7MPB
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![BU of 7mpb by Molmil](/molmil-images/mine/7mpb) | SARS Coronavirus-2 Main Protease 3CL-pro binding Ascorbate | Descriptor: | 3C-like proteinase, ASCORBIC ACID, TRIFLUOROETHANOL | Authors: | Pandey, S, Malla, T.N, Stojkovic, E.A, Schmidt, M. | Deposit date: | 2021-05-04 | Release date: | 2021-05-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Vitamin C inhibits SARS coronavirus-2 main protease essential for viral replication Biorxiv, 2021
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7M2X
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![BU of 7m2x by Molmil](/molmil-images/mine/7m2x) | Open conformation of the Yeast wild-type gamma-TuRC | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Spindle pole body component 110, Spindle pole body component SPC97, ... | Authors: | Brilot, A.F, Lyon, A.S, Zelter, A, Viswanath, S, Maxwell, A, MacCoss, M.J, Muller, E.G, Sali, A, Davis, T.N, Agard, D.A. | Deposit date: | 2021-03-17 | Release date: | 2021-05-12 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | CM1-driven assembly and activation of yeast gamma-tubulin small complex underlies microtubule nucleation. Elife, 10, 2021
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2PW2
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![BU of 2pw2 by Molmil](/molmil-images/mine/2pw2) | Crystal structure of the HIV-1 Cross Neutralizing Monoclonal Antibody 2F5 in complex with gp41 Peptide ELDKWKSL | Descriptor: | 2F5 Fab' heavy chain, 2F5 Fab' light chain, peptide epitope | Authors: | Bryson, S, Julien, J.-P, Hynes, R.C, Pai, E.F. | Deposit date: | 2007-05-10 | Release date: | 2007-05-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Crystallographic definition of the epitope promiscuity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5: vaccine design implications. J.Virol., 83, 2009
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4NDR
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![BU of 4ndr by Molmil](/molmil-images/mine/4ndr) | Crystal structure Molybdenum Storage Protein with fully Mo-loaded cavity | Descriptor: | (mu3-oxo)-tris(mu2-oxo)-nonakisoxo-trimolybdenum (VI), ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Poppe, J, Warkentin, E, Demmer, U, Ermler, U. | Deposit date: | 2013-10-27 | Release date: | 2014-08-13 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural diversity of polyoxomolybdate clusters along the three-fold axis of the molybdenum storage protein. J.Inorg.Biochem., 138, 2014
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4NFR
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![BU of 4nfr by Molmil](/molmil-images/mine/4nfr) | |
5W07
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![BU of 5w07 by Molmil](/molmil-images/mine/5w07) | CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333. | Descriptor: | (~{N}~{E})-~{N}-[[2-[[2-ethylsulfonyl-1,1-bis(oxidanyl)-3,4-dihydro-2,3,1$l^{4}-benzodiazaborinin-7-yl]oxy]-5-(trifluoromethyl)phenyl]methylidene]hydroxylamine, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Abendroth, J, Edwards, T.E, Lorimer, D. | Deposit date: | 2017-05-30 | Release date: | 2018-06-13 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA To Be Published
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8RC7
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2Q6E
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![BU of 2q6e by Molmil](/molmil-images/mine/2q6e) | Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn | Descriptor: | BH0493 protein, CHLORIDE ION, SODIUM ION, ... | Authors: | Fedorov, A.A, Fedorov, E.V, Patskovsky, Y, Toro, R, Sauder, J.M, Burley, S.K, Rauschel, F.M, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | Deposit date: | 2007-06-05 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of glucuronate isomerase from Bacillus halodurans complexed with Zn. To be Published
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6DGG
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2PG7
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![BU of 2pg7 by Molmil](/molmil-images/mine/2pg7) | Crystal Structure of Human Microsomal P450 2A6 N297Q/I300V | Descriptor: | Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Sansen, S, Hsu, M.H, Stout, C.D, Johnson, E.F. | Deposit date: | 2007-04-06 | Release date: | 2007-07-24 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural insight into the altered substrate specificity of human cytochrome P450 2A6 mutants. Arch.Biochem.Biophys., 464, 2007
