6OGY
| In situ structure of Rotavirus RNA-dependent RNA polymerase at duplex-open state | 分子名称: | DNA/RNA (5'-D(*(GTG))-R(P*GP*C)-3'), Inner capsid protein VP2, RNA (5'-R(P*AP*GP*CP*C)-3'), ... | 著者 | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | 登録日 | 2019-04-03 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
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6OGZ
| In situ structure of Rotavirus RNA-dependent RNA polymerase at transcript-elongated state | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, Inner capsid protein VP2, RNA (5'-R(P*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*AP*UP*A)-3'), ... | 著者 | Ding, K, Chang, T, Shen, W, Roy, P, Zhou, Z.H. | 登録日 | 2019-04-03 | 公開日 | 2019-05-22 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release. Nat Commun, 10, 2019
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6M99
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6BP7
| Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 2 | 分子名称: | Major vault protein | 著者 | Ding, K, Zhang, X, Mrazek, J, Kickhoefer, V.A, Lai, M, Ng, H.L, Yang, O.O, Rome, L.H, Zhou, Z.H. | 登録日 | 2017-11-22 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Solution Structures of Engineered Vault Particles. Structure, 26, 2018
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6BP8
| Recombinant major vault protein [Rattus norvegicus] structure in solution: conformation 1 | 分子名称: | Major vault protein | 著者 | Ding, K, Zhang, X, Mrazek, J, Kickhoefer, V.A, Lai, M, Ng, H.L, Yang, O.O, Rome, L.H, Zhou, Z.H. | 登録日 | 2017-11-22 | 公開日 | 2018-04-04 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Solution Structures of Engineered Vault Particles. Structure, 26, 2018
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2HJQ
| NMR Structure of Bacillus Subtilis Protein YqbF, Northeast Structural Genomics Target SR449 | 分子名称: | Hypothetical protein yqbF | 著者 | Ding, K, Ramelot, T.A, Cort, J.R, Wang, D, Janjua, H, Cunningham, K, Ma, L.-C, Xiao, R, Liu, J, Baran, M, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-06-30 | 公開日 | 2007-06-05 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of Bacillus Subtilis Protein YqbF, Northeast Structural Genomics Target SR449 TO BE PUBLISHED
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2JOV
| NMR Structure of Clostridium Perfringens Protein CPE0013. Northeast Structural Genomics Target CpR31. | 分子名称: | Hypothetical protein CPE0013 | 著者 | Ding, K, Ramelot, T.A, Anklin, C.G, Wang, H, Nwosu, C, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-04-04 | 公開日 | 2007-05-08 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of Clostridium perfringens protein CPE0013. To be Published
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2JRP
| Solution NMR Structure of YfgJ from Salmonella typhimurium Modeled with Two Zn+2 Bound, Northeast Structural Genomics Consortium Target StR86 | 分子名称: | Putative cytoplasmic protein, ZINC ION | 著者 | Ding, K, Ramelot, T.A, Cort, J.R, Wang, H, Nwosu, C, Cunningham, K, Owens, L, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-06-28 | 公開日 | 2007-07-10 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of YfgJ from Salmonella typhimurium Modeled with Two Zn+2 Bound. To be Published
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2JOE
| NMR Structure of E. Coli YehR Protein. Northeast Structural Genomics Target ER538. | 分子名称: | Hypothetical lipoprotein yehR | 著者 | Ding, K, Ramelot, T.A, Cort, J.R, Chen, C.X, Jiang, M, Cunningham, K, Ma, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-03-08 | 公開日 | 2007-04-10 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure of E. Coli YehR Protein To be Published
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2JUZ
| Solution NMR structure of HI0947 from Haemophilus influenzae, Northeast Structural Genomics Consortium Target IR123 | 分子名称: | UPF0352 protein HI0840 | 著者 | Ding, K, Ramelot, T.A, Cort, J.R, Wang, D, Nwosu, C, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-09-09 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of HI0947 from Haemophilus influenzae. To be Published
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2JZ8
| Solution NMR structure of BH09830 from Bartonella henselae modeled with one Zn+2 bound. Northeast Structural Genomics Consortium target BnR55 | 分子名称: | Uncharacterized protein BH09830, ZINC ION | 著者 | Ding, K, Cort, J.R, Wang, D, Janjua, H, Owens, L, Xiao, R, Liu, J, Baran, M.C, Swapna, G.V.T, Acton, T.B, Rost, B, Montelione, G.T, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2007-12-30 | 公開日 | 2008-01-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of BH09830 from Bartonella henselae modeled with one Zn+2 bound. To be Published
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5V56
