3FOE

Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases

Summary for 3FOE

• Entry DOI: 10.2210/pdb3foe/pdb
• Related: 2NOV 3FOF
• Descriptor: DNA topoisomerase 4 subunit A, DNA topoisomerase 4 subunit B, DNA (5'-D(P*AP*CP*CP*AP*AP*GP*GP*TP*CP*AP*TP*GP*AP*AP*T)-3'), ... (7 entities in total)
• Functional Keywords: quinolone, topoisomerase, dna, protein-dna cleavage complex, streptococcus pneumoniae, clinafloxacin, cell membrane, dna-binding, isomerase, membrane, atp-binding, nucleotide-binding, isomerase-dna complex, isomerase/dna
• Biological source: Streptococcus pneumoniae; More
• Cellular location: Cell membrane; Peripheral membrane protein (By similarity): P72525
• Total number of polymer chains: 8
• Total formula weight: 195299.44

Authors

Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R. (deposition date: 2008-12-30, release date: 2009-02-24, Last modification date: 2023-11-01)

• Primary citation: Laponogov, I.,Sohi, M.K.,Veselkov, D.A.,Pan, X.-S.,Sawhney, R.,Thompson, A.W.,McAuley, K.E.,Fisher, L.M.,Sanderson, M.R.; Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases; Nat.Struct.Mol.Biol., 16:667-669, 2009; PubMed: 19448616; DOI: 10.1038/nsmb.1604

Experimental method

X-RAY DIFFRACTION (4.001 Å)