3KUC
Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein Rap-1A | polymer | 167 | 19041.5 | 1 | UniProt (P62834) Pfam (PF00071) | Homo sapiens (human) | GTP-binding protein smg-p21A, Ras-related protein Krev-1, C21KG, G-22K |
| 2 | B (B) | RAF proto-oncogene serine/threonine-protein kinase | polymer | 81 | 9305.0 | 1 | UniProt (P04049) Pfam (PF02196) | Homo sapiens (human) | C-RAF, cRaf, Raf-1 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 1 - 167 (UniProt: P62834)
B: 51 - 131 (UniProt: P04049)
| PDB | External Database | Details |
|---|---|---|
| Asp 30 | Glu 30 | engineered mutation |
| Glu 31 | Lys 31 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 71 | Asn 71 | engineered mutation |
| Lys 85 | Ala 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28346.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.6 | |
| All* | Total formula weight | 28854.1 |
