7K3C

SGMGGIT segment 58-64 from Keratin-8

Summary for 7K3C

Entry DOI	10.2210/pdb7k3c/pdb
Descriptor	SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, ETHANOL, TRIETHYLENE GLYCOL, ... (4 entities in total)
Functional Keywords	amyloid filament, low complexity sequence, protein fibril
Biological source	Homo sapiens
Total number of polymer chains	2
Total formula weight	1485.72
Authors	Murray, K.A.,Sawaya, M.R.,Eisenberg, D.S. (deposition date: 2020-09-11, release date: 2021-11-10, Last modification date: 2022-07-06)
Primary citation	Murray, K.A.,Hughes, M.P.,Hu, C.J.,Sawaya, M.R.,Salwinski, L.,Pan, H.,French, S.W.,Seidler, P.M.,Eisenberg, D.S. Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies. Nat.Struct.Mol.Biol., 29:529-536, 2022 Cited by PubMed: 35637421 DOI: 10.1038/s41594-022-00774-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.1 Å)

Structure validation