2VWN
| Aminopyrrolidine Factor Xa inhibitor | Descriptor: | 5-Chloro-thiophene-2-carboxylic acid ((3S,4S)-1-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenylcarbamoyl]-methyl}-4-hydroxy-pyrrolidin-3-yl)-amide, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | Authors: | Groebke-Zbinden, K, Banner, D.W, Benz, J.M, Blasco, F, Decoret, G, Himber, J, Kuhn, B, Panday, N, Ricklin, F, Risch, P, Schlatter, D, Stahl, M, Unger, R, Haap, W. | Deposit date: | 2008-06-26 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Design of Novel Aminopyrrolidine Factor Xa Inhibitors from a Screening Hit. Eur.J.Med.Chem., 44, 2009
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1K91
| Solution Structure of Calreticulin P-domain subdomain (residues 221-256) | Descriptor: | CALRETICULIN | Authors: | Ellgaard, L, Bettendorff, P, Braun, D, Herrmann, T, Fiorito, F, Guntert, P, Helenius, A, Wuthrich, K. | Deposit date: | 2001-10-26 | Release date: | 2002-10-12 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | NMR Structures of 36 and 73-residue Fragments of the Calreticulin P-domain J.Mol.Biol., 322, 2002
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1K9E
| Crystal structure of a mutated family-67 alpha-D-glucuronidase (E285N) from Bacillus stearothermophilus T-6, complexed with 4-O-methyl-glucuronic acid | Descriptor: | 4-O-methyl-alpha-D-glucopyranuronic acid, GLYCEROL, alpha-D-glucuronidase | Authors: | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | Deposit date: | 2001-10-29 | Release date: | 2002-10-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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8J2Y
| Acidimicrobiaceae bacterium photocobilins protein, dark state | Descriptor: | 5'-DEOXYADENOSINE, COBALAMIN, DI(HYDROXYETHYL)ETHER, ... | Authors: | Zhang, S, Poddar, H, Levy, W.C, Leys, D. | Deposit date: | 2023-04-15 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Photocobilins integrate B12 and bilin photochemistry for enzyme control. Nat Commun, 15, 2024
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2IGC
| Structure of Spin labeled T4 Lysozyme Mutant T115R1A | Descriptor: | Lysozyme, S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate | Authors: | Guo, Z, Cascio, D, Hideg, K, Hubbell, W.L. | Deposit date: | 2006-09-22 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural determinants of nitroxide motion in spin-labeled proteins: Tertiary contact and solvent-inaccessible sites in helix G of T4 lysozyme. Protein Sci., 16, 2007
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1KB5
| MURINE T-CELL RECEPTOR VARIABLE DOMAIN/FAB COMPLEX | Descriptor: | ANTIBODY DESIRE-1, KB5-C20 T-CELL ANTIGEN RECEPTOR | Authors: | Housset, D, Mazza, G, Gregoire, C, Piras, C, Malissen, B, Fontecilla-Camps, J.C. | Deposit date: | 1997-04-06 | Release date: | 1998-04-08 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The three-dimensional structure of a T-cell antigen receptor V alpha V beta heterodimer reveals a novel arrangement of the V beta domain. EMBO J., 16, 1997
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8J2X
| Saccharothrix syringae photocobilins protein, light state | Descriptor: | BILIVERDINE IX ALPHA, COBALAMIN, Cobalamin-binding protein, ... | Authors: | Zhang, S, Poddar, H, Levy, C, Leys, D. | Deposit date: | 2023-04-15 | Release date: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Photocobilins integrate B12 and bilin photochemistry for enzyme control. Nat Commun, 15, 2024
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2IUV
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2ITJ
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1K93
| Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin | Descriptor: | CALCIUM ION, CALMODULIN, CALMODULIN-SENSITIVE ADENYLATE CYCLASE, ... | Authors: | Drum, C.L, Yan, S.-Z, Bard, J, Shen, Y.-Q, Lu, D, Soelaiman, S, Grabarek, Z, Bohm, A, Tang, W.-J. | Deposit date: | 2001-10-26 | Release date: | 2002-01-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin. Nature, 415, 2002
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2IL5
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2J74
| Structure of Beta-1,4-Galactanase | Descriptor: | CALCIUM ION, YVFO, beta-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | Authors: | Le Nours, J, De Maria, L, Welner, D, Jorgensen, C.T, Christensen, L.L.H, Larsen, S, Lo Leggio, L. | Deposit date: | 2006-10-06 | Release date: | 2007-12-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Investigating the Binding of Beta-1,4-Galactan to Bacillus Licheniformis Beta-1,4-Galactanase by Crystallography and Computational Modeling. Proteins, 75, 2009
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2IYK
| Crystal structure of the UPF2-interacting domain of nonsense mediated mRNA decay factor UPF1 | Descriptor: | REGULATOR OF NONSENSE TRANSCRIPTS 1, ZINC ION | Authors: | Kadlec, J, Guilligay, D, Ravelli, R.B, Cusack, S. | Deposit date: | 2006-07-18 | Release date: | 2006-08-30 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Crystal Structure of the Upf2-Interacting Domain of Nonsense-Mediated Mrna Decay Factor Upf1. RNA, 12, 2006
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2J8L