| 2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN MONONUCLEOTIDE, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, ... | 著者 | Zhang, X, Zhao, F, Wu, Y, Yang, J, Han, G.W, Zhao, S, Ishchenko, A, Ye, L, Lin, X, Ding, K, Dharmarajan, V, Griffin, P.R, Gati, C, Nelson, G, Hunter, M.S, Hanson, M.A, Cherezov, V, Stevens, R.C, Tan, W, Tao, H, Xu, F. | 登録日 | 2017-03-13 | 公開日 | 2017-05-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand. Nat Commun, 8, 2017
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8XN7
| Crystal structure of HPK1 kinase domain T165E,S171E phosphomimetic mutant in complex with compound 9f | 分子名称: | 5-amino-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-8-(2-(trifluoromethyl)benzyl)pyrido[2,3-d]pyrimidin-7(8H)-one, Mitogen-activated protein kinase kinase kinase kinase 1 | 著者 | Huang, W.X, Liu, R, Ding, K. | 登録日 | 2023-12-29 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of 5-aminopyrido[2,3-d]pyrimidin-7(8H)-one derivatives as new hematopoietic progenitor kinase 1 (HPK1) inhibitors. Eur.J.Med.Chem., 269, 2024
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6PO2
| In situ structure of BTV RNA-dependent RNA polymerase in BTV core | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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6PNS
| In situ structure of BTV RNA-dependent RNA polymerase in BTV virion | 分子名称: | Inner core structural protein VP3, RNA-directed RNA polymerase | 著者 | He, Y, Shivakoti, S, Ding, K, Cui, Y, Roy, P, Zhou, Z.H. | 登録日 | 2019-07-03 | 公開日 | 2019-08-07 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | In situ structures of RNA-dependent RNA polymerase inside bluetongue virus before and after uncoating. Proc.Natl.Acad.Sci.USA, 116, 2019
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7RPK
| Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog | 分子名称: | (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | 登録日 | 2021-08-03 | 公開日 | 2021-10-27 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599, 2021
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7RPJ
| Cryo-EM structure of murine Dispatched NNN mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Protein dispatched homolog 1 | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | 登録日 | 2021-08-03 | 公開日 | 2021-10-27 | 最終更新日 | 2021-11-24 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599, 2021
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7RPH
| Cryo-EM structure of murine Dispatched 'R' conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | 登録日 | 2021-08-03 | 公開日 | 2021-10-27 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599, 2021
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7RPI
| Cryo-EM structure of murine Dispatched 'T' conformation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, Lauryl Maltose Neopentyl Glycol, ... | 著者 | Asarnow, D, Wang, Q, Ding, K, Cheng, Y, Beachy, P.A. | 登録日 | 2021-08-03 | 公開日 | 2021-10-27 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Dispatched uses Na + flux to power release of lipid-modified Hedgehog. Nature, 599, 2021
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6PYT
| CryoEM Structure of Pyocin R2 - precontracted - trunk | 分子名称: | Pyocin sheath PA0622, Pyocin tube PA0623 | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-07-30 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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6U5B
| CryoEM Structure of Pyocin R2 - precontracted - baseplate | 分子名称: | Glue PA0627, Ripcord PA0626, Sheath Initiator PA0617, ... | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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6U5H
| CryoEM Structure of Pyocin R2 - precontracted - hub | 分子名称: | Probable bacteriophage protein Pyocin R2 | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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6U5K
| CryoEM Structure of Pyocin R2 - postcontracted - baseplate | 分子名称: | Glue PA0627, Sheath Initiator PA0617, Sheath PA0622, ... | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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6U5F
| CryoEM Structure of Pyocin R2 - precontracted - collar | 分子名称: | Collar PA0615, Sheath PA0622, Tube PA0623 | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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6U5J
| CryoEM Structure of Pyocin R2 - postcontracted - collar | 分子名称: | Collar PA0615, Sheath PA0622 | 著者 | Ge, P, Avaylon, J, Scholl, D, Shneider, M.M, Browning, C, Buth, S.A, Plattner, M, Ding, K, Leiman, P.G, Miller, J.F, Zhou, Z.H. | 登録日 | 2019-08-27 | 公開日 | 2020-04-15 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Action of a minimal contractile bactericidal nanomachine. Nature, 580, 2020
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