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PDB: 340 results

2H06
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BU of 2h06 by Molmil
Crystal structure of human phosphoribosyl pyrophosphate synthetase 1
Descriptor: Ribose-phosphate pyrophosphokinase I, SULFATE ION
Authors:Li, S, Peng, B, Ding, J.
Deposit date:2006-05-14
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
2H08
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BU of 2h08 by Molmil
crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant Y146M
Descriptor: Ribose-phosphate pyrophosphokinase I, SULFATE ION
Authors:Li, S, Peng, B, Ding, J.
Deposit date:2006-05-14
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
3E9F
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BU of 3e9f by Molmil
Crystal structure short-form (residue1-113) of Eaf3 chromo domain
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Chromatin modification-related protein EAF3
Authors:Sun, B, Hong, J, Zhang, P, Lin, D, Ding, J.
Deposit date:2008-08-22
Release date:2008-11-04
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Molecular Basis of the Interaction of Saccharomyces cerevisiae Eaf3 Chromo Domain with Methylated H3K36
J.Biol.Chem., 283, 2008
1T09
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BU of 1t09 by Molmil
Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP
Descriptor: Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J.
Deposit date:2004-04-08
Release date:2004-06-15
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity
J.Biol.Chem., 279, 2004
2H07
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BU of 2h07 by Molmil
crystal structure of human phosphoribosyl pyrophosphate synthetase 1 mutant S132A
Descriptor: Ribose-phosphate pyrophosphokinase I, SULFATE ION
Authors:Li, S, Peng, B, Ding, J.
Deposit date:2006-05-14
Release date:2006-10-24
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Crystal structure of human phosphoribosylpyrophosphate synthetase 1 reveals a novel allosteric site
Biochem.J., 401, 2007
3RPN
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BU of 3rpn by Molmil
Crystal structure of human kappa class glutathione transferase in complex with S-hexylglutathione
Descriptor: Glutathione S-transferase kappa 1, S-HEXYLGLUTATHIONE
Authors:Wang, B, Peng, Y, Zhang, T, Ding, J.
Deposit date:2011-04-27
Release date:2011-07-13
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
3RIB
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BU of 3rib by Molmil
Human lysine methyltransferase Smyd2 in complex with AdoHcy
Descriptor: N-lysine methyltransferase SMYD2, S-ADENOSYL-L-HOMOCYSTEINE, SULFATE ION, ...
Authors:Xu, S, Zhang, T, Zhong, C, Ding, J.
Deposit date:2011-04-13
Release date:2011-07-20
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.79 Å)
Cite:Structure of human lysine methyltransferase Smyd2 reveals insights into the substrate divergence in Smyd proteins
J Mol Cell Biol, 3, 2011
6KMS
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BU of 6kms by Molmil
Crystal structure of human N6amt1-Trm112 in complex with SAM (space group I422)
Descriptor: Methyltransferase N6AMT1, Multifunctional methyltransferase subunit TRM112-like protein, S-ADENOSYLMETHIONINE
Authors:Li, W.J, Shi, Y, Zhang, T.L, Ye, J, Ding, J.P.
Deposit date:2019-08-01
Release date:2019-09-18
Last modified:2019-11-06
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structural insight into human N6amt1-Trm112 complex functioning as a protein methyltransferase.
Cell Discov, 5, 2019
6KMR
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Crystal structure of human N6amt1-Trm112 in complex with SAM (space group P6122)
Descriptor: 1,2-ETHANEDIOL, Methyltransferase N6AMT1, Multifunctional methyltransferase subunit TRM112-like protein, ...
Authors:Li, W.J, Shi, Y, Zhang, T.L, Ye, J, Ding, J.P.
Deposit date:2019-08-01
Release date:2019-09-18
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural insight into human N6amt1-Trm112 complex functioning as a protein methyltransferase.
Cell Discov, 5, 2019
3GIZ
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BU of 3giz by Molmil
Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab
Descriptor: Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, light chain, ...
Authors:Du, J, Yang, H, Ding, J.
Deposit date:2009-03-07
Release date:2009-05-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20
Mol.Immunol., 46, 2009
5C77
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A novel protein arginine methyltransferase
Descriptor: Protein arginine N-methyltransferase SFM1, S-ADENOSYL-L-HOMOCYSTEINE
Authors:Lv, F, Zhang, T, Ding, J.
Deposit date:2015-06-24
Release date:2016-01-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for Sfm1 functioning as a protein arginine methyltransferase.
Cell Discov, 1, 2015
8JYW
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BU of 8jyw by Molmil
Cryo-EM structure of the gasdermin pore from Trichoplax adhaerens
Descriptor: Gasdermin pore forming domain-containing protein
Authors:Hou, Y.J, Sun, Q, Zeng, H, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
8JYZ
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BU of 8jyz by Molmil
Cryo-EM structure of RCD-1 pore from Neurospora crassa
Descriptor: Gasdermin-like protein rcd-1-1, Gasdermin-like protein rcd-1-2
Authors:Hou, Y.J, Sun, Q, Li, Y, Ding, J.
