7KGZ
FMN-binding beta-glucuronidase from Roseburia hominis
Summary for 7KGZ
Entry DOI | 10.2210/pdb7kgz/pdb |
Descriptor | Beta-glucuronidase, CALCIUM ION, FLAVIN MONONUCLEOTIDE, ... (5 entities in total) |
Functional Keywords | beta-glucuronidase, gut microbial enzyme, fmn, hydrolase |
Biological source | Roseburia hominis |
Total number of polymer chains | 2 |
Total formula weight | 167770.74 |
Authors | Walker, M.E.,Redinbo, M.R. (deposition date: 2020-10-19, release date: 2021-11-10, Last modification date: 2023-10-18) |
Primary citation | Zhang, J.,Walker, M.E.,Sanidad, K.Z.,Zhang, H.,Liang, Y.,Zhao, E.,Chacon-Vargas, K.,Yeliseyev, V.,Parsonnet, J.,Haggerty, T.D.,Wang, G.,Simpson, J.B.,Jariwala, P.B.,Beaty, V.V.,Yang, J.,Yang, H.,Panigrahy, A.,Minter, L.M.,Kim, D.,Gibbons, J.G.,Liu, L.,Li, Z.,Xiao, H.,Borlandelli, V.,Overkleeft, H.S.,Cloer, E.W.,Major, M.B.,Goldfarb, D.,Cai, Z.,Redinbo, M.R.,Zhang, G. Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract. Nat Commun, 13:136-136, 2022 Cited by PubMed: 35013263DOI: 10.1038/s41467-021-27762-y PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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