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PDB: 82 件

4RLJ
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Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis
分子名称: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-17
公開日2015-10-21
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
4RLT
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Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis complexed with Fisetin
分子名称: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,7,3',4'-TETRAHYDROXYFLAVONE, ...
著者Li, J, Dong, Y, Rao, Z.H.
登録日2014-10-18
公開日2015-10-21
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.049 Å)
主引用文献Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.
Protein Cell, 6, 2015
1REO
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L-amino acid oxidase from Agkistrodon halys pallas
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, AHPLAAO, CITRIC ACID, ...
著者Zhang, H, Teng, M, Niu, L, Wang, Y, Wang, Y, Liu, Q, Huang, Q, Hao, Q, Dong, Y, Liu, P.
登録日2003-11-07
公開日2004-05-04
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Purification, partial characterization, crystallization and structural determination of AHP-LAAO, a novel L-amino-acid oxidase with cell apoptosis-inducing activity from Agkistrodon halys pallas venom.
Acta Crystallogr.,Sect.D, 60, 2004
4AYW
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (PLATE FORM)
分子名称: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CHOLESTEROL HEMISUCCINATE, DODECYL-BETA-D-MALTOSIDE, ...
著者Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
8IKJ
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Cryo-EM structure of the inactive CD97
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Adhesion G protein-coupled receptor E5,Soluble cytochrome b562,Adhesion G protein-coupled receptor E5 subunit beta
著者Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P, Guo, J, Qin, J, Shen, D, Ji, S, Zang, S, Zhang, H, Wang, W, Shen, Q, Sun, P, Zhang, Y.
登録日2023-02-28
公開日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
4AYX
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10 (ROD FORM B)
分子名称: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
著者Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
4AYT
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STRUCTURE OF THE HUMAN MITOCHONDRIAL ABC TRANSPORTER, ABCB10
分子名称: ATP-BINDING CASSETTE SUB-FAMILY B MEMBER 10 MITOCHONDRIAL, CARDIOLIPIN, DODECYL-BETA-D-MALTOSIDE, ...
著者Pike, A.C.W, Shintre, C.A, Li, Q, Kim, J, von Delft, F, Barr, A.J, Das, S, Chaikuad, A, Xia, X, Quigley, A, Dong, Y, Dong, L, Krojer, T, Vollmar, M, Muniz, J.R.C, Bray, J.E, Berridge, G, Chalk, R, Gileadi, O, Burgess-Brown, N, Shrestha, L, Goubin, S, Yang, J, Mahajan, P, Mukhopadhyay, S, Bullock, A.N, Arrowsmith, C.H, Weigelt, J, Bountra, C, Edwards, A.M, Carpenter, E.P.
登録日2012-06-22
公開日2012-07-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structures of Abcb10, a Human ATP-Binding Cassette Transporter in Apo- and Nucleotide-Bound States
Proc.Natl.Acad.Sci.USA, 110, 2013
1LSL
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Crystal Structure of the Thrombospondin-1 Type 1 Repeats
分子名称: Thrombospondin 1, alpha-L-fucopyranose, beta-L-fucopyranose
著者Tan, K, Duquette, M, Liu, J, Dong, Y, Zhang, R, Joachimiak, A, Lawler, J, Wang, J.-H.
登録日2002-05-17
公開日2002-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the TSP-1 type 1 repeats: a novel layered fold and its biological implication.
J.Cell Biol., 159, 2002
8IKL
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Cryo-EM structure of the CD97-G13 complex
分子名称: Adhesion G protein-coupled receptor E5, Guanine nucleotide-binding protein G(13) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Mao, C, Zhao, R, Dong, Y, Gao, M, Chen, L, Zhang, C, Xiao, P.
登録日2023-02-28
公開日2024-01-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.33 Å)
主引用文献Conformational transitions and activation of the adhesion receptor CD97.
Mol.Cell, 84, 2024
4XO1
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crystal structure of Se-Met GnsA with double mutations
分子名称: Protein GnsA
著者Zhan, L, Gao, Z, Dong, Y.
登録日2015-01-16
公開日2015-07-29
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Crystal structure of GnsA from Escherichia coli
Biochem.Biophys.Res.Commun., 462, 2015
3Q5M
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Crystal structure of Escherichia coli BamD
分子名称: IODIDE ION, UPF0169 lipoprotein yfiO
著者Dong, C, Hou, H, Yang, X, Dong, Y, Shen, Y.
登録日2010-12-28
公開日2011-12-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.604 Å)
主引用文献Structure of Escherichia coli BamD and its functional implications in outer membrane protein assembly
Acta Crystallogr.,Sect.D, 68, 2012
6ITW
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Crystal structure of Atu4351 from Agrobacterium tumefaciens
分子名称: Type VI immunity protein Atu4351
著者Shi, L, Gao, Z, Zhang, H, Dong, Y.
登録日2018-11-26
公開日2019-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the type VI immunity protein Tdi1 (Atu4351) from Agrobacterium tumefaciens.
Acta Crystallogr F Struct Biol Commun, 75, 2019
5ID3
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Solution structure of the pore-forming region of C. elegans Mitochondrial Calcium Uniporter (MCU)
分子名称: Mitochondrial Calcium Uniporter
著者Oxenoid, K, Dong, Y, Cao, C, Cui, T, Sancak, Y, Markhard, A.L, Grabarek, Z, Kong, L, Liu, Z, Ouyang, B, Cong, Y, Mootha, V.K, Chou, J.J, Membrane Protein Structures by Solution NMR (MPSbyNMR)
登録日2016-02-23
公開日2016-05-04
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Architecture of the mitochondrial calcium uniporter.