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4NO3
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![BU of 4no3 by Molmil](/molmil-images/mine/4no3) | Crystal structure of AMPD2 phosphopeptide bound to HLA-A2 | Descriptor: | 1,2-ETHANEDIOL, AMP deaminase 2, Beta-2-microglobulin, ... | Authors: | Mohammed, F, Stones, D.H, Willcox, B.E. | Deposit date: | 2013-11-19 | Release date: | 2014-12-24 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.703 Å) | Cite: | The antigenic identity of human class I MHC phosphopeptides is critically dependent upon phosphorylation status. Oncotarget, 8, 2017
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4NP4
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![BU of 4np4 by Molmil](/molmil-images/mine/4np4) | Clostridium difficile toxin B CROP domain in complex with FAB domains of neutralizing antibody bezlotoxumab | Descriptor: | Toxin B, bezlotoxumab heavy chain, bezlotoxumab light chain | Authors: | Orth, P, Xiao, L, Hernandez, L.D, Reichert, P, Sheth, P, Beaumont, M, Murgolo, N, Ermakov, G, DiNunzio, E, Racine, F, Karczewski, J, Secore, S, Ingram, R.N, Mayhood, T, Strickland, C, Therien, A.G. | Deposit date: | 2013-11-20 | Release date: | 2014-05-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Mechanism of Action and Epitopes of Clostridium difficile Toxin B-neutralizing Antibody Bezlotoxumab Revealed by X-ray Crystallography. J.Biol.Chem., 289, 2014
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4NTD
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![BU of 4ntd by Molmil](/molmil-images/mine/4ntd) | Crystal structure of HlmI | Descriptor: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE, ... | Authors: | Scharf, D.H, Groll, M, Habel, A, Heinekamp, T, Hertweck, C, Brakhage, A.A, Huber, E.M. | Deposit date: | 2013-12-02 | Release date: | 2014-03-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products Angew.Chem.Int.Ed.Engl., 53, 2014
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4NTW
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![BU of 4ntw by Molmil](/molmil-images/mine/4ntw) | Structure of acid-sensing ion channel in complex with snake toxin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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2PK8
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![BU of 2pk8 by Molmil](/molmil-images/mine/2pk8) | Crystal structure of an uncharacterized protein PF0899 from Pyrococcus furiosus | Descriptor: | GOLD (I) CYANIDE ION, Uncharacterized protein PF0899 | Authors: | Liu, Z.J, Tempel, W, Chen, L, Shah, A, Lee, D, Clancy-Kelley, L.L, Dillard, B.D, Rose, J.P, Sugar, F.J, Jenny Jr, F.E, Lee, H.S, Izumi, M, Shah, C, Poole III, F.L, Adams, M.W.W, Richardson, J.S, Richardson, D.C, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2007-04-17 | Release date: | 2007-05-22 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structure of the hypothetical protein PF0899 from Pyrococcus furiosus at 1.85 A resolution. Acta Crystallogr.,Sect.F, 63, 2007
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6TTL
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![BU of 6ttl by Molmil](/molmil-images/mine/6ttl) | crystal structure of [FeFe]-hydrogenase CbA5H (partial) from Clostridium beijerinckii in Hinact state | Descriptor: | IRON/SULFUR CLUSTER, [FeFe]-hydrogenase, dicarbonyl[bis(cyanide-kappaC)]-mu-(iminodimethanethiolatato-1kappaS:2kappaS)-mu-(oxomethylidene)diiron(2+) | Authors: | Duan, J, Rutz, A, Hofmann, E, Happe, T. | Deposit date: | 2019-12-28 | Release date: | 2020-12-09 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A safety cap protects hydrogenase from oxygen attack. Nat Commun, 12, 2021
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5VRL
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![BU of 5vrl by Molmil](/molmil-images/mine/5vrl) | CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333. | Descriptor: | (~{N}~{E})-~{N}-[[2-[[2-ethylsulfonyl-1,1-bis(oxidanyl)-3,4-dihydro-2,3,1$l^{4}-benzodiazaborinin-7-yl]oxy]-5-(trifluoromethyl)phenyl]methylidene]hydroxylamine, Enoyl-[acyl-carrier-protein] reductase [NADH] | Authors: | Abendroth, J, Edwards, T.E, Lorimer, D. | Deposit date: | 2017-05-11 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Discovery of a cofactor-independent inhibitor ofMycobacterium tuberculosisInhA. Life Sci Alliance, 1, 2018
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7MOA