Deposit date:2023-07-04
Release date:2024-05-01
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.63 Å)
Cite:Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
2OSL
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BU of 2osl by Molmil
Crystal structure of Rituximab Fab in complex with an epitope peptide
Descriptor: B-lymphocyte antigen CD20, heavy chain of the Rituximab Fab fragment,heavy chain of the Rituximab Fab fragment, light chain of the Rituximab Fab fragment,light chain of the Rituximab Fab fragment
Authors:Du, J, Zhong, C, Ding, J.
Deposit date:2007-02-06
Release date:2007-04-10
Last modified:2024-04-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for recognition of CD20 by therapeutic antibody Rituximab
J.Biol.Chem., 282, 2007
2P6G
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BU of 2p6g by Molmil
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
Descriptor: 1-(CYCLOHEXYLAMINO)-3-(6-METHYL-3,4-DIHYDRO-1H-CARBAZOL-9(2H)-YL)PROPAN-2-OL, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:Wu, J, Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6F
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BU of 2p6f by Molmil
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors
Descriptor: (Z)-3-BENZYL-5-(2-HYDROXY-3-NITROBENZYLIDENE)-2-THIOXOTHIAZOLIDIN-4-ONE, Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:Wu, J, Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
2P6E
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BU of 2p6e by Molmil
Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA
Descriptor: Glycylpeptide N-tetradecanoyltransferase, TETRADECANOYL-COA
Authors:Wu, J, Ding, J.
Deposit date:2007-03-18
Release date:2007-06-12
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoyl-CoA and inhibitors reveal the functional roles of the N-terminal region.
J.Biol.Chem., 282, 2007
3EBM
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BU of 3ebm by Molmil
Crystal structure of human translationally controlled tumour associated protein (hTCTP) mutant E12V
Descriptor: Translationally-controlled tumor protein
Authors:Yang, B, Dong, X, Zhong, C, Ding, J.
Deposit date:2008-08-28
Release date:2009-06-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Molecular basis of the acceleration of the GDP-GTP exchange of human ras homolog enriched in brain by human translationally controlled tumor protein.
J.Biol.Chem., 284, 2009
3EOB
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BU of 3eob by Molmil
Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form II
Descriptor: Efalizumab Fab fragment, heavy chain, light chain, ...
Authors:Li, S, Ding, J.
Deposit date:2008-09-26
Release date:2009-04-14
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
3EOA
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BU of 3eoa by Molmil
Crystal structure the Fab fragment of Efalizumab in complex with LFA-1 I domain, Form I
Descriptor: Efalizumab Fab fragment, heavy chain, light chain, ...
Authors:Li, S, Ding, J.
Deposit date:2008-09-26
Release date:2009-04-14
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Efalizumab binding to the LFA-1 alphaL I domain blocks ICAM-1 binding via steric hindrance.
Proc.Natl.Acad.Sci.USA, 106, 2009
3MAR
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BU of 3mar by Molmil
Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP
Descriptor: Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yang, B, Peng, Y, Ding, J.
Deposit date:2010-03-24
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
3MAS
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BU of 3mas by Molmil
Crystal structure of heterodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate
Descriptor: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yang, B, Peng, Y, Ding, J.
Deposit date:2010-03-24
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
3RPP
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BU of 3rpp by Molmil
Crystal structure of human kappa class glutathione transferase in apo form
Descriptor: Glutathione S-transferase kappa 1
Authors:Wang, B, Peng, Y, Zhang, T, Ding, J.
Deposit date:2011-04-27
Release date:2011-07-13
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structures and kinetic studies of human Kappa class glutathione transferase provide insights into the catalytic mechanism.
Biochem.J., 439, 2011
3MAP
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BU of 3map by Molmil
Crystal structure of homodimeric R132H mutant of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex with NADP and isocitrate
Descriptor: ISOCITRIC ACID, Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Yang, B, Peng, Y, Ding, J.
Deposit date:2010-03-24
Release date:2010-11-10
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Molecular mechanisms of "off-on switch" of activities of human IDH1 by tumor-associated mutation R132H.
Cell Res., 20, 2010
5C3Q
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BU of 5c3q by Molmil
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and thymine (T)
Descriptor: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, NICKEL (II) ION, ...
Authors:Li, W, Zhang, T, Ding, J.
Deposit date:2015-06-17
Release date:2015-10-21
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015

221051

数据于2024-06-12公开中

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