7AIQ
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![BU of 7aiq by Molmil](/molmil-images/mine/7aiq) | Structure of Human Potassium Chloride Transporter KCC1 in NaCl (Subclass 1) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-TRIPHOSPHATE, Solute carrier family 12 member 4, ... | 著者 | Ebenhoch, R, Chi, G, Man, H, Wang, D, McKinley, G, Mukhopadhyay, S.M.M, MacLean, E.M, Chalk, R, Moreau, C, Snee, M, Bohstedt, T, Singh, N.K, Abrusci, P, Liko, I, Tehan, B.G, Almeida, F.G, Arrowsmith, C.H, Tang, H, Robinson, C.V, Bountra, C, Edwards, A.M, Marsden, B.D, Burgess-Brown, N.A, Duerr, K.L, Structural Genomics Consortium (SGC) | 登録日 | 2020-09-28 | 公開日 | 2021-06-02 | 最終更新日 | 2021-07-28 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Phospho-regulation, nucleotide binding and ion access control in potassium-chloride cotransporters. Embo J., 40, 2021
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2IZU
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![BU of 2izu by Molmil](/molmil-images/mine/2izu) | Structure of casein kinase gamma 3 in complex with inhibitor | 分子名称: | 1,2-ETHANEDIOL, 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, CASEIN KINASE I ISOFORM GAMMA-3, ... | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | 登録日 | 2006-07-26 | 公開日 | 2006-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Inhibitor Binding by Casein Kinases To be Published
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5Y7H
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2J2J
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![BU of 2j2j by Molmil](/molmil-images/mine/2j2j) | Canine adenovirus fibre head at 1.5 A resolution | 分子名称: | FIBER PROTEIN | 著者 | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | 登録日 | 2006-08-16 | 公開日 | 2006-09-18 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor. J.Biol.Chem., 281, 2006
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3FOE
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![BU of 3foe by Molmil](/molmil-images/mine/3foe) | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | 分子名称: | 7-[(3R)-3-aminopyrrolidin-1-yl]-8-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, DNA (5'-D(P*AP*CP*CP*AP*AP*GP*GP*TP*CP*AP*TP*GP*AP*AP*T)-3'), DNA (5'-D(P*AP*GP*TP*CP*AP*TP*TP*CP*AP*TP*GP*AP*CP*CP*TP*TP*GP*GP*T)-3'), ... | 著者 | Laponogov, I, Sohi, M.K, Veselkov, D.A, Pan, X.-S, Sawhney, R, Thompson, A.W, McAuley, K.E, Fisher, L.M, Sanderson, M.R. | 登録日 | 2008-12-30 | 公開日 | 2009-02-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (4.001 Å) | 主引用文献 | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases Nat.Struct.Mol.Biol., 16, 2009
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1BO5
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![BU of 1bo5 by Molmil](/molmil-images/mine/1bo5) | CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN ESCHERICHIA COLI GLYCEROL KINASE AND THE ALLOSTERIC REGULATOR FRUCTOSE 1,6-BISPHOSPHATE. | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, GLYCEROL, PROTEIN (GLYCEROL KINASE) | 著者 | Ormo, M, Bystrom, C.E, Remington, S.J. | 登録日 | 1998-08-10 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structure of a complex of Escherichia coli glycerol kinase and an allosteric effector fructose 1,6-bisphosphate. Biochemistry, 37, 1998
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5BWH
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![BU of 5bwh by Molmil](/molmil-images/mine/5bwh) | Structure of H200C variant of Homoprotocatechuate 2,3-Dioxygenase from B.fuscum in complex with HPCA at 1.46 Ang resolution | 分子名称: | 2-(3,4-DIHYDROXYPHENYL)ACETIC ACID, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kovaleva, E.G, Lipscomb, J.D. | 登録日 | 2015-06-08 | 公開日 | 2015-10-28 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | 主引用文献 | A Long-Lived Fe(III)-(Hydroperoxo) Intermediate in the Active H200C Variant of Homoprotocatechuate 2,3-Dioxygenase: Characterization by Mossbauer, Electron Paramagnetic Resonance, and Density Functional Theory Methods. Inorg.Chem., 54, 2015
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5IFJ
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![BU of 5ifj by Molmil](/molmil-images/mine/5ifj) | Crystal structure of anti-gliadin 1002-1E01 Fab fragment in complex of peptide PLQPEQPFP | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain, SULFATE ION, ... | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | 登録日 | 2016-02-26 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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1K08
