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2IZU

Structure of casein kinase gamma 3 in complex with inhibitor

Summary for 2IZU
Entry DOI10.2210/pdb2izu/pdb
Related2CHL 2IUR 2IZS 2IZT
DescriptorCASEIN KINASE I ISOFORM GAMMA-3, 2-({6-[(3-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywordsserine/threonine-protein kinase, kinase, transferase, atp- binding, phosphorylation, nucleotide-binding, wnt signaling pathway, serine/threonine kinase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm: Q9Y6M4
Total number of polymer chains1
Total formula weight39103.33
Authors
Primary citationBunkoczi, G.,Salah, E.,Rellos, P.,Das, S.,Fedorov, O.,Savitsky, P.,Debreczeni, J.E.,Gileadi, O.,Sundstrom, M.,Edwards, A.,Arrowsmith, C.,Weigelt, J.,von Delft, F.,Knapp, S.
Inhibitor Binding by Casein Kinases
To be Published,
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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PDB entries from 2024-04-24

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