, C, Lea, S.M, Haltiwanger, R.S, Handford, P.A. | 登録日 | 2014-03-18 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Fringe-Mediated Extension of O-Linked Fucose in the Ligand-Binding Region of Notch1 Increases Binding to Mammalian Notch Ligands. Proc.Natl.Acad.Sci.USA, 111, 2014
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4CC1
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![BU of 4cc1 by Molmil](/molmil-images/mine/4cc1) | Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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1EQW
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![BU of 1eqw by Molmil](/molmil-images/mine/1eqw) | CRYSTAL STRUCTURE OF SALMONELLA TYPHIMURIUM CU,ZN SUPEROXIDE DISMUTASE | 分子名称: | COPPER (II) ION, CU,ZN SUPEROXIDE DISMUTASE, ZINC ION | 著者 | Pesce, A, Battistoni, A, Stroppolo, M.E, Polizio, F, Nardini, M, Kroll, J.S, Langford, P.R, O'Neill, P, Sette, M, Desideri, A, Bolognesi, M. | 登録日 | 2000-04-06 | 公開日 | 2000-09-08 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Functional and crystallographic characterization of Salmonella typhimurium Cu,Zn superoxide dismutase coded by the sodCI virulence gene. J.Mol.Biol., 302, 2000
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1TOZ
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![BU of 1toz by Molmil](/molmil-images/mine/1toz) | NMR structure of the human NOTCH-1 ligand binding region | 分子名称: | Neurogenic locus notch homolog protein 1 | 著者 | Hambleton, S, Valeyev, N.Y, Muranyi, A, Knott, V, Werner, J.M, Mcmichael, A.J, Handford, P.A, Downing, A.K. | 登録日 | 2004-06-15 | 公開日 | 2004-10-12 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional properties of the human notch-1 ligand binding region STRUCTURE, 12, 2004
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1KSQ
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![BU of 1ksq by Molmil](/molmil-images/mine/1ksq) | NMR Study of the Third TB Domain from Latent Transforming Growth Factor-beta Binding Protein-1 | 分子名称: | LATENT TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN 1 | 著者 | Lack, J, O'leary, J.M, Knott, V, Yuan, X, Rifkin, D.B, Handford, P.A, Downing, A.K. | 登録日 | 2002-01-14 | 公開日 | 2003-08-26 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Third TB Domain from LTBP1 Provides Insight into Assembly
of the Large Latent Complex that Sequesters Latent TGF-beta. J.Mol.Biol., 334, 2003
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1EMN
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![BU of 1emn by Molmil](/molmil-images/mine/1emn) | NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, MINIMIZED AVERAGE STRUCTURE | 分子名称: | CALCIUM ION, FIBRILLIN | 著者 | Downing, A.K, Campbell, I.D, Handford, P.A. | 登録日 | 1996-08-05 | 公開日 | 1996-12-23 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders. Cell(Cambridge,Mass.), 85, 1996
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1EMO
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![BU of 1emo by Molmil](/molmil-images/mine/1emo) | NMR STUDY OF A PAIR OF FIBRILLIN CA2+ BINDING EPIDERMAL GROWTH FACTOR-LIKE DOMAINS, 22 STRUCTURES | 分子名称: | CALCIUM ION, FIBRILLIN | 著者 | Downing, A.K, Campbell, I.D, Handford, P.A. | 登録日 | 1996-08-05 | 公開日 | 1996-12-23 | 最終更新日 | 2021-10-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of a pair of calcium-binding epidermal growth factor-like domains: implications for the Marfan syndrome and other genetic disorders. Cell(Cambridge,Mass.), 85, 1996
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1APJ
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![BU of 1apj by Molmil](/molmil-images/mine/1apj) | NMR STUDY OF THE TRANSFORMING GROWTH FACTOR BETA BINDING PROTEIN-LIKE DOMAIN (TB MODULE/8-CYS DOMAIN), NMR, 21 STRUCTURES | 分子名称: | FIBRILLIN | 著者 | Yuan, X, Downing, A.K, Knott, V, Handford, P.A. | 登録日 | 1997-07-22 | 公開日 | 1998-01-28 | 最終更新日 | 2021-11-03 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the transforming growth factor beta-binding protein-like module, a domain associated with matrix fibrils. EMBO J., 16, 1997
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1UPH
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![BU of 1uph by Molmil](/molmil-images/mine/1uph) | HIV-1 Myristoylated Matrix | 分子名称: | GAG POLYPROTEIN | 著者 | Tang, C, Loeliger, E, Luncsford, P, Kinde, I, Beckett, D, Summers, M.F. | 登録日 | 2003-10-01 | 公開日 | 2004-01-08 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Entropic Switch Regulates Myristate Exposure in the HIV-1 Matrix Protein Proc.Natl.Acad.Sci.USA, 101, 2004
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1UZJ
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![BU of 1uzj by Molmil](/molmil-images/mine/1uzj) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, holo form. | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-12 | 公開日 | 2004-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1EDM
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![BU of 1edm by Molmil](/molmil-images/mine/1edm) | EPIDERMAL GROWTH FACTOR-LIKE DOMAIN FROM HUMAN FACTOR IX | 分子名称: | CALCIUM ION, FACTOR IX | 著者 | Rao, Z, Handford, P, Mayhew, M, Knott, V, Brownlee, G.G, Stuart, D. | 登録日 | 1996-03-21 | 公開日 | 1996-10-14 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structure of a Ca(2+)-binding epidermal growth factor-like domain: its role in protein-protein interactions. Cell(Cambridge,Mass.), 82, 1995
