4RLJ

Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis

Summary for 4RLJ

• Entry DOI: 10.2210/pdb4rlj/pdb
• Related: 4RLT 4RLU 4RLW
• Descriptor: (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, GLYCEROL, ... (7 entities in total)
• Functional Keywords: double hotdog fold, (3r)-hydroxyacyl-acp binding, lyase
• Biological source: Mycobacterium tuberculosis H37Rv; More
• Total number of polymer chains: 2
• Total formula weight: 34002.14

Authors

Li, J.,Dong, Y.,Rao, Z.H. (deposition date: 2014-10-17, release date: 2015-10-21, Last modification date: 2024-02-28)

• Primary citation: Dong, Y.,Qiu, X.,Shaw, N.,Xu, Y.,Sun, Y.,Li, X.,Li, J.,Rao, Z.; Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors.; Protein Cell, 6:504-517, 2015; PubMed: 26081470; DOI: 10.1007/s13238-015-0181-1

Experimental method

X-RAY DIFFRACTION (1.75 Å)