7WR5
Crystal structure of OspC3-calmodulin-caspase-4 complex binding with 2'-aF-NAD+
Summary for 7WR5
Entry DOI | 10.2210/pdb7wr5/pdb |
Descriptor | OspC3, Calmodulin-1, Caspase-4, ... (4 entities in total) |
Functional Keywords | adp-riboxanase, effector, transferase |
Biological source | Shigella flexneri More |
Total number of polymer chains | 3 |
Total formula weight | 99319.47 |
Authors | |
Primary citation | Hou, Y.,Zeng, H.,Li, Z.,Feng, N.,Meng, F.,Xu, Y.,Li, L.,Shao, F.,Ding, J. Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis. Nat.Struct.Mol.Biol., 30:261-272, 2023 Cited by PubMed: 36624349DOI: 10.1038/s41594-022-00888-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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