Nature, 533, 2016
4ZWJ
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Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
分子名称: Chimera protein of human Rhodopsin, mouse S-arrestin, and T4 Endolysin
著者Kang, Y, Zhou, X.E, Gao, X, He, Y, Liu, W, Ishchenko, A, Barty, A, White, T.A, Yefanov, O, Han, G.W, Xu, Q, de Waal, P.W, Ke, J, Tan, M.H.E, Zhang, C, Moeller, A, West, G.M, Pascal, B, Eps, N.V, Caro, L.N, Vishnivetskiy, S.A, Lee, R.J, Suino-Powell, K.M, Gu, X, Pal, K, Ma, J, Zhi, X, Boutet, S, Williams, G.J, Messerschmidt, M, Gati, C, Zatsepin, N.A, Wang, D, James, D, Basu, S, Roy-Chowdhury, S, Conrad, C, Coe, J, Liu, H, Lisova, S, Kupitz, C, Grotjohann, I, Fromme, R, Jiang, Y, Tan, M, Yang, H, Li, J, Wang, M, Zheng, Z, Li, D, Howe, N, Zhao, Y, Standfuss, J, Diederichs, K, Dong, Y, Potter, C.S, Carragher, B, Caffrey, M, Jiang, H, Chapman, H.N, Spence, J.C.H, Fromme, P, Weierstall, U, Ernst, O.P, Katritch, V, Gurevich, V.V, Griffin, P.R, Hubbell, W.L, Stevens, R.C, Cherezov, V, Melcher, K, Xu, H.E, GPCR Network (GPCR)
登録日2015-05-19
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.302 Å)
主引用文献Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Nature, 523, 2015
5HW4
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Crystal structure of Escherichia coli 16S rRNA methyltransferase RsmI in complex with AdoMet
分子名称: Ribosomal RNA small subunit methyltransferase I, S-ADENOSYLMETHIONINE
著者Zhao, M, Zhang, H, Dong, Y, Gong, Y.
登録日2016-01-28
公開日2016-10-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.211 Å)
主引用文献Structural Insights into the Methylation of C1402 in 16S rRNA by Methyltransferase RsmI
Plos One, 11, 2016
8SPB
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Caspase-4/Pro-IL-18 complex
分子名称: Caspase-4 subunit p10, Caspase-4 subunit p20, Interleukin-18
著者Pascal, D, Dong, Y, Wu, H, Jon, K.
登録日2023-05-02
公開日2023-11-22
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into cytokine cleavage by inflammatory caspase-4.
Nature, 624, 2023
2MA1
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Solution structure of HRDC1 domain of RecQ helicase from Deinococcus radiodurans
分子名称: DNA helicase RecQ
著者Liu, S, Zhang, W, Gao, Z, Ming, Q, Hou, H, Lan, W, Wu, H, Cao, C, Dong, Y.
登録日2013-06-24
公開日2013-07-10
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of the N-terminal-most HRDC1 domain of RecQ helicase from Deinococcus radiodurans
To be Published
3O5X
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Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor
分子名称: 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11
著者Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J.
登録日2010-07-28
公開日2010-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
J.Med.Chem., 53, 2010
2LH8
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Syrian hamster prion protein with thiamine
分子名称: 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Major prion protein
著者Perez-Pineiro, R, Bjorndahl, T.C, Berjanskii, M, Hau, D, Li, L, Huang, A, Lee, R, Gibbs, E, Ladner, C, Wei Dong, Y, Abera, A, Cashman, N.R, Wishart, D.
登録日2011-08-05
公開日2011-09-14
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献The prion protein binds thiamine.
Febs J., 278, 2011
4LX3
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Conserved Residues that Modulate Protein trans-Splicing of Npu DnaE Split Intein
分子名称: DNA polymerase III, alpha subunit, Nucleic acid binding, ...
著者Wu, Q, Gao, Z, Wei, Y, Ma, G, Zheng, Y, Dong, Y, Liu, Y.
登録日2013-07-29
公開日2014-06-25
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Conserved residues that modulate protein trans-splicing of Npu DnaE split intein.
Biochem.J., 461, 2014
5YIK
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Structure of a Legionella effector with its substrate
分子名称: SdeA, ubiquitin
著者Feng, Y, Dong, Y, Liu, Z.
登録日2017-10-05
公開日2018-05-30
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018
4MZ7
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Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ...
著者Zhu, C, Gao, W, Zhao, K, Qin, X, Zhang, Y, Peng, X, Zhang, L, Dong, Y, Zhang, W, Li, P, Wei, W, Gong, Y, Yu, X.F.
登録日2013-09-29
公開日2013-11-20
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase
Nat Commun, 4, 2013
4MMJ
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crystal structure of YafQ from E.coli strain BL21(DE3)
分子名称: Addiction module toxin, RelE/StbE family, SULFATE ION
著者Liang, Y, Gao, Z, Liu, Q, Dong, Y.
登録日2013-09-09
公開日2014-06-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Functional Characterization of Escherichia coli Toxin-Antitoxin Complex DinJ-YafQ
J.Biol.Chem., 289, 2014
2EXX
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Crystal structure of HSCARG from Homo sapiens in complex with NADP
分子名称: GLYCEROL, HSCARG protein, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Dai, X, Chen, Q, Yao, D, Liang, Y, Dong, Y, Gu, X, Zheng, X, Luo, M.
登録日2005-11-09
公開日2006-11-21
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Restructuring of the dinucleotide-binding fold in an NADP(H) sensor protein.
Proc.Natl.Acad.Sci.USA, 104, 2007
5YIM
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Structure of a Legionella effector
分子名称: SdeA
著者Feng, Y, Dong, Y, Wang, W.
登録日2017-10-05
公開日2018-05-30
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (3.394 Å)
主引用文献Structural basis of ubiquitin modification by the Legionella effector SdeA.
Nature, 557, 2018

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