3L4Q
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![BU of 3l4q by Molmil](/molmil-images/mine/3l4q) | Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein | 分子名称: | GLYCEROL, Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta | 著者 | Hale, B.G, Kerry, P.S, Jackson, D, Precious, B.L, Gray, A, Killip, M.J, Randall, R.E, Russell, R.J. | 登録日 | 2009-12-21 | 公開日 | 2010-02-02 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein Proc.Natl.Acad.Sci.USA, 107, 2010
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3KFT
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![BU of 3kft by Molmil](/molmil-images/mine/3kft) | Crystal structure of Pentaerythritol Tetranitrate Reductase complex with 1,4,5,6-tetrahydro NADH | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Pentaerythritol tetranitrate reductase | 著者 | Pudney, C.R, Levy, C.W, Leys, D, Scrutton, N.S. | 登録日 | 2009-10-28 | 公開日 | 2010-02-02 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Evidence to support the hypothesis that promoting vibrations enhance the rate of an enzyme catalyzed H-tunneling reaction. J.Am.Chem.Soc., 131, 2009
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3KJM
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3KLA
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![BU of 3kla by Molmil](/molmil-images/mine/3kla) | Ca2+ release from the endoplasmic reticulum of NY-ESO-1 specific T cells is modulated by the affinity of T cell receptor and by the use of the CD8 co-receptor | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Chen, J.L, Morgan, A.J, Stewart-Jones, G, Shepherd, D, Bossi, G, Wooldridge, L. | 登録日 | 2009-11-07 | 公開日 | 2010-02-16 | 最終更新日 | 2021-10-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Ca2+ Release from the Endoplasmic Reticulum of NY-ESO-1-Specific T Cells Is Modulated by the Affinity of TCR and by the Use of the CD8 Coreceptor. J.Immunol., 184, 2010
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3KOY
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![BU of 3koy by Molmil](/molmil-images/mine/3koy) | Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic) | 分子名称: | (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
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3KUC
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![BU of 3kuc by Molmil](/molmil-images/mine/3kuc) | Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R) | 分子名称: | CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Filchtinski, D, Sharabi, O, Rueppel, A, Vetter, I.R, Herrmann, C, Shifman, J.M. | 登録日 | 2009-11-27 | 公開日 | 2010-03-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. J.Mol.Biol., 399, 2010
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3KP8
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![BU of 3kp8 by Molmil](/molmil-images/mine/3kp8) | The thioredoxin-like domain of a VKOR homolog from Synechococcus sp. | 分子名称: | VKORC1/thioredoxin domain protein | 著者 | Li, W, Schulman, S, Dutton, R.J, Boyd, D, Beckwith, J, Rapoport, T.A. | 登録日 | 2009-11-15 | 公開日 | 2010-03-02 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structure of a bacterial homologue of vitamin K epoxide reductase. Nature, 463, 2010
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3KPE
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![BU of 3kpe by Molmil](/molmil-images/mine/3kpe) | Solution structure of the respiratory syncytial virus (RSV)six-helix bundle complexed with TMC353121, a small-moleucule inhibitor of RSV | 分子名称: | 2-[[6-[[[2-(3-hydroxypropyl)-5-methylphenyl]amino]methyl]-2-[[3-(4-morpholinyl)propyl]amino]-1H-benzimidazol-1-yl]methyl]-6-methyl-3-pyridinol, Fusion glycoprotein F0, TETRAETHYLENE GLYCOL | 著者 | Roymans, D, De Bondt, H, Arnoult, E, Cummings, M.D, Van Vlijmen, H, Andries, K. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KVU
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![BU of 3kvu by Molmil](/molmil-images/mine/3kvu) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA FlK - T42S mutant in complex with Acetyl-CoA | 分子名称: | ACETYL COENZYME *A, Fluoroacetyl-CoA thioesterase FlK | 著者 | Dias, M.V.B, Huang, F, Chirgadze, D.Y, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | 登録日 | 2009-11-30 | 公開日 | 2010-04-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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3KW6
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![BU of 3kw6 by Molmil](/molmil-images/mine/3kw6) | Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A | 分子名称: | 26S protease regulatory subunit 8 | 著者 | Seetharaman, J, Su, M, Wang, D, Janjua, H, Cunningham, K, Owens, L, Xiao, R, Liu, J, Baran, M.C, Acton, T.B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-11-30 | 公開日 | 2009-12-22 | 最終更新日 | 2018-01-24 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A To be Published
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3KPL
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![BU of 3kpl by Molmil](/molmil-images/mine/3kpl) | Crystal Structure of HLA B*4402 in complex with EEYLQAFTY a self peptide from the ABCD3 protein | 分子名称: | Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3KPS
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![BU of 3kps by Molmil](/molmil-images/mine/3kps) | Crystal Structure of the LC13 TCR in complex with HLA B*4405 bound to EEYLQAFTY a self peptide from the ABCD3 protein | 分子名称: | Beta-2-microglobulin, EEYLQAFTY, self peptide from the ATP binding cassette protein ABCD3, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3KRD
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3KFQ
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3KPC
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![BU of 3kpc by Molmil](/molmil-images/mine/3kpc) | Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine | 分子名称: | 5'-DEOXY-5'-METHYLTHIOADENOSINE, S-ADENOSYLMETHIONINE, Uncharacterized protein MJ0100 | 著者 | Lucas, M, Oyenarte, I, Garcia, I.G, Arribas, E.A, Encinar, J.A, Kortazar, D, Fernandez, J.A, Mato, J.M, Martinez-Chantar, M.L, Martinez-Cruz, L.A. | 登録日 | 2009-11-16 | 公開日 | 2010-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair. J.Mol.Biol., 396, 2010
