7WR5

Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+

Summary for 7WR5

• Entry DOI: 10.2210/pdb7wr5/pdb
• Descriptor: OspC3, Calmodulin-1, Caspase-4, ... (4 entities in total)
• Functional Keywords: adp-riboxanase, effector, transferase
• Biological source: Shigella flexneri; More
• Total number of polymer chains: 3
• Total formula weight: 99319.47

Authors

Hou, Y.J.,Zeng, H.,Shao, F.,Ding, J. (deposition date: 2022-01-26, release date: 2023-01-25, Last modification date: 2023-11-29)

• Primary citation: Hou, Y.,Zeng, H.,Li, Z.,Feng, N.,Meng, F.,Xu, Y.,Li, L.,Shao, F.,Ding, J.; Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.; Nat.Struct.Mol.Biol., 30:261-272, 2023; PubMed: 36624349; DOI: 10.1038/s41594-022-00888-3

Experimental method

X-RAY DIFFRACTION (3.1 Å)