3KUC
Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Ras-related protein Rap-1A | polymer | 167 | 19041.5 | 1 | UniProt (P62834) Pfam (PF00071) | Homo sapiens (human) | GTP-binding protein smg-p21A, Ras-related protein Krev-1, C21KG, G-22K |
| 2 | B (B) | RAF proto-oncogene serine/threonine-protein kinase | polymer | 81 | 9305.0 | 1 | UniProt (P04049) Pfam (PF02196) | Homo sapiens (human) | C-RAF, cRaf, Raf-1 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 5 | E (B) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 1 - 167 (UniProt: P62834)
B: 51 - 131 (UniProt: P04049)
| PDB | External Database | Details |
|---|---|---|
| Asp 30 | Glu 30 | engineered mutation |
| Glu 31 | Lys 31 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 71 | Asn 71 | engineered mutation |
| Lys 85 | Ala 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28346.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 507.6 | |
| All* | Total formula weight | 28854.1 |
