5HW9
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P21 | 分子名称: | Green fluorescent protein | 著者 | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | 登録日 | 2016-01-29 | 公開日 | 2017-02-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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5VOS
| VGSNKGAIIGL from Amyloid Beta determined by MicroED | 分子名称: | Amyloid beta A4 protein | 著者 | Rodriguez, J.A, Sawaya, M.R, Cascio, D, Eisenberg, D.S, Griner, S.L, Gonen, T. | 登録日 | 2017-05-03 | 公開日 | 2018-01-03 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.42 Å) | 主引用文献 | Common fibrillar spines of amyloid-beta and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors. J. Biol. Chem., 293, 2018
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5HBD
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group C2 | 分子名称: | Green fluorescent protein | 著者 | Sawaya, M.R, Hochschild, A, Heller, D.M, McPartland, L, Eisenberg, D.S. | 登録日 | 2015-12-31 | 公開日 | 2017-01-04 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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6CU8
| Alpha Synuclein fibril formed by full length protein - Twister Polymorph | 分子名称: | Alpha-synuclein | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | 登録日 | 2018-03-23 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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3AL1
| DESIGNED PEPTIDE ALPHA-1, RACEMIC P1BAR FORM | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ETHANOLAMINE, PROTEIN (D, ... | 著者 | Patterson, W.R, Anderson, D.H, Degrado, W.F, Cascio, D, Eisenberg, D. | 登録日 | 1998-10-26 | 公開日 | 1998-11-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (0.75 Å) | 主引用文献 | Centrosymmetric bilayers in the 0.75 A resolution structure of a designed alpha-helical peptide, D,L-Alpha-1. Protein Sci., 8, 1999
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5WIA
| Crystal structure of the segment, GNNSYS, from the low complexity domain of TDP-43, residues 370-375 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-18 | 公開日 | 2018-04-25 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.002 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WKD
| Crystal structure of the segment, GNNQGSN, from the low complexity domain of TDP-43, residues 300-306 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Trinh, H, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-07-25 | 公開日 | 2018-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5WHP
| Crystal structure of the segment, NFGTFS, from the A315T familial variant of the low complexity domain of TDP-43, residues 312-317 | 分子名称: | Segment of TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-17 | 公開日 | 2018-05-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5W52
| MicroED structure of the segment, DLIIKGISVHI, from the RRM2 of TDP-43, residues 247-257 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-06-13 | 公開日 | 2018-02-21 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | 主引用文献 | Atomic-level evidence for packing and positional amyloid polymorphism by segment from TDP-43 RRM2. Nat. Struct. Mol. Biol., 25, 2018
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5WKB
| MicroED structure of the segment, NFGEFS, from the A315E familial variant of the low complexity domain of TDP-43, residues 312-317 | 分子名称: | TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Cascio, D, Eisenberg, D.S. | 登録日 | 2017-07-24 | 公開日 | 2018-05-23 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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5HGE
| Filamentous Assembly of Green Fluorescent Protein Supported by a C-terminal fusion of 18-residues, viewed in space group P212121 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Green fluorescent protein | 著者 | Sawaya, M.R, Heller, D.M, McPartland, L, Hochschild, A, Eisenberg, D.S. | 登録日 | 2016-01-08 | 公開日 | 2017-01-11 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.863 Å) | 主引用文献 | Green Fluorescent Protein Fusion that Self Assembles as Polar Filaments to be published
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8DDH
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7N8R
| FGTGFG segment from the Nucleoporin p54, residues 63-68 | 分子名称: | FGTGFG segment from the Nucleoporin p54, residues 63-68, trifluoroacetic acid | 著者 | Hughes, M.P, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2021-06-15 | 公開日 | 2022-02-16 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Extended beta-Strands Contribute to Reversible Amyloid Formation. Acs Nano, 16, 2022
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7K3C
| SGMGGIT segment 58-64 from Keratin-8 | 分子名称: | ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL | 著者 | Murray, K.A, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2020-09-11 | 公開日 | 2021-11-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29, 2022
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5WHN
| Crystal structure of the segment, NFGAFS, from the low complexity domain of TDP-43, residues 312-317 | 分子名称: | Segment of TAR DNA-binding protein 43 | 著者 | Guenther, E.L, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2017-07-17 | 公開日 | 2018-04-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6N3A
| SegA-long, conformation of TDP-43 low complexity domain segment A long | 分子名称: | TAR DNA-binding protein 43, segA long small | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-11-14 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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3DMK
| Crystal structure of Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, N-terminal eight Ig domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule (DSCAM) isoform 1.30.30, ... | 著者 | Sawaya, M.R, Wojtowicz, W.M, Eisenberg, D, Zipursky, S.L. | 登録日 | 2008-07-01 | 公開日 | 2008-10-07 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (4.19 Å) | 主引用文献 | A double S shape provides the structural basis for the extraordinary binding specificity of Dscam isoforms. Cell(Cambridge,Mass.), 134, 2008
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6N37
| SegA-sym, conformation of TDP-43 low complexity domain segment A sym | 分子名称: | TAR DNA-binding protein 43 | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-11-14 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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6N3C
| SegB, conformation of TDP-43 low complexity domain segment A | 分子名称: | TAR DNA-binding protein 43 | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-11-14 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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6N3B
| SegA-asym, conformation of TDP-43 low complexity domain segment A asym | 分子名称: | TAR DNA-binding protein 43 | 著者 | Cao, Q, Boyer, D.R, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-11-14 | 公開日 | 2019-06-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26, 2019
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2Y3K
| Structure of segment MVGGVVIA from the amyloid-beta peptide (Ab, residues 35-42), alternate polymorph 1 | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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2Y3J
| Structure of segment AIIGLM from the amyloid-beta peptide (Ab, residues 30-35) | 分子名称: | AMYLOID BETA A4 PROTEIN | 著者 | Colletier, J.P, Laganowsky, A, Sawaya, M.R, Eisenberg, D. | 登録日 | 2010-12-21 | 公開日 | 2011-11-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Molecular Basis for Amyloid-{Beta} Polymorphism. Proc.Natl.Acad.Sci.USA, 108, 2011
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6CB9
| Segment AALQSS from the low complexity domain of TDP-43, residues 328-333 | 分子名称: | AALQSS | 著者 | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-02-02 | 公開日 | 2018-04-18 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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6CEW
| Segment AMMAAA from the low complexity domain of TDP-43, residues 321-326 | 分子名称: | AMMAAA | 著者 | Guenther, E.L, Cao, Q, Lu, J, Sawaya, M.R, Eisenberg, D.S. | 登録日 | 2018-02-12 | 公開日 | 2018-04-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation. Nat. Struct. Mol. Biol., 25, 2018
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4ZJM
| Crystal Structure of Mycobacterium tuberculosis LpqH (Rv3763) | 分子名称: | CHLORIDE ION, GLYCEROL, Lipoprotein LpqH, ... | 著者 | Arbing, M.A, Chan, S, Kuo, E, Harris, L.R, Zhou, T.T, Eisenberg, D, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2015-04-29 | 公開日 | 2015-05-13 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.851 Å) | 主引用文献 | Crystal Structure of Mycobacterium tuberculosis LpqH (Rv3763) To Be Published
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