| FXI Apple 4 domain loop-out conformation | Descriptor: | COAGULATION FACTOR XI | Authors: | Samuel, D, Cheng, H, Riley, P.W, Canutescu, A.A, Bu, Z, Walsh, P.N, Roder, H. | Deposit date: | 2006-10-25 | Release date: | 2007-10-02 | Last modified: | 2011-07-13 | Method: | SOLUTION NMR | Cite: | Solution Structure of the A4 Domain of Factor Xi Sheds Light on the Mechanism of Zymogen Activation. Proc.Natl.Acad.Sci.USA, 104, 2007
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2IO1
| Crystal structure of human Senp2 in complex with preSUMO-3 | Descriptor: | Sentrin-specific protease 2, Small ubiquitin-related modifier 3 precursor | Authors: | Reverter, D, Lima, C.D. | Deposit date: | 2006-10-09 | Release date: | 2006-11-14 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Nat.Struct.Mol.Biol., 13, 2006
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1K51
| A G55A Mutation Induces 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus | Descriptor: | Protein L, ZINC ION | Authors: | O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J. | Deposit date: | 2001-10-09 | Release date: | 2001-12-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus. Structure, 9, 2001
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8JSC
| Structure of the FSP1 protein from Human | Descriptor: | 6-HYDROXY-FLAVIN-ADENINE DINUCLEOTIDE, Ferroptosis suppressor protein 1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Zhang, S.T, Jia, D. | Deposit date: | 2023-06-19 | Release date: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | FSP1 oxidizes NADPH to suppress ferroptosis. Cell Res., 33, 2023
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2J1V
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1K52
| Monomeric Protein L B1 Domain with a K54G mutation | Descriptor: | Protein L, ZINC ION | Authors: | O'Neill, J.W, Kim, D.E, Johnsen, K, Baker, D, Zhang, K.Y.J. | Deposit date: | 2001-10-09 | Release date: | 2001-12-05 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Single-site mutations induce 3D domain swapping in the B1 domain of protein L from Peptostreptococcus magnus. Structure, 9, 2001
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1K6G
| Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing | Descriptor: | RNA (5'-R(P*GP*GP*CP*GP*UP*CP*AP*UP*GP*AP*GP*UP*CP*CP*AP*UP*GP*GP*CP*GP*CP*C)-3') | Authors: | Lebars, I, Lamontagne, B, Yoshizawa, S, Abou Elela, S, Fourmy, D. | Deposit date: | 2001-10-16 | Release date: | 2001-12-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing. EMBO J., 20, 2001
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1K9D
| The 1.7 A crystal structure of alpha-D-glucuronidase, a family-67 glycoside hydrolase from Bacillus stearothermophilus T-1 | Descriptor: | GLYCEROL, alpha-D-glucuronidase | Authors: | Golan, G, Shallom, D, Teplitsky, A, Zaide, G, Shulami, S, Baasov, T, Stojanoff, V, Thompson, A, Shoham, Y, Shoham, G. | Deposit date: | 2001-10-29 | Release date: | 2002-10-29 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Crystal Structures of Geobacillus stearothermophilus {alpha}-Glucuronidase Complexed with Its Substrate and Products: MECHANISTIC IMPLICATIONS. J.Biol.Chem., 279, 2004
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2IXN
| CRYSTAL STRUCTURE OF THE PP2A PHOSPHATASE ACTIVATOR Ypa2 PTPA2 | Descriptor: | SERINE/THREONINE-PROTEIN PHOSPHATASE 2A ACTIVATOR 2 | Authors: | Leulliot, N, Vicentini, G, Jordens, J, Quevillon-Cheruel, S, Schiltz, M, Barford, D, Van Tilbeurgh, H, Goris, J. | Deposit date: | 2006-07-09 | Release date: | 2006-07-31 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the Pp2A Phosphatase Activator: Implications for its Pp2A-Specific Ppiase Activity Mol.Cell, 23, 2006
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1K3R
| Crystal Structure of the Methyltransferase with a Knot from Methanobacterium thermoautotrophicum | Descriptor: | conserved protein MT0001 | Authors: | Zarembinski, T.I, Kim, Y, Peterson, K, Christendat, D, Dharamsi, A, Arrowsmith, C.H, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2001-10-03 | Release date: | 2002-05-15 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Deep trefoil knot implicated in RNA binding found in an archaebacterial protein. Proteins, 50, 2003
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2IW5
| Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase | Descriptor: | AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H. | Deposit date: | 2006-06-26 | Release date: | 2006-08-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.57 Å) | Cite: | Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase Mol.Cell, 23, 2006
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1K5O
| CPI-17(35-120) deletion mutant | Descriptor: | CPI-17 | Authors: | Ohki, S, Eto, M, Kariya, E, Hayano, T, Hayashi, Y, Yazawa, M, Brautigan, D, Kainosho, M. | Deposit date: | 2001-10-11 | Release date: | 2002-10-11 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of the Myosin Phosphatase Inhibitor Protein CPI-17 Shows Phosphorylation-induced Conformational Changes Responsible for Activation J.Mol.Biol., 314, 2001
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