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4CBZ
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![BU of 4cbz by Molmil](/molmil-images/mine/4cbz) | Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN JAGGED-1, alpha-L-fucopyranose | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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4CC0
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![BU of 4cc0 by Molmil](/molmil-images/mine/4cc0) | Notch ligand, Jagged-1, contains an N-terminal C2 domain | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PROTEIN JAGGED-1, ... | 著者 | Chilakuri, C.R, Sheppard, D, Ilagan, M.X.G, Holt, L.R, Abbott, F, Liang, S, Kopan, R, Handford, P.A, Lea, S.M. | 登録日 | 2013-10-17 | 公開日 | 2013-11-27 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Structural Analysis Uncovers Lipid-Binding Properties of Notch Ligands Cell Rep., 5, 2013
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1IXA
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![BU of 1ixa by Molmil](/molmil-images/mine/1ixa) | THE THREE-DIMENSIONAL STRUCTURE OF THE FIRST EGF-LIKE MODULE OF HUMAN FACTOR IX: COMPARISON WITH EGF AND TGF-A | 分子名称: | EGF-LIKE MODULE OF HUMAN FACTOR IX | 著者 | Baron, M, Norman, D.G, Harvey, T.S, Hanford, P.A, Mayhew, M, Tse, A.G.D, Brownlee, G.G, Campbell, I.D.C. | 登録日 | 1991-11-14 | 公開日 | 1993-10-31 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | The three-dimensional structure of the first EGF-like module of human factor IX: comparison with EGF and TGF-alpha. Protein Sci., 1, 1992
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2APS
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![BU of 2aps by Molmil](/molmil-images/mine/2aps) | CU/ZN SUPEROXIDE DISMUTASE FROM ACTINOBACILLUS PLEUROPNEUMONIAE | 分子名称: | COPPER (II) ION, PROTEIN (CU,ZN SUPEROXIDE DISMUTASE), ZINC ION | 著者 | Forest, K.T, Langford, P.R, Kroll, J.S, Getzoff, E.D. | 登録日 | 1999-02-11 | 公開日 | 1999-02-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Cu,Zn superoxide dismutase structure from a microbial pathogen establishes a class with a conserved dimer interface. J.Mol.Biol., 296, 2000
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1UZP
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![BU of 1uzp by Molmil](/molmil-images/mine/1uzp) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Sm bound form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1, SAMARIUM (III) ION | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1UZK
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![BU of 1uzk by Molmil](/molmil-images/mine/1uzk) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, Ca bound to cbEGF23 domain only | 分子名称: | CALCIUM ION, FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-13 | 公開日 | 2006-05-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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1UZQ
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![BU of 1uzq by Molmil](/molmil-images/mine/1uzq) | Integrin binding cbEGF22-TB4-cbEGF33 fragment of human fibrillin-1, apo form cbEGF23 domain only. | 分子名称: | FIBRILLIN-1 | 著者 | Lee, S.S.J, Knott, V, Harlos, K, Handford, P.A, Stuart, D.I. | 登録日 | 2004-03-15 | 公開日 | 2004-04-08 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of the Integrin Binding Fragment from Fibrillin-1 Gives New Insights Into Microfibril Organization Structure, 12, 2004
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2W86
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![BU of 2w86 by Molmil](/molmil-images/mine/2w86) | Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form | 分子名称: | CALCIUM ION, FIBRILLIN-1, IODIDE ION | 著者 | Jensen, S.A, Iqbal, S, Lowe, E.D, Redfield, C, Handford, P.A. | 登録日 | 2009-01-09 | 公開日 | 2009-05-26 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins. Structure, 17, 2009
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1HG7
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![BU of 1hg7 by Molmil](/molmil-images/mine/1hg7) | High resolution structure of HPLC-12 type III antifreeze protein from Ocean Pout Macrozoarces americanus | 分子名称: | HPLC-12 TYPE III ANTIFREEZE PROTEIN, SULFATE ION | 著者 | Antson, A.A, Smith, D.J, Roper, D.I, Lewis, S, Caves, L.S.D, Verma, C.S, Buckley, S.L, Lillford, P.J, Hubbard, R.E. | 登録日 | 2000-12-13 | 公開日 | 2001-01-31 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Understanding the Mechanism of Ice Binding by Type III Antifreeze Protein J.Mol.Biol., 305, 2001
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1HJ7
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![BU of 1hj7 by Molmil](/molmil-images/mine/1hj7) | NMR study of a pair of LDL receptor Ca2+ binding epidermal growth factor-like domains, 20 structures | 分子名称: | CALCIUM ION, LDL RECEPTOR | 著者 | Saha, S, Handford, P.A, Campbell, I.D, Downing, A.K. | 登録日 | 2001-01-09 | 公開日 | 2001-07-11 | 最終更新日 | 2018-02-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Ldl Receptor Egf-Ab Pair: A Paradigm for the Assembly of Tandem Calcium Binding Egf Domains Structure, 9, 2001
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