4M1J
Crystal structure of Pseudomonas aeruginosa PvdQ in complex with a transition state analogue
Summary for 4M1J
Entry DOI | 10.2210/pdb4m1j/pdb |
Descriptor | Acyl-homoserine lactone acylase PvdQ subunit beta, Acyl-homoserine lactone acylase PvdQ subunit alpha, tridecylboronic acid, ... (5 entities in total) |
Functional Keywords | transition state analogue, heterodimer, acylase, boronic acid, secreted, hydrolase |
Biological source | Pseudomonas aeruginosa More |
Cellular location | Periplasm : Q9I194 Q9I194 |
Total number of polymer chains | 2 |
Total formula weight | 80695.33 |
Authors | Wu, R.,Clevenger, K.,Er, J.,Fast, W.L.,Liu, D. (deposition date: 2013-08-02, release date: 2013-08-28, Last modification date: 2017-11-15) |
Primary citation | Clevenger, K.D.,Wu, R.,Er, J.A.,Liu, D.,Fast, W. Rational Design of a Transition State Analogue with Picomolar Affinity for Pseudomonas aeruginosa PvdQ, a Siderophore Biosynthetic Enzyme. Acs Chem.Biol., 8:2192-2200, 2013 Cited by PubMed: 23883096DOI: 10.1021/cb400345h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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