2I35
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![BU of 2i35 by Molmil](/molmil-images/mine/2i35) | Crystal structure of rhombohedral crystal form of ground-state rhodopsin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, RETINAL, ... | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | 登録日 | 2006-08-17 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc.Natl.Acad.Sci.Usa, 103, 2006
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5V10
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![BU of 5v10 by Molmil](/molmil-images/mine/5v10) | Crystal structure of the putative tol-pal system-associated acyl-CoA thioesterase from Pseudomonas aeruginosa PAO1 | 分子名称: | CHLORIDE ION, Uncharacterized protein | 著者 | Borek, D, Wawrzak, Z, Grimshaw, S, Sandoval, J, Evdokimova, E, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2017-02-28 | 公開日 | 2017-03-22 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of the putative tol-pal system-associated acyl-CoA thioesterase from Pseudomonas aeruginosa PAO1 To Be Published
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7ZYC
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2I68
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![BU of 2i68 by Molmil](/molmil-images/mine/2i68) | Cryo-EM based theoretical model structure of transmembrane domain of the multidrug-resistance antiporter from E. coli EmrE | 分子名称: | Protein emrE | 著者 | Fleishman, S.J, Harrington, S.E, Enosh, A, Halperin, D, Tate, C.G, Ben-Tal, N. | 登録日 | 2006-08-28 | 公開日 | 2006-10-03 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON CRYSTALLOGRAPHY (7.5 Å) | 主引用文献 | Quasi-symmetry in the Cryo-EM Structure of EmrE Provides the Key to Modeling its Transmembrane Domain J.Mol.Biol., 364, 2006
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3DKI
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7ZYB
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3DO9
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![BU of 3do9 by Molmil](/molmil-images/mine/3do9) | Crystal structure of protein ba1542 from bacillus anthracis str.ames | 分子名称: | UPF0302 protein BA_1542/GBAA1542/BAS1430 | 著者 | Patskovsky, Y, Ozyurt, S, Freeman, J, Iizuka, M, Maletic, M, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2008-07-03 | 公開日 | 2008-09-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structure of Protein Ba1542 from Bacillus Anthracis Str.Ames. To be Published
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7ZY3
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![BU of 7zy3 by Molmil](/molmil-images/mine/7zy3) | Room temperature structure of Archaerhodopsin-3 obtained 110 ns after photoexcitation | 分子名称: | Archaerhodopsin-3, CALCIUM ION, CHLORIDE ION, ... | 著者 | Kwan, T.O.C, Judge, P.J, Moraes, I, Watts, A, Axford, D, Bada Juarez, J.F. | 登録日 | 2022-05-23 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | A versatile approach to high-density microcrystals in lipidic cubic phase for room-temperature serial crystallography. J.Appl.Crystallogr., 56, 2023
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8A4V
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![BU of 8a4v by Molmil](/molmil-images/mine/8a4v) | Crystal structure of human cathepsin L with covalently bound E-64 | 分子名称: | Cathepsin L, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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3DRJ
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![BU of 3drj by Molmil](/molmil-images/mine/3drj) | Crystal structure of Lactococcal OppA co-crystallized with pTH-related peptide in an open conformation | 分子名称: | Oligopeptide-binding protein oppA, pTH-related peptide | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA Embo J., 28, 2009
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2HYY
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![BU of 2hyy by Molmil](/molmil-images/mine/2hyy) | Human Abl kinase domain in complex with imatinib (STI571, Glivec) | 分子名称: | 4-(4-METHYL-PIPERAZIN-1-YLMETHYL)-N-[4-METHYL-3-(4-PYRIDIN-3-YL-PYRIMIDIN-2-YLAMINO)-PHENYL]-BENZAMIDE, Proto-oncogene tyrosine-protein kinase ABL1 | 著者 | Cowan-Jacob, S.W, Fendrich, G, Liebetanz, J, Fabbro, D, Manley, P. | 登録日 | 2006-08-08 | 公開日 | 2007-01-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukaemia. ACTA CRYSTALLOGR.,SECT.D, 63, 2007
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2HZK
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![BU of 2hzk by Molmil](/molmil-images/mine/2hzk) | Crystal structures of a sodium-alpha-keto acid binding subunit from a TRAP transporter in its open form | 分子名称: | GLYCEROL, TRAP-T family sorbitol/mannitol transporter, periplasmic binding protein, ... | 著者 | Gonin, S, Arnoux, P, Pierru, B, Alonso, B, Sabaty, M, Pignol, D. | 登録日 | 2006-08-09 | 公開日 | 2007-04-03 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of an Extracytoplasmic Solute Receptor from a TRAP transporter in its open and closed forms reveal a helix-swapped dimer requiring a cation for alpha-keto acid binding. Bmc Struct.Biol., 7, 2007
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2I0T
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3DRH
