3L4Q

Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein

Summary for 3L4Q

Entry DOI	10.2210/pdb3l4q/pdb
Descriptor	Non-structural protein 1, Phosphatidylinositol 3-kinase regulatory subunit beta, GLYCEROL, ... (4 entities in total)
Functional Keywords	pi3k, phosphoinositide-3-kinase, influenza virus, ns1, kinase, viral protein-protein binding complex, viral protein/protein binding
Biological source	Influenza A virus More
Cellular location	Host nucleus: P03496
Total number of polymer chains	4
Total formula weight	78363.00
Authors	Hale, B.G.,Kerry, P.S.,Jackson, D.,Precious, B.L.,Gray, A.,Killip, M.J.,Randall, R.E.,Russell, R.J. (deposition date: 2009-12-21, release date: 2010-02-02, Last modification date: 2023-11-01)
Primary citation	Hale, B.G.,Kerry, P.S.,Jackson, D.,Precious, B.L.,Gray, A.,Killip, M.J.,Randall, R.E.,Russell, R.J. Structural insights into phosphoinositide 3-kinase activation by the influenza A virus NS1 protein Proc.Natl.Acad.Sci.USA, 107:1954-1959, 2010 Cited by PubMed: 20133840 DOI: 10.1073/pnas.0910715107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation