3KUD

Complex of Ras-GDP with RafRBD(A85K)

Summary for 3KUD

• Entry DOI: 10.2210/pdb3kud/pdb
• Related: 3KUC
• Descriptor: GTPase HRas, RAF proto-oncogene serine/threonine-protein kinase, GUANOSINE-5'-DIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: ras-effector complex, gtp-binding, nucleotide-binding, proto-oncogene, transferase, gtp binding protein-transferase complex, gtp binding protein/transferase
• Biological source: Homo sapiens (human); More
• Cellular location: Cell membrane. Isoform 2: Nucleus: P01112; Cytoplasm: P04049
• Total number of polymer chains: 2
• Total formula weight: 28604.56

Authors

Filchtinski, D.,Sharabi, O.,Rueppel, A.,Vetter, I.R.,Herrmann, C.,Shifman, J.M. (deposition date: 2009-11-27, release date: 2010-03-23, Last modification date: 2023-09-06)

• Primary citation: Filchtinski, D.,Sharabi, O.,Ruppel, A.,Vetter, I.R.,Herrmann, C.,Shifman, J.M.; What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf.; J.Mol.Biol., 399:422-435, 2010; PubMed: 20361980; DOI: 10.1016/j.jmb.2010.03.046

Experimental method

X-RAY DIFFRACTION (2.15 Å)