6N37

SegA-sym, conformation of TDP-43 low complexity domain segment A sym

Summary for 6N37

Entry DOI	10.2210/pdb6n37/pdb
EMDB information	9339
Descriptor	TAR DNA-binding protein 43 (1 entity in total)
Functional Keywords	amyloid, tdp43, als, ftld-tdp, protein fibril
Biological source	Homo sapiens (Human)
Total number of polymer chains	10
Total formula weight	52077.97
Authors	Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-11-14, release date: 2019-06-26, Last modification date: 2024-03-20)
Primary citation	Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Ge, P.,Eisenberg, D.S. Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26:619-627, 2019 Cited by PubMed: 31235914 DOI: 10.1038/s41594-019-0248-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation