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8RTS

Structure of a homomeric human LRRC8C Volume-Regulated Anion Channel

This is a non-PDB format compatible entry.
Summary for 8RTS
Entry DOI10.2210/pdb8rts/pdb
EMDB information19495
DescriptorVolume-regulated anion channel subunit LRRC8C (1 entity in total)
Functional Keywordsanion channel, volume regulation, membrane protein
Biological sourceHomo sapiens (human)
Total number of polymer chains7
Total formula weight654138.95
Authors
Rutz, S.,Quinodoz, M.,Peter, V.,Garavelli, L.,Innes, M.,Kellenberger, S.,Barone, A.,Campos-Xavier, B.,Unger, S.,Rivolta, C.,Dutzler, R.,Superti-Furga, A. (deposition date: 2024-01-29, release date: 2024-11-13, Last modification date: 2024-11-27)
Primary citationRutz, S.,Quinodoz, M.,Peter, V.,Garavelli, L.,Innes, M.,Kellenberger, S.,Barone, A.,Campos-Xavier, B.,Unger, S.,Rivolta, C.,Dutzler, R.,Superti-Furga, A.
Genetic activation of a Volume-Regulated Anion Channel yields a multisystem disorder
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.73 Å)
Structure validation

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