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![BU of 3drh by Molmil](/molmil-images/mine/3drh) | Crystal structure of Lactococcal OppA co-crystallized with Leu-enkephalin in an open conformation | 分子名称: | Oligopeptide-binding protein oppA, peptide AAAAAA | 著者 | Berntsson, R.P.-A, Doeven, M.K, Duurkens, R.H, Sengupta, D, Marrink, S.-J, Thunnissen, A.-M, Poolman, B, Slotboom, D.-J. | 登録日 | 2008-07-11 | 公開日 | 2009-03-31 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The structural basis for peptide selection by the transport receptor OppA Embo J., 28, 2009
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5V8X
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8A4W
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![BU of 8a4w by Molmil](/molmil-images/mine/8a4w) | Crystal structure of human cathepsin L with covalently bound Cathepsin L inhibitor IV | 分子名称: | 1,2-ETHANEDIOL, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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5UTL
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8A4X
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![BU of 8a4x by Molmil](/molmil-images/mine/8a4x) | Crystal structure of human Cathepsin L with covalently bound Calpain inhibitor III | 分子名称: | (phenylmethyl) N-[(2S)-3-methyl-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]butan-2-yl]carbamate, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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8A4U
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![BU of 8a4u by Molmil](/molmil-images/mine/8a4u) | Crystal structure of human cathepsin L with CAA0225 | 分子名称: | (2S,3S)-N3-[2-(4-hydroxyphenyl)ethyl]-N2-[(2S)-1-oxidanylidene-3-phenyl-1-[(phenylmethyl)amino]propan-2-yl]oxirane-2,3-dicarboxamide, 1,2-ETHANEDIOL, Cathepsin L, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-13 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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3ZPZ
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![BU of 3zpz by Molmil](/molmil-images/mine/3zpz) | Visualizing GroEL-ES in the Act of Encapsulating a Non-Native Substrate Protein | 分子名称: | 10 KDA CHAPERONIN, 60 KDA CHAPERONIN, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Chen, D.-H, Madan, D, Weaver, J, Lin, Z, Schroder, G.F, Chiu, W, Rye, H.S. | 登録日 | 2013-03-04 | 公開日 | 2013-06-19 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | 主引用文献 | Visualizing Groel/Es in the Act of Encapsulating a Folding Protein Cell(Cambridge,Mass.), 153, 2013
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5UKH
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![BU of 5ukh by Molmil](/molmil-images/mine/5ukh) | Structure of TelC from Streptococcus intermedius B196 | 分子名称: | CALCIUM ION, Uncharacterized protein | 著者 | Whitney, J.C, Ching, M.Q, Bryant, D, Mougous, J.D. | 登録日 | 2017-01-22 | 公開日 | 2017-07-26 | 最終更新日 | 2019-12-11 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | A broadly distributed toxin family mediates contact-dependent antagonism between gram-positive bacteria. Elife, 6, 2017
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2I36
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![BU of 2i36 by Molmil](/molmil-images/mine/2i36) | Crystal structure of trigonal crystal form of ground-state rhodopsin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITIC ACID, Rhodopsin, ... | 著者 | Stenkamp, R.E, Le Trong, I, Lodowski, D.T, Salom, D, Palczewski, K. | 登録日 | 2006-08-17 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (4.1 Å) | 主引用文献 | Crystal structure of a photoactivated deprotonated intermediate of rhodopsin. Proc.Natl.Acad.Sci.Usa, 103, 2006
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3X1H
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![BU of 3x1h by Molmil](/molmil-images/mine/3x1h) | hPPARgamma Ligand binding domain in complex with 5-oxo-tricosahexaenoic acid | 分子名称: | (7E,11Z,14Z,17Z,20Z)-5-oxotricosa-7,11,14,17,20-pentaenoic acid, Peroxisome proliferator-activated receptor gamma | 著者 | Egawa, D, Itoh, T, Yamamoto, K. | 登録日 | 2014-11-18 | 公開日 | 2015-04-08 | 最終更新日 | 2022-08-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids. Bioconjug.Chem., 26, 2015
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8A5B
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![BU of 8a5b by Molmil](/molmil-images/mine/8a5b) | Crystal structure of human cathepsin L in complex with covalently bound MG-101 | 分子名称: | Calpain Inhibitor I, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Falke, S, Lieske, J, Guenther, S, Reinke, P.Y.A, Ewert, W, Loboda, J, Karnicar, K, Usenik, A, Lindic, N, Sekirnik, A, Chapman, H.N, Hinrichs, W, Turk, D, Meents, A. | 登録日 | 2022-06-14 | 公開日 | 2023-07-05 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Elucidation and Antiviral Activity of Covalent Cathepsin L Inhibitors. J.Med.Chem., 67, 2024
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3ZOS
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![BU of 3zos by Molmil](/molmil-images/mine/3zos) | Structure of the DDR1 kinase domain in complex with ponatinib | 分子名称: | 1,2-ETHANEDIOL, 3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide, EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 | 著者 | Canning, P, Elkins, J.M, Goubin, S, Mahajan, P, Bradley, A, Coutandin, D, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | 登録日 | 2013-02-22 | 公開日 | 2013-05-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural Mechanisms Determining Inhibition of the Collagen Receptor Ddr1 by Selective and Multi-Targeted Type II Kinase Inhibitors J.Mol.Biol., 426, 2014
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