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![BU of 1k08 by Molmil](/molmil-images/mine/1k08) | Crystallographic Binding Study of 10 mM N-benzoyl-N'-beta-D-glucopyranosyl urea to glycogen phosphorylase b | 分子名称: | Glycogen Phosphorylase, N-[(phenylcarbonyl)carbamoyl]-beta-D-glucopyranosylamine, PYRIDOXAL-5'-PHOSPHATE | 著者 | Oikonomakos, N.G, Kosmopoulou, M, Zographos, S.E, Leonidas, D.D, Chrysina, E.D, Somsak, L, Nagy, V, Praly, J.P, Docsa, T, Toth, B, Gergely, P. | 登録日 | 2001-09-18 | 公開日 | 2001-10-03 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies. Eur.J.Biochem., 269, 2002
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2IXD
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![BU of 2ixd by Molmil](/molmil-images/mine/2ixd) | Crystal structure of the putative deacetylase BC1534 from Bacillus cereus | 分子名称: | ACETATE ION, LMBE-RELATED PROTEIN, ZINC ION | 著者 | Fadouloglou, V.E, Bouriotis, V, Kokkinidis, M. | 登録日 | 2006-07-07 | 公開日 | 2007-07-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of the Bczbp, a Zinc-Binding Protein from Bacillus Cereus FEBS J., 274, 2007
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2IZT
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![BU of 2izt by Molmil](/molmil-images/mine/2izt) | Structure of casein kinase gamma 3 in complex with inhibitor | 分子名称: | CASEIN KINASE I ISOFORM GAMMA-3, CHLORIDE ION, N2-[(1R,2S)-2-AMINOCYCLOHEXYL]-N6-(3-CHLOROPHENYL)-9-ETHYL-9H-PURINE-2,6-DIAMINE | 著者 | Bunkoczi, G, Salah, E, Rellos, P, Das, S, Fedorov, O, Savitsky, P, Debreczeni, J.E, Gileadi, O, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S. | 登録日 | 2006-07-26 | 公開日 | 2006-08-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Inhibitor Binding by Casein Kinases To be Published
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5IH8
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![BU of 5ih8 by Molmil](/molmil-images/mine/5ih8) | MELK in complex with NVS-MELK1 | 分子名称: | Maternal embryonic leucine zipper kinase, N-[(pyridin-2-yl)methyl]-4-[4-(pyridin-4-yl)-1H-pyrazol-1-yl]benzamide | 著者 | Sprague, E.R, Puleo, D.E. | 登録日 | 2016-02-29 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J.Med.Chem., 59, 2016
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6UXX
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![BU of 6uxx by Molmil](/molmil-images/mine/6uxx) | PRMT5:MEP50 Complexed with Allosteric Inhibitor Compound 1a | 分子名称: | (5R)-2-amino-5-(4-methoxyphenyl)-3-methyl-5-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]decan-1-yl]-3,5-dihydro-4H-imidazol-4-one, Methylosome protein 50, Protein arginine N-methyltransferase 5 | 著者 | Palte, R.L, Schneider, S.E. | 登録日 | 2019-11-08 | 公開日 | 2020-08-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5). Acs Med.Chem.Lett., 11, 2020
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2J1K
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![BU of 2j1k by Molmil](/molmil-images/mine/2j1k) | CAV-2 fibre head in complex with CAR D1 | 分子名称: | COXSACKIEVIRUS AND ADENOVIRUS RECEPTOR, FIBER PROTEIN | 著者 | Seiradake, E, Lortat-Jacob, H, Billet, O, Kremer, E.J, Cusack, S. | 登録日 | 2006-08-14 | 公開日 | 2006-09-05 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural and Mutational Analysis of Human Ad37 and Canine Adenovirus 2 Fiber Heads in Complex with the D1 Domain of Coxsackie and Adenovirus Receptor. J.Biol.Chem., 281, 2006
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7KF1
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1O5A
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![BU of 1o5a by Molmil](/molmil-images/mine/1o5a) | Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) | 分子名称: | 3-{5-[AMINO(IMINIO)METHYL]-1H-INDOL-2-YL}-1,1'-BIPHENYL-2-OLATE, CITRIC ACID, Urokinase-type plasminogen activator | 著者 | Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. | 登録日 | 2003-09-09 | 公開日 | 2004-09-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA) J.Mol.Biol., 344, 2004
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7KGZ
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5IH9
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![BU of 5ih9 by Molmil](/molmil-images/mine/5ih9) | MELK in complex with NVS-MELK8A | 分子名称: | 1-methyl-4-[4-(4-{3-[(piperidin-4-yl)methoxy]pyridin-4-yl}-1H-pyrazol-1-yl)phenyl]piperazine, Maternal embryonic leucine zipper kinase | 著者 | Sprague, E.R, Puleo, D.E. | 登録日 | 2016-02-29 | 公開日 | 2016-06-01 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight. J.Med.Chem., 59, 2016
