2BOX

EGF Domains 1,2,5 of human EMR2, a 7-TM immune system molecule, in complex with strontium.

Summary for 2BOX

Related2BO2 2BOU
DescriptorEGF-LIKE MODULE CONTAINING MUCIN-LIKE HORMONE RECEPTOR-LIKE 2 PRECURSOR, STRONTIUM ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywordscd97, cd55, 7tm, calcium-binding, cell adhesion, egf-like domain, g-protein coupled receptor, immune system
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCell membrane; Multi-pass membrane protein Q9UHX3
Total number of polymer chains1
Total molecular weight15940.78
Authors
Abbott, R.J.M.,Spendlove, I.,Roversi, P.,Teriete, P.,Knott, V.,Handford, P.A.,McDonnell, J.M.,Lea, S.M. (deposition date: 2005-04-14, release date: 2006-10-18, Last modification date: 2011-07-13)
Primary citation
Abbott, R.J.M.,Spendlove, I.,Roversi, P.,Fitzgibbon, H.,Knott, V.,Teriete, P.,Mcdonnell, J.M.,Handford, P.A.,Lea, S.M.
Structural and Functional Characterization of a Novel T Cell Receptor Co-Regulatory Protein Complex, Cd97-Cd55.
J.Biol.Chem., 282:22023-, 2007
PubMed: 17449467 (PDB entries with the same primary citation)
DOI: 10.1074/JBC.M702588200
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2501506.7%8.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2box
no rotation
Molmil generated image of 2box
rotated about x axis by 90°
Molmil generated image of 2box
rotated about y axis by 90°