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3KUC

Complex of Rap1A(E30D/K31E)GDP with RafRBD(A85K/N71R)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ARas-related protein Rap-1Apolymer16719041.51UniProt (P62834)
Pfam (PF00071)
In PDB
Homo sapiens (human)GTP-binding protein smg-p21A, Ras-related protein Krev-1, C21KG, G-22K
2BRAF proto-oncogene serine/threonine-protein kinasepolymer819305.01UniProt (P04049)
Pfam (PF02196)
In PDB
Homo sapiens (human)C-RAF, cRaf, Raf-1
3AGUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
4AMAGNESIUM IONnon-polymer24.31Chemie (MG)
5BCALCIUM IONnon-polymer40.11Chemie (CA)
6waterwater18.0181Chemie (HOH)
Sequence modifications
A: 1 - 167 (UniProt: P62834)
PDBExternal DatabaseDetails
Asp 30Glu 30engineered mutation
Glu 31Lys 31engineered mutation
B: 51 - 131 (UniProt: P04049)
PDBExternal DatabaseDetails
Arg 71Asn 71engineered mutation
Lys 85Ala 85engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28346.5
Non-Polymers*Number of molecules3
Total formula weight507.6
All*Total formula weight28854.1
*Water molecules are not included.

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PDB entries from 2024-05-01

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