2W86

Crystal structure of fibrillin-1 domains cbEGF9hyb2cbEGF10, calcium saturated form

Summary for 2W86

Related1UZK 1UZJ 1UZP 1APJ 1UZQ 1LMJ
DescriptorFIBRILLIN-1, CALCIUM ION, IODIDE ION, ... (4 entities in total)
Functional Keywordsfibrillin, phosphoprotein, egf-like domain, disease mutation, craniosynostosis, extracellular matrix, fibrillin calcium cbegf hybrid, calcium, secreted, polymorphism, glycoprotein
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted, extracellular space, extracellular matrix P35555
Total number of polymer chains1
Total molecular weight15988.58
Authors
Jensen, S.A.,Iqbal, S.,Lowe, E.D.,Redfield, C.,Handford, P.A. (deposition date: 2009-01-09, release date: 2009-05-26, Last modification date: 2011-07-13)
Primary citation
Jensen, S.A.,Iqbal, S.,Lowe, E.D.,Redfield, C.,Handford, P.A.
Structure and Interdomain Interactions of a Hybrid Domain: A Disulphide-Rich Module of the Fibrillin/Ltbp Superfamily of Matrix Proteins.
Structure, 17:759-, 2009
PubMed: 19446531 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2009.03.014
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.8 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers70.7%0.8%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2w86
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Molmil generated image of 2w86
rotated about x axis by 90°
Molmil generated image of 2w86
rotated about y axis by 90°
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