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2BR2
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![BU of 2br2 by Molmil](/molmil-images/mine/2br2) | RNase PH core of the archaeal exosome | 分子名称: | CHLORIDE ION, EXOSOME COMPLEX EXONUCLEASE 1, EXOSOME COMPLEX EXONUCLEASE 2 | 著者 | lorentzen, E, Fribourg, S, Conti, E. | 登録日 | 2005-04-30 | 公開日 | 2005-06-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The Archaeal Exosome Core is a Hexameric Ring Structure with Three Catalytic Subunits. Nat.Struct.Mol.Biol., 12, 2005
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1T4P
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![BU of 1t4p by Molmil](/molmil-images/mine/1t4p) | Arginase-dehydro-ABH complex | 分子名称: | Arginase 1, MANGANESE (II) ION, [(1E,5S)-5-AMINO-5-CARBOXYPENT-1-ENYL](TRIHYDROXY)BORATE(1-) | 著者 | Cama, E, Pethe, S, Boucher, J.-L, Han, S, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W. | 登録日 | 2004-04-30 | 公開日 | 2005-04-12 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Inhibitor coordination interactions in the binuclear manganese cluster of arginase Biochemistry, 43, 2004
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5IIK
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![BU of 5iik by Molmil](/molmil-images/mine/5iik) | Crystal structure of the post-catalytic nick complex of DNA polymerase lambda with a templating 8-oxo-dG and incorporated dC | 分子名称: | CITRIC ACID, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*(8OG)P*TP*AP*CP*TP*G)-3'), ... | 著者 | Burak, M.J, Guja, K.E, Garcia-Diaz, M. | 登録日 | 2016-03-01 | 公開日 | 2016-08-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.982 Å) | 主引用文献 | A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG. Embo J., 35, 2016
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1O5B
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![BU of 1o5b by Molmil](/molmil-images/mine/1o5b) | Dissecting and Designing Inhibitor Selectivity Determinants at the S1 site Using an Artificial Ala190 Protease (Ala190 uPA) | 分子名称: | 4-IODOBENZO[B]THIOPHENE-2-CARBOXAMIDINE, CITRIC ACID, Urokinase-type plasminogen activator | 著者 | Katz, B.A, Luong, C, Ho, J.D, Somoza, J.R, Gjerstad, E, Tang, J, Williams, S.R, Verner, E, Mackman, R.L, Young, W.B, Sprengeler, P.A, Chan, H, Mortara, K, Janc, J.W, McGrath, M.E. | 登録日 | 2003-09-09 | 公開日 | 2004-09-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Dissecting and designing inhibitor selectivity determinants at the S1 site using an artificial Ala190 protease (Ala190 uPA) J.Mol.Biol., 344, 2004
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5IK8
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![BU of 5ik8 by Molmil](/molmil-images/mine/5ik8) | Laminin A2LG45 I-form, G6/7 bound. | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7-hydroxy-4-methyl-2H-chromen-2-one, ... | 著者 | Briggs, D.C, Hohenester, E, Campbell, K.P. | 登録日 | 2016-03-03 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis of laminin binding to the LARGE glycans on dystroglycan. Nat.Chem.Biol., 12, 2016
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7AH0
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![BU of 7ah0 by Molmil](/molmil-images/mine/7ah0) | Crystal structure of the de novo designed two-heme binding protein, 4D2 | 分子名称: | 4D2, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hutchins, G.H, Parnell, A.E, Anderson, J.L.R. | 登録日 | 2020-09-23 | 公開日 | 2021-10-06 | 最終更新日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | 主引用文献 | An expandable, modular de novo protein platform for precision redox engineering. Proc.Natl.Acad.Sci.USA, 120, 2023
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2BNQ
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![BU of 2bnq by Molmil](/molmil-images/mine/2bnq) | Structural and kinetic basis for heightened immunogenicity of T cell vaccines | 分子名称: | BETA-2-MICROGLOBULIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, SYNTHETIC PEPTIDE, ... | 著者 | Chen, J.-L, Stewart-Jones, G, Bossi, G, Lissin, N.M, Wooldridge, L, Choi, E.M.L, Held, G, Dunbar, P.R, Esnouf, R.M, Sami, M, Boultier, J.M, Rizkallah, P.J, Renner, C, Sewell, A, van der Merwe, P.A, Jackobsen, B.K, Griffiths, G, Jones, E.Y, Cerundolo, V. | 登録日 | 2005-03-31 | 公開日 | 2005-05-23 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Kinetic Basis for Heightened Immunogenicity of T Cell Vaccines J.Exp.Med., 201, 2005
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