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PDB: 340 件
5GRF
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BU of 5grf by Molmil
Crystal structure of the alpha gamma mutant (gamma-K151A) of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5C3R
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BU of 5c3r by Molmil
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-hydroxymethyluracil (5hmU)
分子名称: 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 5-HYDROXYMETHYL URACIL, ...
著者Li, W, Zhang, T, Ding, J.
登録日2015-06-17
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015
5GRE
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BU of 5gre by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
8JDB
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BU of 8jdb by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid
分子名称: (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDD
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BU of 8jdd by Molmil
Crystal structure of H405A mLDHD in apo form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDT
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BU of 8jdt by Molmil
Crystal structure of mLDHD in complex with 2-ketobutanoic acid
分子名称: 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDG
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BU of 8jdg by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxybutanoic acid
分子名称: (2R)-2-oxidanylbutanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-14
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDU
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BU of 8jdu by Molmil
Crystal structure of mLDHD in complex with 2-ketovaleric acid
分子名称: 2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDQ
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BU of 8jdq by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid
分子名称: (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDN
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BU of 8jdn by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid
分子名称: (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDX
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BU of 8jdx by Molmil
Crystal structure of mLDHD in complex with 2-ketoisovaleric acid
分子名称: 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDF
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BU of 8jdf by Molmil
Crystal structure of H405A mLDHD in complex with D-lactate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDC
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BU of 8jdc by Molmil
Crystal structure of mLDHD in apo form
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.696 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDO
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BU of 8jdo by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid
分子名称: (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDZ
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BU of 8jdz by Molmil
Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid
分子名称: (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDS
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BU of 8jds by Molmil
Crystal structure of mLDHD in complex with Pyruvate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.636 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDE
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BU of 8jde by Molmil
Crystal structure of mLDHD in complex with D-lactate
分子名称: FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-13
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.729 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDV
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BU of 8jdv by Molmil
Crystal structure of mLDHD in complex with 2-ketohexanoic acid
分子名称: 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDY
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BU of 8jdy by Molmil
Crystal structure of mLDHD in complex with 2-ketoisocaproic acid
分子名称: 2-OXO-4-METHYLPENTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDP
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BU of 8jdp by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid
分子名称: DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
8JDR
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BU of 8jdr by Molmil
Crystal structure of H405A mLDHD in complex with D-2-hydroxy-3-methyl-valeric acid
分子名称: (2R,3S)-3-methyl-2-oxidanyl-pentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ...
著者Jin, S, Chen, X, Yang, J, Ding, J.
登録日2023-05-15
公開日2023-10-18
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis.
Nat Commun, 14, 2023
5GRI
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BU of 5gri by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+) and citrate
分子名称: CITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, ...
著者Ma, T, Peng, Y, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.31 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
8JYY
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BU of 8jyy by Molmil
Crystal structure of the gasdermin-like protein RCD-1-2 from Neurospora crassa
分子名称: RCD-1-2
著者Li, Y, Hou, Y.J, Ding, J.
登録日2023-07-04
公開日2024-05-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms.
Science, 384, 2024
5GRL
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BU of 5grl by Molmil
Crystal structure of the alpha gamma heterodimer of human IDH3 in complex with Mg(2+), isocitrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ISOCITRIC ACID, Isocitrate dehydrogenase [NAD] subunit alpha, ...
著者Ma, T, Ding, J.
登録日2016-08-11
公開日2017-02-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Molecular mechanism of the allosteric regulation of the alpha gamma heterodimer of human NAD-dependent isocitrate dehydrogenase.
Sci Rep, 7, 2017
5C3S
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BU of 5c3s by Molmil
Crystal structure of the full-length Neurospora crassa T7H in complex with alpha-KG and 5-formyluracil (5fU)
分子名称: 1,2-ETHANEDIOL, 2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde, 2-OXOGLUTARIC ACID, ...
著者Li, W, Zhang, T, Ding, J.
登録日2015-06-17
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi
Nucleic Acids Res., 43, 2015

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件を2024-06-12に公開中

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