3KUC
Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)
Summary for 3KUC
Entry DOI | 10.2210/pdb3kuc/pdb |
Related | 3KUD |
Descriptor | Ras-related protein Rap-1A, RAF proto-oncogene serine/threonine-protein kinase, GUANOSINE-5'-DIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | ras-effector complex, gtp-binding, nucleotide-binding, proto-oncogene, transferase, gtp binding protein-transferase complex, gtp binding protein/transferase |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Lipid-anchor : P62834 Cytoplasm: P04049 |
Total number of polymer chains | 2 |
Total formula weight | 28854.09 |
Authors | Filchtinski, D.,Sharabi, O.,Rueppel, A.,Vetter, I.R.,Herrmann, C.,Shifman, J.M. (deposition date: 2009-11-27, release date: 2010-03-23, Last modification date: 2023-09-06) |
Primary citation | Filchtinski, D.,Sharabi, O.,Ruppel, A.,Vetter, I.R.,Herrmann, C.,Shifman, J.M. What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. J.Mol.Biol., 399:422-435, 2010 Cited by PubMed: 20361980DOI: 10.1016/j.jmb.2010.03.046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.92 Å) |
Structure validation
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