3G40
 
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2EXW
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2EXY
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2EZ0
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8B42
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8B8G
 | | Cryo-EM structure of Ca2+-free mTMEM16F F518H mutant in Digitonin | | Descriptor: | Anoctamin-6 | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8K
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin closed/closed | | Descriptor: | 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.01 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8J
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518H mutant in Digitonin | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.96 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8BC0
 | | Cryo-EM structure of Ca2+-bound mTMEM16F F518A Q623A mutant in GDN open/closed | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-16 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B8M
 | | Cryo-EM structure of Ca2+-bound mTMEM16F N562A mutant in Digitonin open/closed | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-16 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.49 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8BC1
 | | Cryo-EM Structure of Ca2+-bound mTMEM16F F518A_Q623A mutant in GDN | | Descriptor: | Anoctamin-6,mTMEM16F, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-14 | | Release date: | 2022-11-16 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.93 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8B40
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8BEN
 | | LRR domain Structure of the LRRC8C protein | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Sawicka, M, Dutzler, R. | | Deposit date: | 2022-10-21 | | Release date: | 2022-12-14 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structure of a volume-regulated heteromeric LRRC8A/C channel.
Nat.Struct.Mol.Biol., 30, 2023
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8B41
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8B8Q
 | | Structure of mTMEM16F in lipid Nanodiscs in the presence of Ca2+ | | Descriptor: | Anoctamin-6, CALCIUM ION | | Authors: | Arndt, M, Alvadia, C, Straub, M.S, Clerico-Mosina, V, Paulino, C, Dutzler, R. | | Deposit date: | 2022-10-04 | | Release date: | 2022-12-21 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (2.94 Å) | | Cite: | Structural basis for the activation of the lipid scramblase TMEM16F.
Nat Commun, 13, 2022
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8C03
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy12 in outward-facing conformation | | Descriptor: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, Solute carrier family 40 member 1 | | Authors: | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | Deposit date: | 2022-12-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.89 Å) | | Cite: | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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8BZY
 | | Structure of SLC40/ferroportin in complex with vamifeport and synthetic nanobody Sy3 in occluded conformation | | Descriptor: | 2-[2-[2-(1~{H}-benzimidazol-2-yl)ethylamino]ethyl]-~{N}-[(3-fluoranylpyridin-2-yl)methyl]-1,3-oxazole-4-carboxamide, DIUNDECYL PHOSPHATIDYL CHOLINE, Solute carrier family 40 member 1, ... | | Authors: | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | Deposit date: | 2022-12-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.24 Å) | | Cite: | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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8C02
 | | Structure of SLC40/ferroportin in complex with synthetic nanobody Sy3 in occluded conformation | | Descriptor: | Solute carrier family 40 member 1, Sybody3 | | Authors: | Lehmann, E.F, Liziczai, M, Drozdzyk, K, Dutzler, R, Manatschal, C. | | Deposit date: | 2022-12-15 | | Release date: | 2023-03-22 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (4.09 Å) | | Cite: | Structures of ferroportin in complex with its specific inhibitor vamifeport.
Elife, 12, 2023
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7QIA
 | | Structure of apo-EleNRMT in complex with two nanobodies at 3.5A | | Descriptor: | Divalent metal cation transporter, Nanobody 1, Nanobody 2 | | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | Deposit date: | 2021-12-14 | | Release date: | 2021-12-29 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QIC
 | | Structure of magnesium-bound EleNRMT in complex with two nanobodies at 4.1A | | Descriptor: | Divalent metal cation transporter, MAGNESIUM ION, Nanobody 1, ... | | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | Deposit date: | 2021-12-14 | | Release date: | 2021-12-29 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.1 Å) | | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QJI
 | | X-Ray Structure of apo-EleNRMT in complex with two Nanobodies at 4.1A | | Descriptor: | Divalent metal cation transporter, Elen-Nanobody-complex | | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | Deposit date: | 2021-12-16 | | Release date: | 2022-02-02 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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7QJJ
 | | X-Ray Structure of a Mn2+ soak of EleNRMT in complex with two Nanobodies at 4.6A | | Descriptor: | Divalent metal cation transporter, Elen-Nb1-Nb2, MANGANESE (II) ION | | Authors: | Ramanadane, K, Straub, M.S, Dutzler, R, Manatschal, C. | | Deposit date: | 2021-12-16 | | Release date: | 2022-02-02 | | Last modified: | 2024-10-16 | | Method: | X-RAY DIFFRACTION (4.6 Å) | | Cite: | Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family.
Elife, 11, 2022
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2PFI
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8RTS
 | | Structure of a homomeric human LRRC8C Volume-Regulated Anion Channel | | Descriptor: | Volume-regulated anion channel subunit LRRC8C | | Authors: | Rutz, S, Quinodoz, M, Peter, V, Garavelli, L, Innes, M, Kellenberger, S, Barone, A, Campos-Xavier, B, Unger, S, Rivolta, C, Dutzler, R, Superti-Furga, A. | | Deposit date: | 2024-01-29 | | Release date: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.73 Å) | | Cite: | Genetic activation of a Volume-Regulated Anion Channel yields a multisystem disorder
To Be Published
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8QZC
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