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3KZK
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![BU of 3kzk by Molmil](/molmil-images/mine/3kzk) | Crystal structure of acetylornithine transcarbamylase complexed with acetylcitrulline | 分子名称: | (S)-2-ACETAMIDO-5-UREIDOPENTANOIC ACID, N-acetylornithine carbamoyltransferase, SULFATE ION | 著者 | Shi, D, Yu, X, Allewell, N.M, Tuchman, M. | 登録日 | 2009-12-08 | 公開日 | 2010-03-31 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris: a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria. J.Biol.Chem., 280, 2005
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3KO0
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![BU of 3ko0 by Molmil](/molmil-images/mine/3ko0) | Structure of the tfp-ca2+-bound activated form of the s100a4 Metastasis factor | 分子名称: | 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, Protein S100-A4 | 著者 | Malashkevich, V.N, Dulyaninova, N.G, Knight, D, Almo, S.C, Bresnick, A.R. | 登録日 | 2009-11-12 | 公開日 | 2010-05-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KPP
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![BU of 3kpp by Molmil](/molmil-images/mine/3kpp) | Crystal Structure of HLA B*4405 in complex with EEYLQAFTY a self peptide from the ABCD3 protein | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, EEYLQAFTY, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3KPZ
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![BU of 3kpz by Molmil](/molmil-images/mine/3kpz) | Crystal structure of a novel vitamin D3 analogue, ZK203278 showing dissociated profile | 分子名称: | (1R,3S,5Z)-5-[(2E)-2-{(1R,3aS,7aR)-1-[(1R,5S)-5-hydroxy-1-methyl-5-(1,3-thiazol-2-yl)pentyl]-7a-methyloctahydro-4H-inden-4-ylidene}ethylidene]-4-methylidenecyclohexane-1,3-diol, Vitamin D3 receptor | 著者 | Rochel, N, Moras, D. | 登録日 | 2009-11-17 | 公開日 | 2011-10-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of a vitamin D3 analog, ZK203278, showing dissociated profile. Anticancer Res., 32, 2012
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3KPO
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![BU of 3kpo by Molmil](/molmil-images/mine/3kpo) | Crystal Structure of HLA B*4403 in complex with EEYLKAWTF, a mimotope | 分子名称: | Beta-2-microglobulin, EEYLKAWTF, mimotope peptide, ... | 著者 | Macdonald, W.A, Chen, Z, Gras, S, Archbold, J.K, Tynan, F.E, Clements, C.S, Bharadwaj, M, Kjer-Nielsen, L, Saunders, P.M, Wilce, M.C, Crawford, F, Stadinsky, B, Jackson, D, Brooks, A.G, Purcell, A.W, Kappler, J.W, Burrows, S.R, Rossjohn, J, McCluskey, J. | 登録日 | 2009-11-16 | 公開日 | 2009-12-22 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | T cell allorecognition via molecular mimicry. Immunity, 31, 2009
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3KUV
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![BU of 3kuv by Molmil](/molmil-images/mine/3kuv) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK - T42S mutant in complex with acetate. | 分子名称: | ACETATE ION, Fluoroacetyl coenzyme A thioesterase | 著者 | Dias, M.V.B, Huang, F, Chirgadze, D.Y, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | 登録日 | 2009-11-27 | 公開日 | 2010-04-21 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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3L0N
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![BU of 3l0n by Molmil](/molmil-images/mine/3l0n) | Human orotidyl-5'-monophosphate decarboxylase in complex with 6-mercapto-UMP | 分子名称: | 6-sulfanyluridine-5'-phosphate, Uridine 5'-monophosphate synthase | 著者 | Heinrich, D, Wittmann, J, Diederichsen, U, Rudolph, M. | 登録日 | 2009-12-10 | 公開日 | 2010-01-26 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Lys314 is a nucleophile in non-classical reactions of orotidine-5'-monophosphate decarboxylase Chemistry, 15, 2009
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3KX8
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![BU of 3kx8 by Molmil](/molmil-images/mine/3kx8) | Structural basis of the activity and substrate specificity of the fluoroacetyl-CoA thioesterase FlK | 分子名称: | fluoroacetyl-CoA thioesterase | 著者 | Chirgadze, D.Y, Dias, M.V.B, Huang, F, Tosin, M, Spiteller, D, Valentine, E.F, Leadlay, P.F, Spencer, J.B, Blundell, T.L. | 登録日 | 2009-12-02 | 公開日 | 2010-04-28 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis for the activity and substrate specificity of fluoroacetyl-CoA thioesterase FlK. J.Biol.Chem., 285, 2010
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3KOZ
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![BU of 3koz by Molmil](/molmil-images/mine/3koz) | Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Anaerobic) | 分子名称: | (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ... | 著者 | Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D. | 登録日 | 2009-11-14 | 公開日 | 2010-01-26 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase. J.Biol.Chem., 285, 2010
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3KPB
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![BU of 3kpb by Molmil](/molmil-images/mine/3kpb) | Crystal Structure of the CBS domain pair of protein MJ0100 in complex with 5 -methylthioadenosine and S-adenosyl-L-methionine. | 分子名称: | GLYCEROL, S-ADENOSYLMETHIONINE, Uncharacterized protein MJ0100 | 著者 | Lucas, M, Oyenarte, I, Garcia, I.G, Arribas, E.A, Encinar, J.A, Kortazar, D, Fernandez, J.A, Mato, J.M, Martinez-Cruz, L.A. | 登録日 | 2009-11-16 | 公開日 | 2010-01-12 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Binding of S-Methyl-5'-Thioadenosine and S-Adenosyl-l-Methionine to Protein MJ0100 Triggers an Open-to-Closed Conformational Change in Its CBS Motif Pair. J.Mol.Biol., 396, 2010
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