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![BU of 7moa by Molmil](/molmil-images/mine/7moa) | Cryo-EM structure of the c-MET II/HGF I complex bound with HGF II in a rigid conformation | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, Hepatocyte growth factor, Hepatocyte growth factor receptor | Authors: | Uchikawa, E, Chen, Z.M, Xiao, G.Y, Zhang, X.W, Bai, X.C. | Deposit date: | 2021-05-01 | Release date: | 2021-06-09 | Last modified: | 2021-07-28 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structural basis of the activation of c-MET receptor. Nat Commun, 12, 2021
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4NTY
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![BU of 4nty by Molmil](/molmil-images/mine/4nty) | Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin | Descriptor: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | Authors: | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | Deposit date: | 2013-12-02 | Release date: | 2014-02-19 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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6TN8
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![BU of 6tn8 by Molmil](/molmil-images/mine/6tn8) | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound BI-9564 | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one, ... | Authors: | Williams, E.P, Chen, Z, Burgess-Brown, N, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A.N. | Deposit date: | 2019-12-06 | Release date: | 2019-12-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structure of the ACVR1 (ALK2) kinase in complex with the compound BI-9564 To Be Published
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4NWQ
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![BU of 4nwq by Molmil](/molmil-images/mine/4nwq) | Computationally Designed Two-Component Self-Assembling Tetrahedral Cage, T33-21, Crystallized in Space Group F4132 | Descriptor: | Putative uncharacterized protein PH0671, SULFATE ION, Uncharacterized protein | Authors: | McNamara, D.E, King, N.P, Bale, J.B, Sheffler, W, Baker, D, Yeates, T.O. | Deposit date: | 2013-12-06 | Release date: | 2014-05-28 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Accurate design of co-assembling multi-component protein nanomaterials. Nature, 510, 2014
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2PP3
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![BU of 2pp3 by Molmil](/molmil-images/mine/2pp3) | Crystal structure of L-talarate/galactarate dehydratase mutant K197A liganded with Mg and L-glucarate | Descriptor: | L-GLUCARIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION | Authors: | Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C. | Deposit date: | 2007-04-27 | Release date: | 2007-08-07 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2. Biochemistry, 46, 2007
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4ZGQ
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![BU of 4zgq by Molmil](/molmil-images/mine/4zgq) | Structure of Cdc123 bound to eIF2-gammaDIII domain | Descriptor: | Cell division cycle protein 123, Eukaryotic translation initiation factor 2 subunit gamma | Authors: | Panvert, M, Dubiez, E, Arnold, L, Perez, J, Seufert, W, Mechulam, Y, Schmitt, E. | Deposit date: | 2015-04-23 | Release date: | 2015-10-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Cdc123, a Cell Cycle Regulator Needed for eIF2 Assembly, Is an ATP-Grasp Protein with Unique Features. Structure, 23, 2015
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7MG7
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![BU of 7mg7 by Molmil](/molmil-images/mine/7mg7) | Concanavalin A bound to a DNA glycoconjugate, Man-GTAC | Descriptor: | 3-{[2-(2-hydroxyethoxy)ethyl]amino}-4-[(6-hydroxyhexyl)amino]cyclobut-3-ene-1,2-dione, CALCIUM ION, Concanavalin-A, ... | Authors: | Partridge, B.E, Winegar, P.H, Mirkin, C.A. | Deposit date: | 2021-04-12 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Redefining Protein Interfaces within Protein Single Crystals with DNA. J.Am.Chem.Soc., 143, 2021
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7MGD
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![BU of 7mgd by Molmil](/molmil-images/mine/7mgd) | Concanavalin A bound to a DNA glycoconjugate, T(Man-T)TT | Descriptor: | CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ... | Authors: | Partridge, B.E, Winegar, P.H, Mirkin, C.A. | Deposit date: | 2021-04-12 | Release date: | 2021-06-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Redefining Protein Interfaces within Protein Single Crystals with DNA. J.Am.Chem.Soc., 143, 2021
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