7WR1
| P32 of caspase-4 C258A mutant in complex with OspC3 C-terminal ankyrin-repeat domain | 分子名称: | Caspase-4, OspC3 | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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7WR5
| Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+ | 分子名称: | Calmodulin-1, Caspase-4, OspC3, ... | 著者 | Hou, Y.J, Zeng, H, Shao, F, Ding, J. | 登録日 | 2022-01-26 | 公開日 | 2023-01-25 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30, 2023
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3GIZ
| Crystal structure of the Fab fragment of anti-CD20 antibody Ofatumumab | 分子名称: | Fab fragment of anti-CD20 antibody Ofatumumab, heavy chain, light chain, ... | 著者 | Du, J, Yang, H, Ding, J. | 登録日 | 2009-03-07 | 公開日 | 2009-05-26 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the Fab fragment of therapeutic antibody Ofatumumab provides insights into the recognition mechanism with CD20 Mol.Immunol., 46, 2009
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2AJG
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase | 分子名称: | Leucyl-tRNA synthetase | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | 登録日 | 2005-08-01 | 公開日 | 2006-01-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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5H49
| Crystal structure of Cbln1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Cerebellin-1 | 著者 | Zhong, C, Shen, J, Zhang, H, Ding, J. | 登録日 | 2016-10-31 | 公開日 | 2017-09-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cbln1 and Cbln4 Are Structurally Similar but Differ in GluD2 Binding Interactions. Cell Rep, 20, 2017
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2AJH
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with methionine | 分子名称: | Leucyl-tRNA synthetase, METHIONINE | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | 登録日 | 2005-08-02 | 公開日 | 2006-01-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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6LPU
| Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with L-2-hydroxyglutarate (L-2-HG) | 分子名称: | (2S)-2-HYDROXYPENTANEDIOIC ACID, D-2-hydroxyglutarate dehydrogenase, mitochondrial, ... | 著者 | Yang, J, Zhu, H, Ding, J. | 登録日 | 2020-01-12 | 公開日 | 2021-01-13 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | 主引用文献 | Structure, substrate specificity, and catalytic mechanism of human D-2-HGDH and insights into pathogenicity of disease-associated mutations. Cell Discov, 7, 2021
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7X9E
| Crystal structure of the 76E1 Fab in complex with a SARS-CoV-2 spike peptide | 分子名称: | 76E1 Fab Heavy Chain, 76E1 Fab Light Chain, Spike peptide | 著者 | Chen, X, Zhang, T, Ding, J, Sun, X, Sun, B. | 登録日 | 2022-03-15 | 公開日 | 2022-05-11 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol, 7, 2022
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1T09
| Crystal structure of human cytosolic NADP(+)-dependent isocitrate dehydrogenase in complex NADP | 分子名称: | Isocitrate dehydrogenase [NADP] cytoplasmic, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Xu, X, Zhao, J, Peng, B, Huang, Q, Arnold, E, Ding, J. | 登録日 | 2004-04-08 | 公開日 | 2004-06-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity J.Biol.Chem., 279, 2004
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2AJI
| Crystal structure of the editing domain of E. coli leucyl-tRNA synthetase complexes with isoleucine | 分子名称: | ISOLEUCINE, Leucyl-tRNA synthetase | 著者 | Liu, Y, Liao, J, Zhu, B, Wang, E.D, Ding, J. | 登録日 | 2005-08-02 | 公開日 | 2006-01-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Crystal structures of the editing domain of Escherichia coli leucyl-tRNA synthetase and its complexes with Met and Ile reveal a lock-and-key mechanism for amino acid discrimination Biochem.J., 394, 2006
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7BTD
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8JDN
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyvaleric acid | 分子名称: | (2R)-2-oxidanylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDS
| Crystal structure of mLDHD in complex with Pyruvate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, PYRUVIC ACID, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.636 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDB
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyoctanoic acid | 分子名称: | (2R)-2-oxidanyloctanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDC
| Crystal structure of mLDHD in apo form | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDQ
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisocaproic acid | 分子名称: | (2R)-2-hydroxy-4-methylpentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDT
| Crystal structure of mLDHD in complex with 2-ketobutanoic acid | 分子名称: | 2-KETOBUTYRIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDV
| Crystal structure of mLDHD in complex with 2-ketohexanoic acid | 分子名称: | 2-Ketohexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDD
| Crystal structure of H405A mLDHD in apo form | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, mitochondrial | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDZ
| Crystal structure of mLDHD in complex with 2-keto-3-methylvaleric acid | 分子名称: | (3S)-3-methyl-2-oxopentanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDF
| Crystal structure of H405A mLDHD in complex with D-lactate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDX
| Crystal structure of mLDHD in complex with 2-ketoisovaleric acid | 分子名称: | 3-METHYL-2-OXOBUTANOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDE
| Crystal structure of mLDHD in complex with D-lactate | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, LACTIC ACID, MANGANESE (II) ION, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-13 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.729 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDO
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyhexanoic acid | 分子名称: | (2R)-2-hydroxyhexanoic acid, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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8JDP
| Crystal structure of H405A mLDHD in complex with D-2-hydroxyisovaleric acid | 分子名称: | DEAMINOHYDROXYVALINE, FLAVIN-ADENINE DINUCLEOTIDE, Probable D-lactate dehydrogenase, ... | 著者 | Jin, S, Chen, X, Yang, J, Ding, J. | 登録日 | 2023-05-15 | 公開日 | 2023-10-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Lactate dehydrogenase D is a general dehydrogenase for D-2-hydroxyacids and is associated with D-lactic acidosis. Nat Commun, 14, 2023
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