6N3A

SegA-long, conformation of TDP-43 low complexity domain segment A long

Summary for 6N3A

Entry DOI	10.2210/pdb6n3a/pdb
Related	6N37 6N3B 6N3C
EMDB information	0334 9339 9349 9350
Descriptor	TAR DNA-binding protein 43, segA long small (2 entities in total)
Functional Keywords	amyloid, tdp43, als, ftld-tdp, dna binding protein, protein fibril
Biological source	Homo sapiens (Human) More
Total number of polymer chains	20
Total formula weight	62709.40
Authors	Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2018-11-14, release date: 2019-06-26, Last modification date: 2024-03-20)
Primary citation	Cao, Q.,Boyer, D.R.,Sawaya, M.R.,Ge, P.,Eisenberg, D.S. Cryo-EM structures of four polymorphic TDP-43 amyloid cores. Nat.Struct.Mol.Biol., 26:619-627, 2019 Cited by PubMed: 31235914 DOI: 10.1038/s41594-019-0248-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation